Protein: ASTE1
Single-strand DNA endonuclease ASTE1 (EC 3.1.-.-) (Protein asteroid homolog 1)

Gene: ASTE1
Organism: Homo sapiens
Interactions: 15
UniProt ID: Q2TB18

Gene Ontology (top 5):
GO:0000014 - single-stranded DNA endodeoxyribonuclease activity
GO:0000724 - double-strand break repair via homologous recombination
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:1990599 - 3' overhang single-stranded DNA endodeoxyribonuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1104907

XRCC4
DNA repair protein XRCC4

1

0

High-throughput

0.549

High

1180356

SOSB2
SOSS complex subunit B2

1

0

High-throughput

0.513

High

1180357

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

2

0

High-throughput

0.328

High

1180360

ZN692
Zinc finger protein 692

2

0

High-throughput

0.328

High

1180361

ES8L2
Epidermal growth factor receptor kinase substrate 8-like protein 2

2

0

High-throughput

0.328

High

329931

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

1

0

High-throughput

0.279

Low

667891

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.279

Low

776820

MYH11
Myosin-11

1

0

High-throughput

0.279

Low

955235

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.279

Low

1180358

CC85A
Coiled-coil domain-containing protein 85A

1

0

High-throughput

0.279

Low

1180359

KI20B
Kinesin-like protein KIF20B

1

0

High-throughput

0.279

Low

1180362

TM248
Transmembrane protein 248

1

0

High-throughput

0.279

Low

1180363

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.279

Low

1180365

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

1180364

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025