Protein: IP3KB
Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B)

Gene: IP3KB, ITPKB
Organism: Homo sapiens
Interactions: 22
UniProt ID: P27987

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0000828 - inositol hexakisphosphate kinase activity
GO:0002262 - myeloid cell homeostasis
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

699920

PP2BA
Protein phosphatase 3 catalytic subunit alpha

2

3

High-throughput

0.606

High

699930

TRI54
Tripartite motif-containing protein 54

2

1

High-throughput

0.606

High

699917

1433B
14-3-3 protein beta/alpha

2

2

High-throughput

0.601

High

300306

KRT34
Keratin, type I cuticular Ha4

2

0

High-throughput

0.580

High

699923

IFT88
Intraflagellar transport protein 88 homolog

2

0

High-throughput

0.580

High

699926

SCAI
Protein SCAI

2

0

High-throughput

0.580

High

699927

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.580

High

699931

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

2

0

High-throughput

0.580

High

699933

UBQL2
Ubiquilin-2

2

0

High-throughput

0.580

High

698203

PDE4A
3',5'-cyclic-AMP phosphodiesterase 4A

1

1

High-throughput

0.536

High

699919

1433G
14-3-3 protein gamma

1

2

High-throughput

0.536

High

578388

BRAF
Serine/threonine-protein kinase B-raf

1

0

High-throughput

0.525

High

699918

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.518

High

699924

ADNP2
Activity-dependent neuroprotector homeobox protein 2

1

0

High-throughput

0.513

High

699928

PIBF1
Progesterone-induced-blocking factor 1

1

0

High-throughput

0.513

High

699916

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.480

High

403841

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

699922

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

1

High-throughput

0.479

High

699925

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

699929

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

699921

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.334

High

699932

ESF1
ESF1 homolog

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025