Protein: SGO1
Shugoshin 1 (Serologically defined breast cancer antigen NY-BR-85) (Shugoshin-like 1)

Gene: SGO1
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q5FBB7

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0000779 - condensed chromosome, centromeric region
GO:0000922 - spindle pole
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

930874

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

8

1

Small-scale

0.753

High

915211

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

4

1

High-throughput

0.699

High

800408

CBX5
Chromobox protein homolog 5

4

2

Small-scale

0.698

High

672153

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

3

1

High-throughput

0.678

High

949803

CBX1
Chromobox protein homolog 1

3

2

Small-scale

0.661

High

1069249

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

3

4

Small-scale

0.660

High

1058674

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

3

4

Small-scale

0.650

High

224450

RAD21
Double-strand-break repair protein rad21 homolog

3

0

Small-scale

0.638

High

1125667

STAG2
Cohesin subunit SA-2

3

0

Small-scale

0.638

High

1032370

2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

2

4

Small-scale

0.611

High

1027030

CBX3
Chromobox protein homolog 3

2

2

Small-scale

0.606

High

1057279

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

Small-scale

0.571

High

1100504

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

1

Small-scale

0.554

High

1069888

PTPA
Serine/threonine-protein phosphatase 2A activator

1

0

Small-scale

0.537

High

259288

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

1

High-throughput

0.536

High

296311

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

2

High-throughput

0.536

High

672432

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

1

High-throughput

0.536

High

905384

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

1

High-throughput

0.536

High

1069284

2A5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

1

4

High-throughput

0.536

High

1082508

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

1

4

High-throughput

0.536

High

1125675

CDCA5
Sororin

1

0

Small-scale

0.530

High

1121600

BOREA
Borealin

1

0

Small-scale

0.518

High

261528

NCOR1
Nuclear receptor corepressor 1

1

0

High-throughput

0.513

High

319868

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.513

High

676680

AL1B1
Aldehyde dehydrogenase X, mitochondrial

1

0

High-throughput

0.513

High

816251

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

1

0

High-throughput

0.513

High

863739

CATC
Dipeptidyl peptidase 1

1

0

High-throughput

0.513

High

884315

PCBP3
Poly(rC)-binding protein 3

1

0

High-throughput

0.513

High

963833

SET
Protein SET

1

0

High-throughput

0.513

High

988083

RAD51
DNA repair protein RAD51 homolog 1

1

0

High-throughput

0.513

High

1022510

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.513

High

1125659

CTR9
RNA polymerase-associated protein CTR9 homolog

1

0

High-throughput

0.513

High

1125661

SPT6H
Transcription elongation factor SPT6

1

0

High-throughput

0.513

High

1125664

WAPL
Wings apart-like protein homolog

1

0

Small-scale

0.513

High

1125665

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

0

High-throughput

0.513

High

1125666

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.513

High

1125669

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

High-throughput

0.513

High

1125670

WDR48
WD repeat-containing protein 48

1

0

High-throughput

0.513

High

1125671

WDR20
WD repeat-containing protein 20

1

0

High-throughput

0.513

High

1125673

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.513

High

1125674

KAT6B
Histone acetyltransferase KAT6B

1

0

High-throughput

0.513

High

1125681

KIF2C
Kinesin-like protein KIF2C

1

0

High-throughput

0.513

High

1125682

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

0

High-throughput

0.513

High

1125687

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.513

High

1125690

RNC
Ribonuclease 3

1

0

High-throughput

0.513

High

1125693

DNM3B
DNA

1

0

High-throughput

0.513

High

1125694

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.513

High

1125695

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

High-throughput

0.513

High

1125696

HPS5
BLOC-2 complex member HPS5

1

0

High-throughput

0.513

High

1125697

CHM2B
Charged multivesicular body protein 2b

1

0

High-throughput

0.513

High

1125691

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

2

Small-scale

0.500

High

919996

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.493

High

934845

H31
Histone H3.1

1

1

High-throughput

0.479

High

952381

H33
Histone H3.3

1

1

High-throughput

0.479

High

1072231

ELOC
Elongin-C

1

1

High-throughput

0.479

High

1125680

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

1

High-throughput

0.479

High

1125688

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

1

High-throughput

0.479

High

236941

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

0

Small-scale

0.458

High

386866

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

728617

PPM1A
Protein phosphatase 1A

1

0

Small-scale

0.458

High

861782

PLK1
Serine/threonine-protein kinase PLK1

1

0

Small-scale

0.458

High

918415

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

1024554

CAF1B
Chromatin assembly factor 1 subunit B

1

0

High-throughput

0.458

High

1125658

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.458

High

1125663

POGZ
Pogo transposable element with ZNF domain

1

0

High-throughput

0.458

High

1125672

CIP2A
Protein CIP2A

1

0

Small-scale

0.458

High

1125676

AURKB
Aurora kinase B

1

0

Small-scale

0.458

High

1125677

NSL1
Kinetochore-associated protein NSL1 homolog

1

0

High-throughput

0.458

High

1125678

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

0

High-throughput

0.458

High

1125683

MIS12
Protein MIS12 homolog

1

0

High-throughput

0.458

High

1125684

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.458

High

1125689

INCE
Inner centromere protein

1

0

Small-scale

0.458

High

1125686

ZN768
Zinc finger protein 768

1

1

High-throughput

0.437

High

91332

E5RHG8
Elongin-C

1

1

High-throughput

0.407

High

110667

H3BS42
Zinc finger protein 768

1

1

High-throughput

0.407

High

876605

AF17
Protein AF-17

2

0

High-throughput

0.328

High

277841

DYSF
Dysferlin

1

0

High-throughput

0.279

Low

661282

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

1125657

MTCL3
Microtubule cross-linking factor 3

1

0

High-throughput

0.279

Low

1125660

F10C1
Protein FRA10AC1

1

0

High-throughput

0.279

Low

1125668

KLH36
Kelch-like protein 36

1

0

High-throughput

0.279

Low

1125679

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.279

Low

1125692

IMPCT
Protein IMPACT

1

0

High-throughput

0.279

Low

100831

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

887244

ZN445
Zinc finger protein 445

1

0

High-throughput

0.249

Low

1024474

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.249

Low

1125662

LRC8D
Volume-regulated anion channel subunit LRRC8D

1

0

Small-scale

0.249

Low

1125685

ZN644
Zinc finger protein 644

1

0

High-throughput

0.249

Low

47421

RPSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024