Protein: AT7L3
Ataxin-7-like protein 3 (SAGA-associated factor 11 homolog)

Gene: AT7L3, ATXN7L3
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q14CW9

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0006282 - regulation of DNA repair
GO:0006325 - chromatin organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1135648

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

14

4

Small-scale

0.982

High

67130

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

5

4

High-throughput

0.925

High

1135624

UBP51
Ubiquitin carboxyl-terminal hydrolase 51

3

4

High-throughput

0.855

High

1135643

ENY2
Transcription and mRNA export factor ENY2

11

4

Small-scale

0.759

High

1135650

TRRAP
Transformation/transcription domain-associated protein

10

1

Small-scale

0.754

High

1135630

KAT2A
Histone acetyltransferase KAT2A

11

4

Small-scale

0.754

High

184712

ATX7
Ataxin-7

10

2

Small-scale

0.753

High

1135636

SGF29
SAGA-associated factor 29

9

1

Small-scale

0.751

High

284948

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

8

1

Small-scale

0.748

High

283600

SUPT3
Transcription initiation protein SPT3 homolog

7

1

Small-scale

0.746

High

284829

TADA3
Transcriptional adapter 3

7

1

Small-scale

0.745

High

1135626

TAD2B
Transcriptional adapter 2-beta

7

1

Small-scale

0.745

High

1135633

TADA1
Transcriptional adapter 1

7

1

Small-scale

0.745

High

1135619

TAF9
Transcription initiation factor TFIID subunit 9

7

1

Small-scale

0.742

High

1135631

KAT2B
Histone acetyltransferase KAT2B

6

4

High-throughput

0.733

High

1135642

TAF9B
Transcription initiation factor TFIID subunit 9B

6

1

Small-scale

0.733

High

1091611

TAF10
Transcription initiation factor TFIID subunit 10

6

1

Small-scale

0.726

High

1135628

SP20H
Transcription factor SPT20 homolog

8

0

Small-scale

0.716

High

319147

ST65G
STAGA complex 65 subunit gamma

7

0

Small-scale

0.713

High

1135651

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

5

1

Small-scale

0.712

High

1135618

TAF12
Transcription initiation factor TFIID subunit 12

6

0

Small-scale

0.699

High

907434

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

4

High-throughput

0.691

High

1135622

AT7L2
Ataxin-7-like protein 2

6

2

High-throughput

0.668

High

1135647

AT7L1
Ataxin-7-like protein 1

6

2

High-throughput

0.668

High

1135625

H32
Histone H3.2

1

0

High-throughput

0.656

High

762698

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

1

High-throughput

0.625

High

1135620

H2A2C
Histone H2A type 2-C

1

0

Small-scale

0.614

High

1135621

H2B2E
Histone H2B type 2-E

1

0

Small-scale

0.614

High

1135632

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

4

High-throughput

0.575

High

396131

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

507992

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

1135645

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.486

High

143001

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

473995

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.479

High

1087746

NFIA
Nuclear factor 1 A-type

1

3

High-throughput

0.479

High

1133417

NFIX
Nuclear factor 1 X-type

1

3

High-throughput

0.479

High

1135639

SF3B5
Splicing factor 3B subunit 5

1

1

High-throughput

0.479

High

372058

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

979676

H4
Histone H4

1

0

High-throughput

0.458

High

1045302

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1135615

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

1135616

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.458

High

1135627

PALB2
Partner and localizer of BRCA2

1

0

Small-scale

0.458

High

1135635

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

0

Small-scale

0.458

High

1135638

KLF6
Krueppel-like factor 6

1

0

High-throughput

0.458

High

1135623

FBX38
F-box only protein 38

1

0

High-throughput

0.426

High

1135629

ARB2A
Cotranscriptional regulator ARB2A

1

0

High-throughput

0.426

High

1135634

CENPT
Centromere protein T

1

0

High-throughput

0.426

High

1135649

KAD6
Adenylate kinase isoenzyme 6

1

0

High-throughput

0.426

High

583865

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

0

High-throughput

0.282

High

1135637

SEBP2
Selenocysteine insertion sequence-binding protein 2

1

0

High-throughput

0.282

High

996699

TBA1B
Tubulin alpha-1B chain

1

0

High-throughput

0.279

Low

1123289

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.279

Low

1135617

TBCC
Tubulin-specific chaperone C

1

0

High-throughput

0.279

Low

1135640

NADAP
Kanadaptin

1

0

High-throughput

0.279

Low

1135646

TSKS
Testis-specific serine kinase substrate

1

0

High-throughput

0.279

Low

1135644

PICK1
PRKCA-binding protein

1

0

High-throughput

0.265

Low

422117

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

289083

DEDD
Death effector domain-containing protein

1

0

High-throughput

0.232

Low

1135641

GL8D2
Glycosyltransferase 8 domain-containing protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025