Protein: APRV1
Retroviral-like aspartic protease 1 (EC 3.4.23.-) (Skin-specific retroviral-like aspartic protease) (SASPase) (Skin aspartic protease) (TPA-inducible aspartic proteinase-like protein) (TAPS)

Gene: APRV1, ASPRV1
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q53RT3

Gene Ontology (top 5):
GO:0004190 - aspartic-type endopeptidase activity
GO:0016020 - membrane
GO:0016485 - protein processing
GO:0043588 - skin development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1060267

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

2

0

High-throughput

0.585

High

1200353

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.513

High

1200354

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.513

High

552268

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.493

High

406891

MAS
Proto-oncogene Mas

1

1

High-throughput

0.489

High

485185

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

1200347

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

2

0

High-throughput

0.328

High

1200356

GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1

2

0

High-throughput

0.328

High

1200358

FCF1
rRNA-processing protein FCF1 homolog

2

0

High-throughput

0.328

High

1200357

RAB9B
Ras-related protein Rab-9B

2

0

High-throughput

0.318

High

1200355

ELMD3
ELMO domain-containing protein 3

2

0

High-throughput

0.313

High

842778

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

0

High-throughput

0.282

High

733366

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

1023795

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.279

Low

1112866

CUL2
Cullin-2

1

0

High-throughput

0.279

Low

1200349

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.279

Low

1200351

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.279

Low

1200359

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

0

Small-scale

0.261

Low

292294

B3GL1
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.249

Low

349112

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.249

Low

872397

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

888111

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.249

Low

943847

CF298
Cilia- and flagella-associated protein 298

1

0

High-throughput

0.249

Low

951704

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

High-throughput

0.249

Low

1118050

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.249

Low

1200352

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

261185

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

1200348

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low

1200350

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025