Protein: AK1D1
Aldo-keto reductase family 1 member D1 (EC 1.3.1.3) (3-oxo-5-beta-steroid 4-dehydrogenase) (Delta(4)-3-ketosteroid 5-beta-reductase) (Delta(4)-3-oxosteroid 5-beta-reductase)

Gene: AK1D1, AKR1D1
Organism: Homo sapiens
Interactions: 9
UniProt ID: P51857

Gene Ontology (top 5):
GO:0004032 - aldose reductase (NADPH) activity
GO:0005496 - steroid binding
GO:0005829 - cytosol
GO:0006699 - bile acid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

238661

AK1BA
Aldo-keto reductase family 1 member B10

3

12

High-throughput

0.861

High

838903

AK1C3
Aldo-keto reductase family 1 member C3

3

11

High-throughput

0.861

High

908340

AK1C1
Aldo-keto reductase family 1 member C1

3

11

High-throughput

0.848

High

908342

GEMI5
Gem-associated protein 5

3

0

High-throughput

0.638

High

908343

SIR1
NAD-dependent protein deacetylase sirtuin-1

3

0

High-throughput

0.638

High

771104

APJ
Apelin receptor

2

3

High-throughput

0.574

High

908341

PXDC2
Plexin domain-containing protein 2

2

1

High-throughput

0.558

High

605130

KCRS
Creatine kinase S-type, mitochondrial

1

1

High-throughput

0.489

High

325392

DIRA1
GTP-binding protein Di-Ras1

3

0

High-throughput

0.347

High


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Last updated: 11Aug2025