Protein: SYWM
Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS)

Gene: SYWM, WARS2
Organism: Homo sapiens
Interactions: 27
UniProt ID: Q9UGM6

Gene Ontology (top 5):
GO:0001570 - vasculogenesis
GO:0004830 - tryptophan-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1162610

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

3

3

Small-scale

0.640

High

1436200

RMD5A
E3 ubiquitin-protein transferase RMND5A

3

0

High-throughput

0.638

High

1310500

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

423394

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

279964

CISY
Citrate synthase, mitochondrial

1

1

High-throughput

0.479

High

471306

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

3

High-throughput

0.479

High

519262

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.479

High

589955

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

696778

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

769430

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

829002

MDHM
Malate dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

852069

EFTS
Elongation factor Ts, mitochondrial

1

1

High-throughput

0.479

High

856420

IF2M
Translation initiation factor IF-2, mitochondrial

1

2

High-throughput

0.479

High

1048748

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

High-throughput

0.479

High

1087610

GRSF1
G-rich sequence factor 1

1

3

High-throughput

0.479

High

1123473

ICT1
Large ribosomal subunit protein mL62

1

1

High-throughput

0.479

High

1138723

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

1142700

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.479

High

1234563

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.479

High

1381767

FAKD4
FAST kinase domain-containing protein 4

1

3

High-throughput

0.479

High

1388304

RRFM
Ribosome-recycling factor, mitochondrial

1

2

High-throughput

0.479

High

1401652

EFGM
Elongation factor G, mitochondrial

1

6

High-throughput

0.479

High

1415704

TR61B
tRNA

1

1

High-throughput

0.479

High

282123

MPPB
Mitochondrial-processing peptidase subunit beta

1

0

High-throughput

0.458

High

409114

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.458

High

1431992

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1453971

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High


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Last updated: 11Aug2025