Protein: SAHH3
Adenosylhomocysteinase 3 (AdoHcyase 3) (EC 3.13.2.1) (IP(3)Rs binding protein released with IP(3) 2) (IRBIT2) (Long-IRBIT) (S-adenosyl-L-homocysteine hydrolase 3) (S-adenosylhomocysteine hydrolase-like protein 2)

Gene: SAHH3, AHCYL2
Organism: Homo sapiens
Interactions: 134
UniProt ID: Q96HN2

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0006730 - one-carbon metabolic process
GO:0016787 - hydrolase activity
GO:0033353 - S-adenosylmethionine cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

216564

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

3

10

High-throughput

0.861

High

1250893

JOS2
Josephin-2

4

4

High-throughput

0.694

High

617884

SAHH
Adenosylhomocysteinase

1

10

High-throughput

0.691

High

1055449

DHX8
ATP-dependent RNA helicase DHX8

3

1

High-throughput

0.667

High

1134928

SYT6
Synaptotagmin-6

3

3

High-throughput

0.667

High

1256936

DOK4
Docking protein 4

3

1

High-throughput

0.667

High

302650

FA13A
Protein FAM13A

3

6

High-throughput

0.650

High

1293645

UNKL
Putative E3 ubiquitin-protein ligase UNKL

3

0

High-throughput

0.638

High

669446

EF1D
Elongation factor 1-delta

2

1

High-throughput

0.628

High

678574

MK04
Mitogen-activated protein kinase 4

2

3

High-throughput

0.628

High

686034

ARRB2
Beta-arrestin-2

2

1

High-throughput

0.628

High

817727

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

6

High-throughput

0.628

High

942436

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

2

6

High-throughput

0.628

High

1253112

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

2

6

High-throughput

0.628

High

1293633

HEXI2
Protein HEXIM2

2

4

High-throughput

0.628

High

1293637

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

2

6

High-throughput

0.628

High

1293654

CEP72
Centrosomal protein of 72 kDa

2

2

High-throughput

0.628

High

1293658

FBW1B
F-box/WD repeat-containing protein 11

2

4

High-throughput

0.628

High

1241305

CAMKV
CaM kinase-like vesicle-associated protein

3

1

High-throughput

0.616

High

660664

GRN
Progranulin

2

1

High-throughput

0.611

High

679009

HXC9
Homeobox protein Hox-C9

3

8

High-throughput

0.609

High

885454

VSX2
Visual system homeobox 2

3

4

High-throughput

0.609

High

1198916

RBM23
Probable RNA-binding protein 23

3

4

High-throughput

0.609

High

1221432

ZC3H3
Zinc finger CCCH domain-containing protein 3

3

3

High-throughput

0.609

High

1229752

ZN444
Zinc finger protein 444

3

4

High-throughput

0.609

High

1242874

FA13C
Protein FAM13C

3

4

High-throughput

0.609

High

1293636

PITX2
Pituitary homeobox 2

3

4

High-throughput

0.609

High

1205415

KI18B
Kinesin-like protein KIF18B

2

0

High-throughput

0.602

High

547179

EZRI
Ezrin

2

2

High-throughput

0.584

High

915894

RHOB
Rho-related GTP-binding protein RhoB

2

9

High-throughput

0.584

High

161864

ZN263
Zinc finger protein 263

2

1

High-throughput

0.574

High

259375

DUS11
RNA/RNP complex-1-interacting phosphatase

2

7

High-throughput

0.574

High

567873

HXB9
Homeobox protein Hox-B9

2

7

High-throughput

0.574

High

568037

HXB6
Homeobox protein Hox-B6

2

4

High-throughput

0.574

High

834102

CLK3
Dual specificity protein kinase CLK3

2

7

High-throughput

0.574

High

952853

FOXK1
Forkhead box protein K1

2

9

High-throughput

0.574

High

964229

FOXK2
Forkhead box protein K2

2

9

High-throughput

0.574

High

1021202

FOXD4
Forkhead box protein D4

2

9

High-throughput

0.574

High

1190914

TAFA3
Chemokine-like protein TAFA-3

2

1

High-throughput

0.574

High

1216193

TF2LY
Homeobox protein TGIF2LY

2

1

High-throughput

0.574

High

1232269

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

