Protein: CLD3
Claudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-R 2) (CPE-receptor 2) (Rat ventral prostate.1 protein homolog) (hRVP1)

Gene: CLD3, CLDN3
Organism: Homo sapiens
Interactions: 22
UniProt ID: O15551

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0003382 - epithelial cell morphogenesis
GO:0003406 - retinal pigment epithelium development
GO:0004888 - transmembrane signaling receptor activity
GO:0005198 - structural molecule activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

138544

CLD5
Claudin-5

1

6

Small-scale

0.618

High

194636

CLD1
Claudin-1

1

6

Small-scale

0.618

High

194639

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

194650

AN13D
Ankyrin repeat domain-containing protein 13D

1

1

High-throughput

0.536

High

194654

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

10

High-throughput

0.536

High

193073

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

0

High-throughput

0.513

High

194635

CHM2A
Charged multivesicular body protein 2a

1

0

High-throughput

0.513

High

194640

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

194648

ZO1
Tight junction protein 1

1

20

Small-scale

0.501

High

194637

RASH
GTPase HRas

1

3

High-throughput

0.479

High

194638

RASK
GTPase KRas

1

4

High-throughput

0.479

High

194641

RAC2
Ras-related C3 botulinum toxin substrate 2

1

3

High-throughput

0.479

High

194642

EGR1
Early growth response protein 1

1

1

High-throughput

0.479

High

194644

RAC3
Ras-related C3 botulinum toxin substrate 3

1

3

High-throughput

0.479

High

194645

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.479

High

194646

RHOB
Rho-related GTP-binding protein RhoB

1

5

High-throughput

0.479

High

194647

RAC1
Ras-related C3 botulinum toxin substrate 1

1

3

High-throughput

0.479

High

194649

RHOH
Rho-related GTP-binding protein RhoH

1

6

High-throughput

0.479

High

194651

GOLM1
Golgi membrane protein 1

1

1

Small-scale

0.445

High

194652

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

194653

ISOC2
Isochorismatase domain-containing protein 2

1

0

High-throughput

0.279

Low

194643

CATS
Cathepsin S

1

0

Small-scale

0.269

Low


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Last updated: 11Aug2025