Protein: PALB2
Partner and localizer of BRCA2

Gene: PALB2
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q86YC2

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0001756 - somitogenesis
GO:0001833 - inner cell mass cell proliferation
GO:0003677 - DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

847841

BRCA2
Breast cancer type 2 susceptibility protein

29

1

Small-scale

0.770

High

749651

BRCA1
Breast cancer type 1 susceptibility protein

19

1

Small-scale

0.766

High

1205493

MO4L1
Mortality factor 4-like protein 1

15

1

Small-scale

0.764

High

988100

RAD51
DNA repair protein RAD51 homolog 1

15

3

Small-scale

0.763

High

1063010

MO4L2
Mortality factor 4-like protein 2

6

1

Small-scale

0.736

High

1049255

KEAP1
Kelch-like ECH-associated protein 1

11

0

Small-scale

0.727

High

1205472

PALB2
Partner and localizer of BRCA2

4

1

Small-scale

0.683

High

206283

RA51C
DNA repair protein RAD51 homolog 3

1

3

Small-scale

0.597

High

1205490

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

2

0

Small-scale

0.592

High

850107

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

2

Small-scale

0.586

High

917542

H4
Histone H4

2

0

Small-scale

0.569

High

934943

H31
Histone H3.1

2

0

Small-scale

0.569

High

207068

XRCC3
DNA repair protein XRCC3

1

3

Small-scale

0.568

High

1205497

POLH
DNA polymerase eta

1

0

Small-scale

0.561

High

1205496

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

1

Small-scale

0.561

High

1205473

RN168
E3 ubiquitin-protein ligase RNF168

1

0

Small-scale

0.537

High

782357

KDM5C
Lysine-specific demethylase 5C

1

1

High-throughput

0.536

High

1205474

NEK7
Serine/threonine-protein kinase Nek7

1

1

High-throughput

0.536

High

326704

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.518

High

1022379

IL24
Interleukin-24

1

0

High-throughput

0.518

High

1119178

GREB1
Protein GREB1

1

0

High-throughput

0.518

High

1200820

CASZ1
Zinc finger protein castor homolog 1

1

0

High-throughput

0.518

High

1205476

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.518

High

1205477

KLK6
Kallikrein-6

1

0

High-throughput

0.518

High

1205485

PRD14
PR domain zinc finger protein 14

1

0

High-throughput

0.518

High

1205488

BCAS3
BCAS3 microtubule associated cell migration factor

1

0

High-throughput

0.518

High

1205494

ERRFI
ERBB receptor feedback inhibitor 1

1

0

High-throughput

0.518

High

363837

ALBU
Albumin

1

0

High-throughput

0.513

High

1041965

CUL3
Cullin-3

1

0

Small-scale

0.513

High

1205482

CTIP
DNA endonuclease RBBP8

1

0

Small-scale

0.513

High

1205483

FANCJ
Fanconi anemia group J protein

1

0

Small-scale

0.513

High

271137

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

2

Small-scale

0.501

High

707679

H2B1B
Histone H2B type 1-B

1

2

Small-scale

0.501

High

851573

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.489

High

1205478

R51A1
RAD51-associated protein 1

1

0

Small-scale

0.480

High

666541

KDM5A
Lysine-specific demethylase 5A

1

1

High-throughput

0.479

High

918495

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

1087237

H2B2E
Histone H2B type 2-E

1

2

Small-scale

0.479

High

1205498

MOFA1
MORF4 family-associated protein 1

1

1

High-throughput

0.479

High

173973

ATX7
Ataxin-7

1

0

Small-scale

0.458

High

232294

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

257803

SIN3B
Paired amphipathic helix protein Sin3b

1

0

High-throughput

0.458

High

275273

RNH2A
Ribonuclease H2 subunit A

1

0

Small-scale

0.458

High

432795

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

Small-scale

0.458

High

553110

RFA2
Replication protein A 32 kDa subunit

1

0

Small-scale

0.458

High

659932

ERCC5
DNA excision repair protein ERCC-5

1

0

Small-scale

0.458

High

831471

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

1038504

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

1062104

AT7L3
Ataxin-7-like protein 3

1

0

Small-scale

0.458

High

1190847

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

0

High-throughput

0.458

High

1191249

DPOLN
DNA polymerase nu

1

0

Small-scale

0.458

High

1193116

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1205475

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1205481

PHF12
PHD finger protein 12

1

0

High-throughput

0.458

High

1205486

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

1205487

BRD8
Bromodomain-containing protein 8

1

0

High-throughput

0.458

High

1205489

ENY2
Transcription and mRNA export factor ENY2

1

0

Small-scale

0.458

High

1205491

MRGBP
MRG/MORF4L-binding protein

1

0

High-throughput

0.458

High

1205495

RCOR1
REST corepressor 1

1

0

High-throughput

0.458

High

1205479

MR1L1
MORF4 family-associated protein 1-like 1

1

1

High-throughput

0.437

High

310313

LYPD3
Ly6/PLAUR domain-containing protein 3

1

0

High-throughput

0.282

High

318177

DIRA3
GTP-binding protein Di-Ras3

1

0

High-throughput

0.282

High

506499

ARY2
Arylamine N-acetyltransferase 2

1

0

High-throughput

0.282

High

528268

CCL5
C-C motif chemokine 5

1

0

High-throughput

0.282

High

738778

SPB5
Serpin B5

1

0

High-throughput

0.282

High

1056211

I13R2
Interleukin-13 receptor subunit alpha-2

1

0

High-throughput

0.282

High

1079035

CYTM
Cystatin-M

1

0

High-throughput

0.282

High

1205480

LRAT2
Protein LRATD2

1

0

High-throughput

0.282

High

1205484

RHBT2
Rho-related BTB domain-containing protein 2

1

0

High-throughput

0.282

High

1205492

MRC2
C-type mannose receptor 2

1

0

High-throughput

0.282

High

270069

RF1M
Peptide chain release factor 1, mitochondrial

1

0

High-throughput

0.279

Low

661336

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

975690

LMNB2
Lamin-B2

1

0

High-throughput

0.279

Low

427905

CAN1
Calpain-1 catalytic subunit

1

0

Small-scale

0.249

Low

1168564

SYNE3
Nesprin-3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024