Protein: PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit (EC 3.1.3.16)

Gene: PP2A2, PPH22
Organism: Saccharomyces cerevisiae S288C
Interactions: 87
UniProt ID: P23595

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000159 - protein phosphatase type 2A complex
GO:0000278 - mitotic cell cycle
GO:0000779 - condensed chromosome, centromeric region
GO:0004722 - protein serine/threonine phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

618860

TAP42
Type 2A phosphatase-associated protein 42

8

19

Small-scale

0.971

High

618820

2AAA
Protein phosphatase PP2A regulatory subunit A

8

20

Small-scale

0.969

High

618867

TIP41
Type 2A phosphatase activator TIP41

5

5

Small-scale

0.922

High

618834

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

3

20

High-throughput

0.867

High

618750

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

2

13

High-throughput

0.789

High

618869

PTPA2
Serine/threonine-protein phosphatase 2A activator 2

2

12

Small-scale

0.768

High

618856

2ABA
Protein phosphatase PP2A regulatory subunit B

14

20

Small-scale

0.761

High

618828

CDC27
Anaphase-promoting complex subunit CDC27

1

5

Small-scale

0.647

High

618849

ZDS1
Protein ZDS1

4

5

Small-scale

0.633

High

618851

RTS3
Protein phosphatase type 2A regulatory subunit RTS3

2

2

High-throughput

0.628

High

334439

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

2

1

High-throughput

0.621

High

618853

FAR11
Factor arrest protein 11

1

5

Small-scale

0.621

High

618824

SWE1
Mitosis inhibitor protein kinase SWE1

2

20

Small-scale

0.619

High

618813

SCJ1
DnaJ-related protein SCJ1

2

5

High-throughput

0.618

High

618858

RUVB1
RuvB-like protein 1

2

10

High-throughput

0.611

High

618870

RUVB2
RuvB-like protein 2

2

10

High-throughput

0.611

High

618839

SSB2
Ribosome-associated molecular chaperone SSB2

2

17

High-throughput

0.601

High

587941

HSP60
Heat shock protein 60, mitochondrial

2

12

High-throughput

0.584

High

618815

MAS5
Mitochondrial protein import protein MAS5

2

5

High-throughput

0.584

High

618862

SGO1
Shugoshin

2

1

Small-scale

0.584

High

618829

HMT1
Protein arginine N-methyltransferase 1

1

2

Small-scale

0.578

High

618854

ZDS2
Protein ZDS2

2

3

High-throughput

0.567

High

392304

H2A2
Histone H2A.2

1

5

High-throughput

0.536

High

439625

SPS1
Sporulation-specific protein 1

1

20

High-throughput

0.536

High

604501

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

5

High-throughput

0.536

High

614552

KC11
Casein kinase I homolog 1

1

14

High-throughput

0.536

High

618822

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.536

High

597200

PSA7
Probable proteasome subunit alpha type-7

1

1

High-throughput

0.515

High

597284

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.515

High

604750

PSB4
Proteasome subunit beta type-4

1

3

High-throughput

0.515

High

618809

PSA2
Proteasome subunit alpha type-2

1

1

High-throughput

0.515

High

618810

PSB6
Proteasome subunit beta type-6

1

2

High-throughput

0.515

High

618812

PSB2
Proteasome subunit beta type-2

1

1

High-throughput

0.515

High

618814

PSB3
Proteasome subunit beta type-3

1

2

High-throughput

0.515

High

618818

PSB5
Proteasome subunit beta type-5

1

2

High-throughput

0.515

High

618819

PSB7
Proteasome subunit beta type-7

1

3

High-throughput

0.515

High

618821

PSA5
Proteasome subunit alpha type-5

1

1

High-throughput

0.515

High

618840

PSA6
Proteasome subunit alpha type-6

1

1

High-throughput

0.515

High

618841

PSA4
Proteasome subunit alpha type-4

1

1

High-throughput

0.515

High

618855

ERG13
Hydroxymethylglutaryl-CoA synthase

1

1

High-throughput

0.515

High

618833

RPB11
DNA-directed RNA polymerase II subunit RPB11

1

0

High-throughput

0.513

High

618844

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.513

High

447781

CDC6
Cell division control protein 6

1

1

Small-scale

0.501

High

454895

CDC16
Anaphase-promoting complex subunit CDC16

1

8

Small-scale

0.501

High

477137

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

13

High-throughput

0.501

High

618811

MPIP
M-phase inducer phosphatase

1

1

Small-scale

0.501

High

618832

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2

1

2

Small-scale

0.501

High

618852

APC1
Anaphase-promoting complex subunit 1

1

2

Small-scale

0.501

High

618857

ESP1
Separin

1

2

Small-scale

0.501

High

618866

SCC1
Sister chromatid cohesion protein 1

1

3

Small-scale

0.501

High

378291

LEU3
3-isopropylmalate dehydrogenase

1

4

High-throughput

0.500

High

424354

PYR1
Multifunctional protein URA2

1

5

High-throughput

0.500

High

439976

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

5

High-throughput

0.500

High

562324

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

5

High-throughput

0.500

High

618808

PSA3
Proteasome subunit alpha type-3

1

0

High-throughput

0.493

High

618826

T2EA
Transcription initiation factor IIE subunit alpha

1

0

High-throughput

0.493

High

618827

T2EB
Transcription initiation factor IIE subunit beta

1

0

High-throughput

0.493

High

618831

PPME1
Protein phosphatase methylesterase 1

1

4

High-throughput

0.489

High

618830

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

1

0

Small-scale

0.480

High

454192

TBA1
Tubulin alpha-1 chain

1

8

High-throughput

0.479

High

618817

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

618825

DEF1
RNA polymerase II degradation factor 1

1

4

High-throughput

0.479

High

618848

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

618859

SIZ1
E3 SUMO-protein ligase SIZ1

1

7

High-throughput

0.479

High

618863

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

2

High-throughput

0.470

High

565259

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.460

High

598591

UTR1
NAD(+) kinase

1

0

High-throughput

0.458

High

618843

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

618823

CDC13
Cell division control protein 13

1

1

Small-scale

0.457

High

618865

APC9
Anaphase-promoting complex subunit 9

1

1

Small-scale

0.457

High

549648

BGL2
Glucan 1,3-beta-glucosidase

1

1

High-throughput

0.457

High

618847

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.457

High

618868

HSP42
Heat shock protein 42

1

2

High-throughput

0.457

High

449917

HSP73
Heat shock protein SSA3

1

15

High-throughput

0.445

High

490391

HSP71
Heat shock protein SSA1

1

15

High-throughput

0.445

High

510318

SSB1
Ribosome-associated molecular chaperone SSB1

1

17

High-throughput

0.445

High

618816

SPB4
ATP-dependent rRNA helicase SPB4

1

4

High-throughput

0.437

High

618835

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.437

High

618836

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.437

High

618845

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.437

High

618861

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

618864

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

1

High-throughput

0.437

High

618838

HSP7E
Heat shock protein SSC3, mitochondrial

1

19

High-throughput

0.407

High

618850

GPG1
Heterotrimeric G protein gamma subunit GPG1

1

0

High-throughput

0.279

Low

618842

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.261

Low

618837

AIM2
Protein AIM2

1

0

High-throughput

0.249

Low

618846

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024