Protein: MIOS
GATOR2 complex protein MIOS (Missing oocyte meiosis regulator homolog)

Gene: MIOS
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q9NXC5

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1402133

WDR24
GATOR2 complex protein WDR24

9

15

Small-scale

0.973

High

938297

SEC13
Protein SEC13 homolog

6

20

Small-scale

0.950

High

1245338

WDR59
GATOR2 complex protein WDR59

4

19

Small-scale

0.886

High

1388911

SEH1
Nucleoporin SEH1

2

20

Small-scale

0.789

High

1356208

CAST1
Cytosolic arginine sensor for mTORC1 subunit 1

7

3

Small-scale

0.746

High

945684

SESN2
Sestrin-2

5

5

Small-scale

0.723

High

1145543

RBBP5
Retinoblastoma-binding protein 5

1

7

High-throughput

0.691

High

1257260

RFPLB
Ret finger protein-like 4B

4

2

High-throughput

0.691

High

1272300

DOK3
Docking protein 3

4

1

High-throughput

0.691

High

290382

RFPL2
Ret finger protein-like 2

3

2

High-throughput

0.667

High

1451958

KLH20
Kelch-like protein 20

3

2

High-throughput

0.667

High

271376

DEPD5
GATOR1 complex protein DEPDC5

3

4

Small-scale

0.656

High

253991

LPXN
Leupaxin

2

1

High-throughput

0.628

High

1407598

TCPH
T-complex protein 1 subunit eta

2

20

High-throughput

0.628

High

1007796

RAE1L
mRNA export factor RAE1

1

9

High-throughput

0.618

High

1451950

MIOS
GATOR2 complex protein MIOS

1

8

Small-scale

0.618

High

65855

CAST2
Cytosolic arginine sensor for mTORC1 subunit 2

2

3

Small-scale

0.611

High

303198

RGS20
Regulator of G-protein signaling 20

2

1

High-throughput

0.611

High

1311530

BBS7
BBSome complex member BBS7

2

0

High-throughput

0.602

High

1447143

PFD4
Prefoldin subunit 4

2

0

High-throughput

0.602

High

1007312

TCPB
T-complex protein 1 subunit beta

2

20

High-throughput

0.601

High

1451961

SESN1
Sestrin-1

1

5

Small-scale

0.586

High

902108

RAB9A
Ras-related protein Rab-9A

2

4

High-throughput

0.584

High

1272164

RRAGA
Ras-related GTP-binding protein A

2

4

Small-scale

0.584

High

1356194

NPRL2
GATOR1 complex protein NPRL2

2

4

Small-scale

0.584

High

1438001

RRAGC
Ras-related GTP-binding protein C

2

4

Small-scale

0.584

High

1451956

FAF1
FAS-associated factor 1

2

2

High-throughput

0.584

High

1451960

KPTN
KICSTOR complex protein kaptin

2

1

Small-scale

0.584

High

1063883

LG3BP
Galectin-3-binding protein

2

3

High-throughput

0.574

High

343079

HERC2
E3 ubiquitin-protein ligase HERC2

2

7

High-throughput

0.571

High

397070

ESR1
Estrogen receptor

2

14

High-throughput

0.571

High

1392939

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

0

High-throughput

0.536

High

625848

RXRA
Retinoic acid receptor RXR-alpha

1

12

High-throughput

0.536

High

1211542

SZT2
KICSTOR complex protein SZT2

1

1

Small-scale

0.536

High

1384139

ARRD3
Arrestin domain-containing protein 3

1

1

High-throughput

0.536

High

1435363

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.536

High

1451951

AIPL1
Aryl-hydrocarbon-interacting protein-like 1

1

1

High-throughput

0.536

High

1451959

PKHM1
Pleckstrin homology domain-containing family M member 1

1

1

Small-scale

0.536

High

1400289

RN157
E3 ubiquitin ligase RNF157

1

0

High-throughput

0.513

High

1429992

SHRPN
Sharpin

1

0

High-throughput

0.513

High

1451953

PLAT4
Phospholipase A and acyltransferase 4

1

0

High-throughput

0.513

High

945693

SESN3
Sestrin-3

1

5

Small-scale

0.501

High

482269

PAEP
Glycodelin

1

1

High-throughput

0.489

High

130632

SPT5H
Transcription elongation factor SPT5

1

4

High-throughput

0.479

High

243116

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

303022

PDE5A
cGMP-specific 3',5'-cyclic phosphodiesterase

1

1

High-throughput

0.479

High

342048

CEP43
Centrosomal protein 43

1

1

High-throughput

0.479

High

540709

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

Small-scale

0.479

High

560539

IFM1
Interferon-induced transmembrane protein 1

1

4

High-throughput

0.479

High

562448

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

901613

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.479

High

905204

MECP2
Methyl-CpG-binding protein 2

1

7

High-throughput

0.479

High

926421

BLM
RecQ-like DNA helicase BLM

1

4

High-throughput

0.479

High

1031565

IFM3
Interferon-induced transmembrane protein 3

1

4

High-throughput

0.479

High

1091910

NPRL3
GATOR1 complex protein NPRL3

1

2

Small-scale

0.479

High

1108214

SQSTM
Sequestosome-1

1

3

High-throughput

0.479

High

1114454

CUL3
Cullin-3

1

15

High-throughput

0.479

High

1255816

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

1324093

RHG24
Rho GTPase-activating protein 24

1

2

High-throughput

0.479

High

1329905

SIR6
NAD-dependent protein deacylase sirtuin-6

1

6

High-throughput

0.479

High

1367422

ESR2
Estrogen receptor beta

1

14

High-throughput

0.479

High

1371974

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

2

High-throughput

0.479

High

1434054

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

1438125

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

1

1

High-throughput

0.479

High

1451952

HECW2
E3 ubiquitin-protein ligase HECW2

1

7

High-throughput

0.479

High

1451954

PPM1H
Protein phosphatase 1H

1

1

High-throughput

0.479

High

664910

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

2

High-throughput

0.445

High

756375

MCM7
DNA replication licensing factor MCM7

1

3

Small-scale

0.445

High

882194

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.445

High

1434816

ZN576
Zinc finger protein 576

1

2

High-throughput

0.445

High

1451957

CLC11
C-type lectin domain family 11 member A

1

1

High-throughput

0.445

High

412702

NTRK1
High affinity nerve growth factor receptor

1

13

High-throughput

0.437

High

1211903

FKB15
FK506-binding protein 15

1

6

High-throughput

0.437

High

1451955

HECD1
E3 ubiquitin-protein ligase HECTD1

1

9

High-throughput

0.437

High

75587

B3KSW4
Regulator of G protein signaling 20

1

1

High-throughput

0.407

High

1397275

TAFA4
Chemokine-like protein TAFA-4

2

0

High-throughput

0.328

High

1103110

MFAP5
Microfibrillar-associated protein 5

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025