Protein: MEPE
Matrix extracellular phosphoglycoprotein (Osteoblast/osteocyte factor 45) (OF45) (Osteoregulin)

Gene: MEPE
Organism: Homo sapiens
Interactions: 18
UniProt ID: Q9NQ76

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0005201 - extracellular matrix structural constituent
GO:0005576 - extracellular region
GO:0005788 - endoplasmic reticulum lumen
GO:0031012 - extracellular matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

389523

FINC
Fibronectin

2

0

High-throughput

0.602

High

1008676

PHEX
Phosphate-regulating neutral endopeptidase PHEX

1

0

Small-scale

0.505

High

362381

ABL1
Tyrosine-protein kinase ABL1

1

2

High-throughput

0.437

High

440743

FYN
Tyrosine-protein kinase Fyn

1

2

High-throughput

0.437

High

557483

SRC
Proto-oncogene tyrosine-protein kinase Src

1

2

High-throughput

0.437

High

594111

NCK1
SH2/SH3 adapter protein NCK1

1

4

High-throughput

0.437

High

855769

CRK
Adapter molecule crk

1

3

High-throughput

0.437

High

987964

GRB2
Growth factor receptor-bound protein 2

1

4

High-throughput

0.437

High

1312610

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

Small-scale

0.426

High

1022654

LRP2
Low-density lipoprotein receptor-related protein 2

2

0

High-throughput

0.328

High

1153742

TOM34
Mitochondrial import receptor subunit TOM34

2

0

High-throughput

0.328

High

1179741

ZXDC
Zinc finger protein ZXDC

2

0

High-throughput

0.316

High

163172

CHK1
Serine/threonine-protein kinase Chk1

1

0

Small-scale

0.288

High

595606

H15
Histone H1.5

1

0

High-throughput

0.269

Low

404449

GCR
Glucocorticoid receptor

1

0

High-throughput

0.249

Low

619113

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.249

Low

623557

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

High-throughput

0.249

Low

699866

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025