Protein: K2C78
Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40)

Gene: K2C78, KRT78
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q8N1N4

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0030280 - structural constituent of skin epidermis
GO:0031424 - keratinization
GO:0045095 - keratin filament

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1055065

KT33B
Keratin, type I cuticular Ha3-II

2

20

High-throughput

0.794

High

1231025

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.794

High

280646

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.783

High

280814

KRT36
Keratin, type I cuticular Ha6

2

20

High-throughput

0.783

High

359381

K1C14
Keratin, type I cytoskeletal 14

2

20

High-throughput

0.783

High

444424

K1C19
Keratin, type I cytoskeletal 19

2

20

High-throughput

0.783

High

445086

K1C16
Keratin, type I cytoskeletal 16

2

20

High-throughput

0.783

High

580064

K1C15
Keratin, type I cytoskeletal 15

2

20

High-throughput

0.783

High

1071270

K1H1
Keratin, type I cuticular Ha1

2

20

High-throughput

0.783

High

1149419

K1C39
Keratin, type I cytoskeletal 39

2

20

High-throughput

0.783

High

1189597

K1C27
Keratin, type I cytoskeletal 27

2

20

High-throughput

0.783

High

1189697

K1C25
Keratin, type I cytoskeletal 25

2

20

High-throughput

0.783

High

1081732

AINX
Alpha-internexin

1

20

High-throughput

0.691

High

280895

KRT37
Keratin, type I cuticular Ha7

1

20

High-throughput

0.621

High

281018

KRT38
Keratin, type I cuticular Ha8

1

20

High-throughput

0.621

High

531496

K1C13
Keratin, type I cytoskeletal 13

1

20

High-throughput

0.621

High

1055191

K1H2
Keratin, type I cuticular Ha2

1

20

High-throughput

0.621

High

1101631

K1C24
Keratin, type I cytoskeletal 24

1

20

High-throughput

0.621

High

1149217

K1C40
Keratin, type I cytoskeletal 40

1

20

High-throughput

0.621

High

1189686

K1C26
Keratin, type I cytoskeletal 26

1

20

High-throughput

0.621

High

980286

K1C17
Keratin, type I cytoskeletal 17

1

20

High-throughput

0.618

High

504385

HSP7C
Heat shock cognate 71 kDa protein

2

3

High-throughput

0.611

High

1231039

CN119
Uncharacterized protein C14orf119

2

1

High-throughput

0.606

High

1231030

TRI54
Tripartite motif-containing protein 54

2

20

High-throughput

0.553

High

155039

NDC80
Kinetochore protein NDC80 homolog

1

20

High-throughput

0.536

High

300929

HAUS5
HAUS augmin-like complex subunit 5

1

1

High-throughput

0.536

High

847848

BRCA2
Breast cancer type 2 susceptibility protein

1

1

High-throughput

0.536

High

885274

EPIPL
Epiplakin

1

20

High-throughput

0.536

High

982264

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1017323

BPTF
Nucleosome-remodeling factor subunit BPTF

1

15

High-throughput

0.536

High

1041394

CUL2
Cullin-2

1

20

High-throughput

0.536

High

1042014

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1061167

NUMA1
Nuclear mitotic apparatus protein 1

1

8

High-throughput

0.536

High

1068595

PLEC
Plectin

1

19

High-throughput

0.536

High

1170114

FA83H
Protein FAM83H

1

6

High-throughput

0.536

High

1231027

CSN5
COP9 signalosome complex subunit 5

1

17

High-throughput

0.536

High

1220742

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

4

High-throughput

0.515

High

915435

ACTA
Actin, aortic smooth muscle

1

0

High-throughput

0.513

High

1074368

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.513

High

1231023

KNL1
Kinetochore scaffold 1

1

0

High-throughput

0.513

High

1231035

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.513

High

942791

SRPK2
SRSF protein kinase 2

1

3

High-throughput

0.501

High

1231042

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

10

Small-scale

0.501

High

1000199

IFFO1
Non-homologous end joining factor IFFO1

1

19

High-throughput

0.489

High

1062765

FL2D
Pre-mRNA-splicing regulator WTAP

1

8

High-throughput

0.489

High

1101051

QSER1
Glutamine and serine-rich protein 1

1

2

High-throughput

0.489

High

1231036

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

15

High-throughput

0.489

High

134121

DDX3X
ATP-dependent RNA helicase DDX3X

1

6

Small-scale

0.479

High

282695

RNF8
E3 ubiquitin-protein ligase RNF8

1

15

High-throughput

0.479

High

299417

UBXN7
UBX domain-containing protein 7

1

5

High-throughput

0.479

High

322872

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

325805

LATS1
Serine/threonine-protein kinase LATS1

1

8

High-throughput

0.479

High

387086

P53
Cellular tumor antigen p53

1

9

Small-scale

0.479

High

453476

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

8

High-throughput

0.479

High

529396

CFTR
Cystic fibrosis transmembrane conductance regulator

1

18

High-throughput

0.479

High

802658

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

850113

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

10

High-throughput

0.479

High

908807

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

10

High-throughput

0.479

High

927293

1433Z
14-3-3 protein zeta/delta

1

20

Small-scale

0.479

High

1065961

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

16

High-throughput

0.479

High

1163748

RICTR
Rapamycin-insensitive companion of mTOR

1

6

High-throughput

0.479

High

1231028

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

8

Small-scale

0.479

High

1231029

ACE2
Angiotensin-converting enzyme 2

1

7

High-throughput

0.479

High

1231033

CCDC8
Coiled-coil domain-containing protein 8

1

4

High-throughput

0.479

High

1231034

RN208
RING finger protein 208

1

20

Small-scale

0.479

High

1231037

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

11

High-throughput

0.479

High

1231038

ANLN
Anillin

1

12

High-throughput

0.479

High

1231041

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

1231043

MRCKB
Serine/threonine-protein kinase MRCK beta

1

2

High-throughput

0.479

High

129795

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.458

High

369983

ESR1
Estrogen receptor

1

16

High-throughput

0.445

High

891219

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

958726

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

8

High-throughput

0.445

High

1130313

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

High-throughput

0.445

High

1231031

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

20

High-throughput

0.445

High

347308

MYC
Myc proto-oncogene protein

1

14

High-throughput

0.437

High

379605

MYCN
N-myc proto-oncogene protein

1

14

High-throughput

0.437

High

569873

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.437

High

1018578

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.437

High

1046103

DX39B
Spliceosome RNA helicase DDX39B

1

20

High-throughput

0.437

High

1059730

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.437

High

1166840

LRC31
Leucine-rich repeat-containing protein 31

1

10

High-throughput

0.437

High

1170782

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1204783

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.437

High

1231026

HDAC2
Histone deacetylase 2

1

13

High-throughput

0.437

High

1231032

DDX24
ATP-dependent RNA helicase DDX24

1

20

High-throughput

0.437

High

1084

SIM26
Small integral membrane protein 26

1

7

High-throughput

0.407

High

1047159

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.407

High

1231021

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.407

High

1231022

MOT11
Monocarboxylate transporter 11

1

4

High-throughput

0.407

High

1231024

ESR2
Estrogen receptor beta

1

16

High-throughput

0.407

High

1231040

Q9NZ47
HCG1811444

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024