Protein: FGD4
FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6)

Gene: FGD4
Organism: Homo sapiens
Interactions: 20
UniProt ID: Q96M96

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0003779 - actin binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

603335

KPCA
Protein kinase C alpha type

2

13

High-throughput

0.811

High

1206382

FGD3
FYVE, RhoGEF and PH domain-containing protein 3

2

14

High-throughput

0.789

High

955483

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.647

High

1140704

KIF14
Kinesin-like protein KIF14

1

13

High-throughput

0.618

High

396736

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1361212

DNJC9
DnaJ homolog subfamily C member 9

2

4

High-throughput

0.571

High

228505

LANC1
Glutathione S-transferase LANCL1

2

0

High-throughput

0.547

High

1397898

BBLN
Bublin coiled-coil protein

1

1

High-throughput

0.481

High

242620

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

442448

GELS
Gelsolin

1

10

High-throughput

0.479

High

451243

NFL
Neurofilament light polypeptide

1

20

High-throughput

0.479

High

866788

CAZA2
F-actin-capping protein subunit alpha-2

1

5

High-throughput

0.479

High

953045

ACTB
Actin, cytoplasmic 1

1

16

High-throughput

0.479

High

1114033

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1143235

PLEC
Plectin

1

20

High-throughput

0.479

High

1247508

POTEE
POTE ankyrin domain family member E

1

16

High-throughput

0.479

High

717577

PDIA3
Protein disulfide-isomerase A3

1

7

High-throughput

0.437

High

1053380

CTSL2
CTD small phosphatase-like protein 2

1

3

High-throughput

0.437

High

1397899

CCD86
Coiled-coil domain-containing protein 86

1

2

High-throughput

0.437

High

1333478

GOLM1
Golgi membrane protein 1

1

0

Small-scale

0.426

High


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Last updated: 11Aug2025