Protein: ORCO
Odorant receptor coreceptor (Odorant receptor 83b)

Gene: ORCO
Organism: Drosophila melanogaster
Interactions: 67
UniProt ID: Q9VNB5

Gene Ontology (top 5):
GO:0004984 - olfactory receptor activity
GO:0005516 - calmodulin binding
GO:0005549 - odorant binding
GO:0005886 - plasma membrane
GO:0005929 - cilium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1482537

ORCO
Odorant receptor coreceptor

3

5

Small-scale

0.854

High

1010827

OR22A
Odorant receptor 22a

3

5

Small-scale

0.840

High

1010830

OR43A
Odorant receptor 43a

2

5

Small-scale

0.804

High

1471742

OR92A
Putative odorant receptor 92a

1

5

Small-scale

0.618

High

920997

ACT3
Actin-57B

1

2

Small-scale

0.479

High

54491

TRE11
Trehalose transporter 1

1

0

Small-scale

0.458

High

958899

ARF1
ADP-ribosylation factor 1

1

0

Small-scale

0.458

High

1040595

KGP24
cGMP-dependent protein kinase, isozyme 2 forms cD4/T1/T3A/T3B

1

0

Small-scale

0.458

High

1458015

BDL
Protein borderless

1

0

Small-scale

0.458

High

1473167

CAD89
Cadherin-89D

1

0

Small-scale

0.458

High

1477109

NCDN
Neurochondrin homolog

1

0

Small-scale

0.458

High

1481025

KPBB
Probable phosphorylase b kinase regulatory subunit beta

1

0

Small-scale

0.458

High

1482538

RHEB
GTP-binding protein Rheb homolog

1

0

Small-scale

0.458

High

1482539

ACSA
Acetyl-coenzyme A synthetase

1

0

Small-scale

0.458

High

1482541

ATAT1
Alpha-tubulin N-acetyltransferase 1

1

0

Small-scale

0.458

High

1482550

VA0D1
V-type proton ATPase subunit d 1

1

0

Small-scale

0.458

High

534487

ACT1
Actin-5C

1

2

Small-scale

0.437

High

1173963

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

1

Small-scale

0.437

High

1176782

CP6A8
Cytochrome P450 6a8

1

2

Small-scale

0.437

High

1464221

A36DE
Accessory gland protein Acp36DE

1

1

Small-scale

0.437

High

1464980

C28A5
Probable cytochrome P450 28a5

1

2

Small-scale

0.437

High

1466366

C6A23
Probable cytochrome P450 6a23

1

2

Small-scale

0.437

High

1482551

TI50C
Mitochondrial import inner membrane translocase subunit TIM50-C

1

1

Small-scale

0.437

High

264642

COPB2
Coatomer subunit beta'

1

0

Small-scale

0.249

Low

369126

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

1

0

Small-scale

0.249

Low

384944

HSP26
Heat shock protein 26

1

0

Small-scale

0.249

Low

444128

TBA2
Tubulin alpha-2 chain

1

0

Small-scale

0.249

Low

617905

NU5M
NADH-ubiquinone oxidoreductase chain 5

1

0

Small-scale

0.249

Low

627101

CYB5R
Cytochrome b5-related protein

1

0

Small-scale

0.249

Low

628968

OTE
Otefin

1

0

Small-scale

0.249

Low

790130

DYHC
Dynein heavy chain, cytoplasmic

1

0

Small-scale

0.249

Low

808461

RSSA
Small ribosomal subunit protein uS2

1

0

Small-scale

0.249

Low

834827

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

0

Small-scale

0.249

Low

874400

RS25
Small ribosomal subunit protein eS25

1

0

Small-scale

0.249

Low

928940

EAS
Ethanolamine kinase

1

0

Small-scale

0.249

Low

939752

CDS
Phosphatidate cytidylyltransferase, photoreceptor-specific

1

0

Small-scale

0.249

Low

1014845

H2A
Histone H2A

1

0

Small-scale

0.249

Low

1017388

ATP8
ATP synthase protein 8

1

0

Small-scale

0.249

Low

1026958

MDR65
Multidrug resistance protein homolog 65

1

0

Small-scale

0.249

Low

1067082

UGGG
UDP-glucose:glycoprotein glucosyltransferase

1

0

Small-scale

0.249

Low

1070027

RS11
Small ribosomal subunit protein uS17

1

0

Small-scale

0.249

Low

1172805

SLY1
Protein sly1 homolog

1

0

Small-scale

0.249

Low

1265177

DCTN2
Dynactin subunit 2

1

0

Small-scale

0.249

Low

1270233

MMSA
Probable methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

1

0

Small-scale

0.249

Low

1285728

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

0

Small-scale

0.249

Low

1344355

NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

1

0

Small-scale

0.249

Low

1374487

HDAC1
Histone deacetylase HDAC1

1

0

Small-scale

0.249

Low

1458033

SRPRA
Signal recognition particle receptor subunit alpha homolog

1

0

Small-scale

0.249

Low

1463887

SEC13
Protein SEC13 homolog

1

0

Small-scale

0.249

Low

1466380

SAM50
SAM50-like protein CG7639

1

0

Small-scale

0.249

Low

1466919

HEMH
Ferrochelatase, mitochondrial

1

0

Small-scale

0.249

Low

1468134

CISD2
CDGSH iron-sulfur domain protein

1

0

Small-scale

0.249

Low

1468148

SERC
Phosphoserine aminotransferase

1

0

Small-scale

0.249

Low

1468952

GRASS
Serine protease grass

1

0

Small-scale

0.249

Low

1473321

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

0

Small-scale

0.249

Low

1480907

SYAC
Alanine--tRNA ligase, cytoplasmic

1

0

Small-scale

0.249

Low

1482540

AIFM1
Putative apoptosis-inducing factor 1, mitochondrial

1

0

Small-scale

0.249

Low

1482542

NPLP2
Neuropeptide-like 2

1

0

Small-scale

0.249

Low

1482543

PGM
Phosphoglucomutase 1

1

0

Small-scale

0.249

Low

1482544

PA1B2
Platelet-activating factor acetylhydrolase IB subunit beta homolog

1

0

Small-scale

0.249

Low

1482545

MUL1
Mitochondrial E3 ubiquitin protein ligase 1

1

0

Small-scale

0.249

Low

1482546

GALE
UDP-glucose 4-epimerase

1

0

Small-scale

0.249

Low

1482547

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

Small-scale

0.249

Low

1482548

PPT1
Palmitoyl-protein thioesterase 1

1

0

Small-scale

0.249

Low

1482549

UBP30
Ubiquitin carboxyl-terminal hydrolase 30 homolog

1

0

Small-scale

0.249

Low

1482552

DHRS7
Dehydrogenase/reductase SDR family protein 7-like

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025