2

1

High-throughput

0.574

High

1238488

BANP
Protein BANP

2

1

High-throughput

0.574

High

1293632

ZN414
Zinc finger protein 414

2

1

High-throughput

0.574

High

1293635

RSLAB
Ras-like protein family member 10B

2

3

High-throughput

0.574

High

1293638

SOST
Sclerostin

2

1

High-throughput

0.574

High

1293641

NUAK2
NUAK family SNF1-like kinase 2

2

3

High-throughput

0.574

High

1293655

IKBL1
NF-kappa-B inhibitor-like protein 1

2

1

High-throughput

0.574

High

1293657

ABCF2
ATP-binding cassette sub-family F member 2

2

1

High-throughput

0.574

High

830451

KC1E
Casein kinase I isoform epsilon

1

2

High-throughput

0.536

High

964044

SRSF2
Serine/arginine-rich splicing factor 2

1

1

High-throughput

0.536

High

1147412

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

6

High-throughput

0.536

High

1293634

ZN641
Zinc finger protein 641

1

3

High-throughput

0.536

High

1293649

CAN10
Calpain-10

1

1

High-throughput

0.536

High

1293650

PAK6
Serine/threonine-protein kinase PAK 6

1

3

High-throughput

0.536

High

1293651

PKHJ1
Pleckstrin homology domain-containing family J member 1

1

4

High-throughput

0.536

High

1293659

FBW1A
F-box/WD repeat-containing protein 1A

1

3

High-throughput

0.536

High

1293660

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

2

High-throughput

0.536

High

1251224

WDR48
WD repeat-containing protein 48

1

6

High-throughput

0.515

High

1267086

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.515

High

1293653

DACT1
Dapper homolog 1

1

0

High-throughput

0.513

High

1293661

CAB39
Calcium-binding protein 39

1

0

High-throughput

0.513

High

239382

CC14B
Dual specificity protein phosphatase CDC14B

1

8

High-throughput

0.489

High

317852

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

1

3

High-throughput

0.489

High

402350

JUN
Transcription factor Jun

1

9

High-throughput

0.489

High

595624

HXA5
Homeobox protein Hox-A5

1

5

High-throughput

0.489

High

817024

TFPI2
Tissue factor pathway inhibitor 2

1

1

High-throughput

0.489

High

833796

CLK1
Dual specificity protein kinase CLK1

1

7

High-throughput

0.489

High

899663

FGF12
Fibroblast growth factor 12

1

3

High-throughput

0.489

High

941946

PITX1
Pituitary homeobox 1

1

4

High-throughput

0.489

High

985245

HME1
Homeobox protein engrailed-1

1

3

High-throughput

0.489

High

1021082

FOXF2
Forkhead box protein F2

1

9

High-throughput

0.489

High

1176351

KNDC1
Kinase non-catalytic C-lobe domain-containing protein 1

1

2

High-throughput

0.489

High

1223360

CA174
UPF0688 protein C1orf174

1

1

High-throughput

0.489

High

1231745

AN36B
Ankyrin repeat domain-containing protein 36B

1

1

High-throughput

0.489

High

1238335

SYT2
Synaptotagmin-2

1

3

High-throughput

0.489

High

1246259

MB3L2
Methyl-CpG-binding domain protein 3-like 2

1

1

High-throughput

0.489

High

1272799

FGF11
Fibroblast growth factor 11

1

3

High-throughput

0.489

High

1293640

WDR33
pre-mRNA 3' end processing protein WDR33

1

2

High-throughput

0.489

High

1293643

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

2

High-throughput

0.489

High

1293646

CLK4
Dual specificity protein kinase CLK4

1

7

High-throughput

0.489

High

1293647

PKHA2
Pleckstrin homology domain-containing family A member 2

1

1

High-throughput

0.489

High

1293656

DKK2
Dickkopf-related protein 2

1

1

High-throughput

0.489

High

163142

XPO1
Exportin-1

1

2

High-throughput

0.479

High

200895

CTIF
CBP80/20-dependent translation initiation factor

1

1

High-throughput

0.479

High

228352

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

350449

RASK
