Protein: UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)

Gene: UCHL1
Organism: Mus musculus
Interactions: 24
UniProt ID: Q9R0P9

Gene Ontology (top 5):
GO:0002176 - male germ cell proliferation
GO:0002931 - response to ischemia
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509316

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

2

14

Small-scale

0.806

High

1455950

PRKN
E3 ubiquitin-protein ligase parkin

1

18

Small-scale

0.647

High

543038

CDK1
Cyclin-dependent kinase 1

2

4

Small-scale

0.571

High

1064178

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

2

High-throughput

0.536

High

928109

ATX1
Ataxin-1

1

0

High-throughput

0.493

High

205620

CSN5
COP9 signalosome complex subunit 5

1

13

Small-scale

0.479

High

530938

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.479

High

582016

NTRK2
BDNF/NT-3 growth factors receptor

1

5

Small-scale

0.479

High

600596

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

Small-scale

0.479

High

997273

TBA1A
Tubulin alpha-1A chain

1

10

Small-scale

0.479

High

1191263

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

6

High-throughput

0.479

High

1247236

NEB2
Neurabin-2

1

3

High-throughput

0.479

High

1253548

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.479

High

1362265

SHRPN
Sharpin

1

1

Small-scale

0.479

High

1362896

RHEB
GTP-binding protein Rheb

1

7

High-throughput

0.479

High

1424314

WWTR1
WW domain-containing transcription regulator protein 1

1

2

Small-scale

0.479

High

534036

OSTP
Osteopontin

1

0

Small-scale

0.458

High

1065061

CD36
Platelet glycoprotein 4

1

0

Small-scale

0.458

High

1362243

PTOV1
Prostate tumor-overexpressed gene 1 protein homolog

1

0

Small-scale

0.458

High

718982

CDK4
Cyclin-dependent kinase 4

1

7

Small-scale

0.445

High

1296762

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

9

High-throughput

0.445

High

1298539

FTM
Protein fantom

1

13

High-throughput

0.445

High

1296434

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

1

High-throughput

0.437

High

1424090

ATAD1
Outer mitochondrial transmembrane helix translocase

1

10

Small-scale

0.437

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025