HitPredict - High confidence protein-protein interactions

Protein: SIX6
Homeobox protein SIX6 (Homeodomain protein OPTX2) (Optic homeobox 2) (Sine oculis homeobox homolog 6)

Gene: SIX6
Organism: Homo sapiens
Interactions: 8
UniProt ID: O95475

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001654 - eye development
GO:0005634 - nucleus

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
333891	SIX3 Homeobox protein SIX3	1	20	High-throughput	0.691	High
337924	TLE1 Transducin-like enhancer protein 1	2	20	Small-scale	0.626	High
337927	TLE5 TLE family member 5	2	20	Small-scale	0.626	High
337925	TLE3 Transducin-like enhancer protein 3	1	20	High-throughput	0.536	High
337926	TLE4 Transducin-like enhancer protein 4	1	20	High-throughput	0.536	High
337928	TF2AY TFIIA-alpha and beta-like factor	1	1	High-throughput	0.494	High
273035	CLU Clustered mitochondria protein homolog	1	4	High-throughput	0.489	High
337923	SPB8 Serpin B8	1	0	High-throughput	0.279	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025