Protein: SGSM2
Small G protein signaling modulator 2 (RUN and TBC1 domain-containing protein 1)

Gene: SGSM2
Organism: Homo sapiens
Interactions: 26
UniProt ID: O43147

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0031267 - small GTPase binding
GO:0034499 - late endosome to Golgi transport
GO:0042470 - melanosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

207699

RAB9A
Ras-related protein Rab-9A

1

20

Small-scale

0.740

High

207697

RAB3B
Ras-related protein Rab-3B

1

15

Small-scale

0.621

High

207702

RAB2A
Ras-related protein Rab-2A

1

20

Small-scale

0.621

High

207705

CETN1
Centrin-1

2

10

High-throughput

0.574

High

207708

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

2

5

High-throughput

0.574

High

207696

RAB3A
Ras-related protein Rab-3A

1

16

Small-scale

0.555

High

207710

RAB2B
Ras-related protein Rab-2B

1

20

Small-scale

0.555

High

207714

RAB9B
Ras-related protein Rab-9B

1

20

Small-scale

0.555

High

207694

EGFR
Epidermal growth factor receptor

1

5

High-throughput

0.541

High

207706

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.541

High

207709

FBP1L
Formin-binding protein 1-like

1

1

High-throughput

0.541

High

207713

GDPD2
Glycerophosphoinositol inositolphosphodiesterase GDPD2

1

1

High-throughput

0.541

High

207695

FETA
Alpha-fetoprotein

1

0

High-throughput

0.518

High

207703

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.518

High

207704

EM55
55 kDa erythrocyte membrane protein

1

4

High-throughput

0.494

High

207711

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

4

High-throughput

0.489

High

207716

DCA13
DDB1- and CUL4-associated factor 13

1

1

Small-scale

0.437

High

207700

GPC3
Glypican-3

1

1

High-throughput

0.407

High

207692

CAH12
Carbonic anhydrase 12

1

0

High-throughput

0.282

High

207693

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

0

High-throughput

0.282

High

207698

PTN
Pleiotrophin

1

0

High-throughput

0.282

High

207712

RGMA
Repulsive guidance molecule A

1

0

High-throughput

0.282

High

207715

PNO1
RNA-binding protein PNO1

1

0

High-throughput

0.282

High

207717

CELR3
Cadherin EGF LAG seven-pass G-type receptor 3

1

0

High-throughput

0.282

High

207701

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low

207707

ILF2
Interleukin enhancer-binding factor 2

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025