Protein: CARL2
Capping protein, Arp2/3 and myosin-I linker protein 2 (Capping protein regulator and myosin 1 linker 2) (F-actin-uncapping protein RLTPR) (Leucine-rich repeat-containing protein 16C) (RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein)

Gene: CARL2, CARMIL2
Organism: Homo sapiens
Interactions: 26
UniProt ID: Q6F5E8

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0005543 - phospholipid binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007163 - establishment or maintenance of cell polarity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

866721

CAZA2
F-actin-capping protein subunit alpha-2

4

8

High-throughput

0.892

High

867208

CAPZB
F-actin-capping protein subunit beta

3

4

High-throughput

0.839

High

915112

CAZA1
F-actin-capping protein subunit alpha-1

1

8

High-throughput

0.665

High

373994

RASN
GTPase NRas

1

11

High-throughput

0.618

High

375616

RASK
GTPase KRas

1

11

High-throughput

0.618

High

988446

RAC1
Ras-related C3 botulinum toxin substrate 1

1

13

High-throughput

0.618

High

1015523

RHOG
Rho-related GTP-binding protein RhoG

1

12

High-throughput

0.618

High

966466

1433G
14-3-3 protein gamma

1

15

High-throughput

0.554

High

1049419

1433F
14-3-3 protein eta

1

15

High-throughput

0.554

High

857477

NOTC1
Neurogenic locus notch homolog protein 1

1

3

High-throughput

0.536

High

1232324

FOXD3
Forkhead box protein D3

1

9

High-throughput

0.489

High

680396

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

2

High-throughput

0.479

High

691124

1433T
14-3-3 protein theta

1

15

High-throughput

0.479

High

729942

1433B
14-3-3 protein beta/alpha

1

15

High-throughput

0.479

High

971643

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.479

High

990352

1433Z
14-3-3 protein zeta/delta

1

15

High-throughput

0.479

High

1232320

NIN
Ninein

1

11

High-throughput

0.479

High

1232323

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1232319

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

6

High-throughput

0.470

High

1232321

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

4

High-throughput

0.445

High

1232318

PAXI1
PAX-interacting protein 1

1

4

High-throughput

0.437

High

635886

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.426

High

1232325

S45A1
Proton-associated sugar transporter A

1

0

High-throughput

0.426

High

219492

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.279

Low

282389

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.249

Low

1232322

MBD5
Methyl-CpG-binding domain protein 5

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025