Protein: TRA1
Transcription-associated protein 1 (p400 kDa component of SAGA)

Gene: TRA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 133
UniProt ID: P38811

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0006338 - chromatin remodeling
GO:0006351 - DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

755458

EAF1
Chromatin modification-related protein EAF1

7

1

Small-scale

0.960

High

744612

TAF5
Transcription initiation factor TFIID subunit 5

4

9

High-throughput

0.895

High

755445

ADA2
Transcriptional adapter 2

17

7

Small-scale

0.764

High

755467

ESA1
Histone acetyltransferase ESA1

19

12

Small-scale

0.764

High

715324

SPT7
Transcriptional activator SPT7

19

19

Small-scale

0.764

High

755426

EPL1
Enhancer of polycomb-like protein 1

14

3

Small-scale

0.760

High

755449

GCN5
Histone acetyltransferase GCN5

14

18

Small-scale

0.760

High

755470

HFI1
Transcriptional coactivator HFI1/ADA1

13

2

Small-scale

0.758

High

755480

SUS1
Transcription and mRNA export factor SUS1

12

3

Small-scale

0.757

High

755450

TAF12
Transcription initiation factor TFIID subunit 12

12

4

Small-scale

0.756

High

755416

SPT8
Transcription factor SPT8

8

1

Small-scale

0.750

High

755435

SGF73
SAGA-associated factor 73

8

6

Small-scale

0.747

High

755456

TAF9
Transcription initiation factor TFIID subunit 9

8

4

Small-scale

0.747

High

755432

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

8

9

Small-scale

0.747

High

755434

TAF6
Transcription initiation factor TFIID subunit 6

7

4

Small-scale

0.745

High

420609

SPT3
Protein SPT3

7

3

Small-scale

0.741

High

755438

AF9
Protein AF-9 homolog

6

6

Small-scale

0.733

High

691318

NGG1
Chromatin-remodeling complexes subunit NGG1

6

3

Small-scale

0.729

High

755433

SPT20
Transcription factor SPT20

11

0

Small-scale

0.725

High

755358

YNG2
Chromatin modification-related protein YNG2

5

11

Small-scale

0.721

High

755436

SWC4
SWR1-complex protein 4

4

4

Small-scale

0.699

High

755443

ARP4
Actin-related protein 4

4

6

Small-scale

0.697

High

633859

SGF29
SAGA-associated factor 29

4

5

Small-scale

0.694

High

755477

EAF3
Chromatin modification-related protein EAF3

4

3

Small-scale

0.691

High

755419

EAF5
Chromatin modification-related protein EAF5

5

0

Small-scale

0.686

High

755437

EAF7
Chromatin modification-related protein EAF7

5

0

Small-scale

0.684

High

755447

SGF11
SAGA-associated factor 11

5

0

Small-scale

0.684

High

755469

TAF10
Transcription initiation factor TFIID subunit 10

4

3

Small-scale

0.683

High

755431

EAF6
Chromatin modification-related protein EAF6

4

0

Small-scale

0.667

High

381545

GAL4
Regulatory protein GAL4

3

1

Small-scale

0.654

High

755454

LCD1
DNA damage checkpoint protein LCD1

1

1

Small-scale

0.647

High

755423

SA185
SIT4-associating protein SAP185

2

5

High-throughput

0.628

High

368735

GCN4
General control transcription factor GCN4

3

0

Small-scale

0.623

High

698792

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

6

High-throughput

0.618

High

392423

H2A2
Histone H2A.2

2

10

Small-scale

0.611

High

707018

MSN4
Zinc finger protein MSN4

2

3

High-throughput

0.601

High

755479

H2AZ
Histone H2A.Z

2

8

Small-scale

0.601

High

687695

BTAF1
TATA-binding protein-associated factor MOT1

2

11

Small-scale

0.584

High

755414

TRA1
Transcription-associated protein 1

1

16

Small-scale

0.575

High

628028

SIS1
Protein SIS1

2

7

Small-scale

0.571

High

689876

ASF1
Histone chaperone ASF1

2

1

Small-scale

0.571

High

755441

ACT
Actin

2

1

Small-scale

0.571

High

755442

H3
Histone H3

2

9

High-throughput

0.571

High

755472

RIO1
Serine/threonine-protein kinase RIO1

2

3

High-throughput

0.571

High

743524

HMT1
Protein arginine N-methyltransferase 1

1

2

Small-scale

0.541

High

423681

ADR1
Regulatory protein ADR1

1

1

High-throughput

0.536

High

436834

SWI5
Transcriptional factor SWI5

1

4

High-throughput

0.536

High

501166

HSF
Heat shock transcription factor

1

2

High-throughput

0.536

High

745418

RTG3
Retrograde regulation protein 3

1

1

High-throughput

0.536

High

752110

KSP1
Serine/threonine-protein kinase KSP1

1

18

High-throughput

0.536

High

755446

IMA1
Importin subunit alpha

1

6

High-throughput

0.536

High

755468

CTI6
Histone deacetylase complex subunit CTI6

1

1

High-throughput

0.536

High

587850

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.513

High

755460

RSC3
Chromatin structure-remodeling complex protein RSC3

1

0

High-throughput

0.513

High

755475

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.513

High

755422

MSL1
U2 small nuclear ribonucleoprotein B''