GTPase KRas

1

4

High-throughput

0.479

High

508149

FGFR1
Fibroblast growth factor receptor 1

1

11

High-throughput

0.479

High

573854

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.479

High

741082

ZEB1
Zinc finger E-box-binding homeobox 1

1

1

Small-scale

0.479

High

894310

CDC42
Cell division control protein 42 homolog

1

10

High-throughput

0.479

High

901220

RND3
Rho-related GTP-binding protein RhoE

1

13

High-throughput

0.479

High

925517

RAC1
Ras-related C3 botulinum toxin substrate 1

1

8

High-throughput

0.479

High

974974

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1064599

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1070342

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.479

High

1071678

KS6A2
Ribosomal protein S6 kinase alpha-2

1

2

High-throughput

0.479

High

1183504

RHOU
Rho-related GTP-binding protein RhoU

1

10

High-throughput

0.479

High

1272532

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.479

High

1293648

RHOF
Rho-related GTP-binding protein RhoF

1

11

High-throughput

0.479

High

1293662

TRAF6
TNF receptor-associated factor 6

1

3

High-throughput

0.479

High

890347

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

891972

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.458

High

674506

UFO
Tyrosine-protein kinase receptor UFO

1

8

High-throughput

0.457

High

497443

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

1222517

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.445

High

101066

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

205832

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

303421

HEXI1
Protein HEXIM1

1

4

High-throughput

0.437

High

338836

EGFR
Epidermal growth factor receptor

1

6

High-throughput

0.437

High

670158

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.437

High

872689

EPHA4
Ephrin type-A receptor 4

1

6

High-throughput

0.437

High

1081566

NTRK3
NT-3 growth factor receptor

1

7

High-throughput

0.437

High

1087923

PTN21
Tyrosine-protein phosphatase non-receptor type 21

1

8

High-throughput

0.437

High

1153723

STYK1
Tyrosine-protein kinase STYK1

1

8

High-throughput

0.437

High

1171236

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1193287

Q7Z7N5
ubiquitinyl hydrolase 1

1

4

High-throughput

0.437

High

1231302

RHG24
Rho GTPase-activating protein 24

1

4

High-throughput

0.437

High

1241827

ZBT44
Zinc finger and BTB domain-containing protein 44

1

2

High-throughput

0.437

High

1283030

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

483712

CT456
Cancer/testis antigen family 45 member A6

1

1

High-throughput

0.407

High

1148053

MSL1
Male-specific lethal 1 homolog

3

0

High-throughput

0.347

High

313652

ZIC2
Zinc finger protein ZIC 2

2

0

High-throughput

0.328

High

1089440

ODAPH
Odontogenesis associated phosphoprotein

2

0

High-throughput

0.328

High

1125758

ARSI
Arylsulfatase I

2

0

High-throughput

0.328

High

1191333

SNX20
Sorting nexin-20

2

0

High-throughput

0.328

High

1293639

PDD2L
Programmed cell death protein 2-like

2

0

High-throughput

0.328

High

1293652

BCD1
Box C/D snoRNA protein 1

2

0

High-throughput

0.328

High

49615

LNP1
Leukemia NUP98 fusion partner 1

1

0

High-throughput

0.279

Low

254821

COBL
Protein cordon-bleu

1

0

High-throughput

0.279

Low

1055971

ZN460
Zinc finger protein 460

1

0

High-throughput

0.279

Low

1293642

IKZF4
Zinc finger protein Eos

1

0

High-throughput

0.279

Low

1293644

GREM2
Gremlin-2

1

0

High-throughput

0.279

Low

648851

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

1230327

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024