Protein: TPP2
Tripeptidyl-peptidase 2 (TPP-2) (EC 3.4.14.10) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase II) (TPP-II)

Gene: TPP2
Organism: Homo sapiens
Interactions: 110
UniProt ID: P29144

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004175 - endopeptidase activity
GO:0004177 - aminopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

664243

DOK3
Docking protein 3

3

1

High-throughput

0.667

High

417807

DPOLB
DNA polymerase beta

3

0

High-throughput

0.654

High

664246

CARME
Carnosine N-methyltransferase

3

0

High-throughput

0.638

High

664264

CHIA
Acidic mammalian chitinase

3

0

High-throughput

0.638

High

664270

DEN2D
DENN domain-containing protein 2D

3

0

High-throughput

0.638

High

664252

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

1

High-throughput

0.628

High

664256

PP16A
Protein phosphatase 1 regulatory subunit 16A

2

2

High-throughput

0.628

High

664210

TPP2
Tripeptidyl-peptidase 2

1

13

Small-scale

0.621

High

616943

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

2

High-throughput

0.618

High

664242

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.618

High

456306

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

2

0

High-throughput

0.602

High

664042

T2EB
Transcription initiation factor IIE subunit beta

2

0

High-throughput

0.602

High

664244

NAA40
N-alpha-acetyltransferase 40

2

0

High-throughput

0.602

High

664251

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

0

High-throughput

0.602

High

664227

ECHP
Peroxisomal bifunctional enzyme

2

2

High-throughput

0.596

High

226602

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

664282

ZRAN1
Ubiquitin thioesterase ZRANB1

2

1

High-throughput

0.584

High

506437

RALB
Ras-related protein Ral-B

2

3

High-throughput

0.574

High

664230

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

2

1

High-throughput

0.571

High

664268

CAD19
Cadherin-19

2

2

High-throughput

0.558

High

433600

LYN
Tyrosine-protein kinase Lyn

2

0

High-throughput

0.547

High

664260

SCLT1
Sodium channel and clathrin linker 1

2

0

High-throughput

0.547

High

182091

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

2

High-throughput

0.536

High

225125

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

2

High-throughput

0.536

High

240354

SNX2
Sorting nexin-2

1

1

High-throughput

0.536

High

337984

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.536

High

509910

VDR
Vitamin D3 receptor

1

1

High-throughput

0.536

High

664221

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.536

High

664223

NCALD
Neurocalcin-delta

1

2

High-throughput

0.536

High

664225

HPCA
Neuron-specific calcium-binding protein hippocalcin

1

2

High-throughput

0.536

High

664236

AAK1
AP2-associated protein kinase 1

1

3

High-throughput

0.536

High

664253

PSPC1
Paraspeckle component 1

1

1

High-throughput

0.536

High

664254

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.536

High

664284

CILK1
Serine/threonine-protein kinase ICK

1

1

High-throughput

0.536

High

196032

RRP8
Ribosomal RNA-processing protein 8

1

0

High-throughput

0.513

High

273010

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.513

High

380244

HG2A
HLA class II histocompatibility antigen gamma chain

1

0

High-throughput

0.513

High

574249

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

664211

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

664217

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

664228

SBP1
Methanethiol oxidase

1

0

High-throughput

0.513

High

664231

ARHG7
Rho guanine nucleotide exchange factor 7

1

0

High-throughput

0.513

High

664245

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

0

High-throughput

0.513

High

664257

Z512B
Zinc finger protein 512B

1

0

High-throughput

0.513

High

664262

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

664271

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

664275

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.513

High

664233

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.489

High

664235

NTRK3
NT-3 growth factor receptor

1

1

High-throughput

0.489

High

664238

ANR39
Ankyrin repeat domain-containing protein 39

1

2

High-throughput

0.489

High

664277

ABCF3
ATP-binding cassette sub-family F member 3

1

1

High-throughput

0.489

High

664285

NTNG1
Netrin-G1

1

2

High-throughput

0.489

High

664279

TBA8
Tubulin alpha-8 chain

1

1

High-throughput

0.481

High

386156

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

428035

TBB5
Tubulin beta chain

1

2

High-throughput

0.479

High

437917

HS90B
Heat shock protein HSP 90-beta

1

5

High-throughput

0.479

High

650438

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

664220

ATX1
Ataxin-1

1

1

High-throughput

0.479

High

664226

PO5F1
POU domain, class 5, transcription factor 1

1

2

High-throughput

0.479

High

664229

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

664234

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.479

High

664249

RIN3
Ras and Rab interactor 3

1

1

High-throughput

0.479

High

664269

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

664287

3BP1
SH3 domain-binding protein 1

1

1

High-throughput

0.479

High

664218

MTR1A
Melatonin receptor type 1A

1

1

High-throughput

0.464

High

664281

FXL17
F-box/LRR-repeat protein 17

1

0

Small-scale

0.460

High

311482

SMC2
Structural maintenance of chromosomes protein 2

1

0

High-throughput

0.458

High

552012

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

617438

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

625140

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

664212

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

664213

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

664214

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

664215

LICH
Lysosomal acid lipase/cholesteryl ester hydrolase

1

0

High-throughput

0.458

High

664216

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

664224

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

664232

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

664237

MIDN
Midnolin

1

0

High-throughput

0.458

High

664250

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.458

High

664255

SPDLY
Protein Spindly

1

0

High-throughput

0.458

High

664266

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.458

High

664272

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

664273

RC3H2
Roquin-2

1

0

High-throughput

0.458

High

664276

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

664265

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

354310

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

3

High-throughput

0.437

High

384327

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

664278

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

330868

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.426

High

496374

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

664219

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

664258

Q96KY9
CDH19 protein

1

1

High-throughput

0.407

High

388857

CP1A1
Cytochrome P450 1A1

3

0

High-throughput

0.347

High

664247

KLH36
Kelch-like protein 36

2

0

High-throughput

0.328

High

664283

PCDGG
Protocadherin gamma-B4

2

0

High-throughput

0.328

High

648462

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

664222

T2R31
Taste receptor type 2 member 31

1

0

High-throughput

0.279

Low

664239

TMM69
Transmembrane protein 69

1

0

High-throughput

0.279

Low

664240

SCYL2
SCY1-like protein 2

1

0

High-throughput

0.279

Low

664241

PPR21
Protein phosphatase 1 regulatory subunit 21

1

0

High-throughput

0.279

Low

664248

F133A
Protein FAM133A

1

0

High-throughput

0.279

Low

664259

ZN75A
Zinc finger protein 75A

1

0

High-throughput

0.279

Low

664261

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

664263

TSSK1
Testis-specific serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

664267

CF062
Uncharacterized protein C6orf62

1

0

High-throughput

0.279

Low

664274

WFDC1
WAP four-disulfide core domain protein 1

1

0

High-throughput

0.279

Low

664288

O10H1
Olfactory receptor 10H1

1

0

High-throughput

0.279

Low

664280

TOM7
Mitochondrial import receptor subunit TOM7 homolog

1

0

High-throughput

0.249

Low

664286

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024