Protein: SESN3
Sestrin-3 (EC 1.11.1.-)

Gene: SESN3
Organism: Homo sapiens
Interactions: 10
UniProt ID: P58005

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016239 - positive regulation of macroautophagy
GO:0016684 - oxidoreductase activity, acting on peroxide as acceptor
GO:0031932 - TORC2 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

287894

MYCB2
E3 ubiquitin-protein ligase MYCBP2

3

0

High-throughput

0.638

High

945689

ZFP1
Zinc finger protein 1 homolog

3

0

High-throughput

0.638

High

945691

WDR24
GATOR2 complex protein WDR24

2

6

Small-scale

0.624

High

945687

NPRL3
GATOR1 complex protein NPRL3

1

1

Small-scale

0.550

High

945690

WDR59
GATOR2 complex protein WDR59

1

6

Small-scale

0.550

High

945688

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.513

High

945693

MIOS
GATOR2 complex protein MIOS

1

5

Small-scale

0.501

High

241236

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

945692

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.458

High

945686

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025