1

5

High-throughput

0.508

High

703995

XRS2
DNA repair protein XRS2

1

1

Small-scale

0.501

High

515057

MCM1
Pheromone receptor transcription factor

1

1

Small-scale

0.481

High

565157

CBF1
Centromere-binding protein 1

1

3

Small-scale

0.481

High

755425

FKH2
Fork head protein homolog 2

1

5

Small-scale

0.481

High

755429

ZAP1
Zinc-responsive transcriptional regulator ZAP1

1

2

Small-scale

0.481

High

339618

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.479

High

392119

H2A1
Histone H2A.1

1

10

Small-scale

0.479

High

605026

XRN1
5'-3' exoribonuclease 1

1

2

High-throughput

0.479

High

607270

RFA1
Replication factor A protein 1

1

7

Small-scale

0.479

High

662164

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

667579

MCM2
DNA replication licensing factor MCM2

1

8

Small-scale

0.479

High

675524

MCM4
DNA replication licensing factor MCM4

1

9

Small-scale

0.479

High

689750

SFP1
Transcription factor SFP1

1

3

Small-scale

0.479

High

696141

SWI3
SWI/SNF complex subunit SWI3

1

7

High-throughput

0.479

High

697391

CHD1
Chromo domain-containing protein 1

1

8

Small-scale

0.479

High

732564

TTI1
TEL2-interacting protein 1

1

16

High-throughput

0.479

High

751019

RCK1
Serine/threonine-protein kinase RCK1

1

15

High-throughput

0.479

High

755421

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.479

High

755430

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

755439

APJ1
J domain-containing protein APJ1

1

8

High-throughput

0.479

High

755448

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

755452

RUVB1
RuvB-like protein 1

1

19

High-throughput

0.479

High

755453

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

755471

SCC1
Sister chromatid cohesion protein 1

1

3

High-throughput

0.479

High

755474

SMT3
Ubiquitin-like protein SMT3

1

4

High-throughput

0.479

High

599255

REB1
DNA-binding protein REB1

1

0

Small-scale

0.460

High

527003

TBP
TATA-box-binding protein

1

0

High-throughput

0.458

High

534519

HAP4
Transcriptional activator HAP4

1

0

Small-scale

0.458

High

558045

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

586304

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

Small-scale

0.458

High

688231

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

716233

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

716418

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

755415

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.458

High

755427

SAC3
Nuclear mRNA export protein SAC3

1

0

Small-scale

0.458

High

755451

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

755455

TAF7
Transcription initiation factor TFIID subunit 7

1

0

High-throughput

0.458

High

755457

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

755459

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

755466

SGO1
Shugoshin

1

0

High-throughput

0.458

High

355477

H2B1
Histone H2B.1

1

7

High-throughput

0.445

High

356463

H4
Histone H4

1

6

High-throughput

0.445

High

485519

SSBP1
Single-stranded nucleic acid-binding protein

1

2

High-throughput

0.445

High

491153

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

493913

HSP72
Heat shock protein SSA2

1

12

High-throughput

0.445

High

511240

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

514175

NHP6A
Non-histone chromosomal protein 6A

1

5

High-throughput

0.445

High

581362

MED14
Mediator of RNA polymerase II transcription subunit 14

1

1

High-throughput

0.445

High

628864

SWI4
Regulatory protein SWI4

1

3

High-throughput

0.445

High

633207

MAS5
Mitochondrial protein import protein MAS5

1

8

High-throughput

0.445

High

694656

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

705882

IXR1
Intrastrand cross-link recognition protein

1

4

High-throughput

0.445

High

706961

MSN2
Zinc finger protein MSN2

1

2

High-throughput

0.445

High

733244

SET3
SET domain-containing protein 3

1

4

High-throughput

0.445

High

755428

TRM61
tRNA

1

1

High-throughput

0.445

High

755440

CRZ1
Transcriptional regulator CRZ1

1

3

High-throughput

0.445

High

755444

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

16

High-throughput

0.445

High

755465

THP1
Nuclear mRNA export protein THP1

1

1

Small-scale

0.445

High

755476

IES3
Ino eighty subunit 3

1

1

High-throughput

0.445

High

755478

RLF2
Chromatin assembly factor 1 subunit p90

1

2

High-throughput

0.445

High

526842

DPOLA
DNA polymerase alpha catalytic subunit A

1

2

Small-scale

0.437

High

745644

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

755462

VAM6
Vacuolar morphogenesis protein 6

1

4

High-throughput

0.437

High

419336

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

755464

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

659963

MSP1
Outer mitochondrial transmembrane helix translocase

1

4

High-throughput

0.407

High

755417

TCPB
T-complex protein 1 subunit beta

1

2

High-throughput

0.407

High

755463

NOP6
Nucleolar protein 6

1

0

High-throughput

0.279

Low

755473

ATG34
Autophagy-related protein 34

1

0

High-throughput

0.279

Low

630110

ELO2
Fatty acid elongase 2

1

0

High-throughput

0.249

Low

700880

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

748133

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

755418

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

755420

ICE2
Protein ICE2

1

0

High-throughput

0.232

Low

755424

SYS1
Protein SYS1

1

0

High-throughput

0.232

Low

755461

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024