Protein: MACC1
Metastasis-associated in colon cancer protein 1 (SH3 domain-containing protein 7a5)

Gene: MACC1
Organism: Homo sapiens
Interactions: 15
UniProt ID: Q6ZN28

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0008083 - growth factor activity
GO:0045944 - positive regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396372

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

692083

MARK3
MAP/microtubule affinity-regulating kinase 3

1

1

High-throughput

0.536

High

839780

EPS15
Epidermal growth factor receptor substrate 15

1

1

High-throughput

0.536

High

971676

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.536

High

1252577

MARK2
Serine/threonine-protein kinase MARK2

1

1

High-throughput

0.536

High

1070503

FCHO2
F-BAR domain only protein 2

1

0

High-throughput

0.513

High

1252579

MIB2
E3 ubiquitin-protein ligase MIB2

1

0

High-throughput

0.513

High

869496

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

0

Small-scale

0.480

High

242055

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

556169

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

582846

EZRI
Ezrin

1

0

High-throughput

0.458

High

1113472

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1252578

SRRM1
Serine/arginine repetitive matrix protein 1

1

0

High-throughput

0.458

High

563957

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

1199533

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025