Protein: CDC73
Cell division control protein 73 (RNA polymerase-associated protein CDC73)

Gene: CDC73
Organism: Saccharomyces cerevisiae S288C
Interactions: 112
UniProt ID: Q06697

Gene Ontology (top 5):
GO:0000791 - euchromatin
GO:0000993 - RNA polymerase II complex binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006362 - transcription elongation by RNA polymerase I

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

953693

CTR9
RNA polymerase-associated protein CTR9

17

6

Small-scale

0.763

High

749009

PAF1
RNA polymerase II-associated protein 1

16

3

Small-scale

0.762

High

858844

RTF1
RNA polymerase-associated protein RTF1

14

1

Small-scale

0.761

High

750639

LEO1
RNA polymerase-associated protein LEO1

12

2

Small-scale

0.759

High

375516

RPB1
DNA-directed RNA polymerase II subunit RPB1

6

2

Small-scale

0.737

High

692940

SPT16
FACT complex subunit SPT16

9

0

Small-scale

0.719

High

988699

CDC73
Cell division control protein 73

2

0

Small-scale

0.718

High

440106

RPB2
DNA-directed RNA polymerase II subunit RPB2

4

1

Small-scale

0.692

High

558276

RPB3
DNA-directed RNA polymerase II subunit RPB3

4

1

Small-scale

0.680

High

650400

SPT5
Transcription elongation factor SPT5

3

1

Small-scale

0.670

High

663432

TF2B
Transcription initiation factor IIB

3

1

Small-scale

0.665

High

757160

RPB11
DNA-directed RNA polymerase II subunit RPB11

3

0

Small-scale

0.623

High

550131

CSK21
Casein kinase II subunit alpha

2

1

High-throughput

0.621

High

584805

CSK22
Casein kinase II subunit alpha'

2

1

High-throughput

0.621

High

586340

MED15
Mediator of RNA polymerase II transcription subunit 15

3

0

Small-scale

0.614

High

544480

HSC82
ATP-dependent molecular chaperone HSC82

3

4

High-throughput

0.604

High

492566

HSP71
Heat shock protein SSA1

2

4

High-throughput

0.601

High

979854

POB3
FACT complex subunit POB3

3

1

Small-scale

0.593

High

628510

SIS1
Protein SIS1

2

1

High-throughput

0.584

High

866504

APJ1
J domain-containing protein APJ1

2

1

High-throughput

0.571

High

693942

MED18
Mediator of RNA polymerase II transcription subunit 18

2

0

Small-scale

0.559

High

784883

T2FB
Transcription initiation factor IIF subunit beta

2

0

Small-scale

0.547

High

715740

TAF14
Transcription initiation factor TFIID subunit 14

2

2

Small-scale

0.543

High

619174

SPT6
Transcription elongation factor SPT6

1

0

Small-scale

0.537

High

495072

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.536

High

512884

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.536

High

681027

HS104
Heat shock protein 104

1

1

High-throughput

0.536

High

975974

GCN5
Histone acetyltransferase GCN5

1

2

High-throughput

0.515

High

425389

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

961928

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

Small-scale

0.506

High

410239

UBC2
Ubiquitin-conjugating enzyme E2 2

1

3

Small-scale

0.501

High

697443

CHD1
Chromo domain-containing protein 1

1

2

Small-scale

0.501

High

902093

H3
Histone H3

1

2

Small-scale

0.501

High

759455

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

812659

BCA2
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.493

High

862653

SPC98
Spindle pole body component SPC98

1

0

High-throughput

0.493

High

972919

IMA1
Importin subunit alpha

1

0

High-throughput

0.493

High

988705

RUP1
UBA domain-containing protein RUP1

1

0

High-throughput

0.493

High

705705

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.489

High

757968

CSK2C
Casein kinase II subunit beta'

1

1

High-throughput

0.489

High

798391

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.489

High

760595

SSN3
Meiotic mRNA stability protein kinase SSN3

1

2

Small-scale

0.481

High

356749

H4
Histone H4

1

1

High-throughput

0.479

High

408475

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

High-throughput

0.479

High

606770

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.479

High

655583

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

1

High-throughput

0.479

High

663920

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.479

High

710036

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

1

High-throughput

0.479

High

744172

ATR
Serine/threonine-protein kinase MEC1

1

2

Small-scale

0.479

High

755805

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

3

Small-scale

0.479

High

772491

RAD26
DNA repair and recombination protein RAD26

1

2

Small-scale

0.479

High

859281

INO80
Chromatin-remodeling ATPase INO80

1

2

Small-scale

0.479

High

984216

HRQ1
ATP-dependent helicase HRQ1

1

1

Small-scale

0.479

High

690712

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.470

High

527068

TBP
TATA-box-binding protein

1

0

Small-scale

0.460

High

561914

TUP1
General transcriptional corepressor TUP1

1

0

Small-scale

0.460

High

339863

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.458

High

568910

HPR1
THO complex subunit HPR1

1

0

Small-scale

0.458

High

593092

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.458

High

593192

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.458

High

593268

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

593348

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

604717

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.458

High

680063

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

0

Small-scale

0.458

High

688448

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

768164

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

1

0

High-throughput

0.458

High

773014

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.458

High

777146

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.458

High

784863

T2FA
Transcription initiation factor IIF subunit alpha

1

0

High-throughput

0.458

High

819915

CLA4
Serine/threonine-protein kinase CLA4

1

0

Small-scale

0.458

High

860300

TAL2
Transaldolase NQM1

1

0

High-throughput

0.458

High

865465

ELOA1
Elongin-A

1

0

Small-scale

0.458

High

986561

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

Small-scale

0.458

High

987048

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

988702

TAF10
Transcription initiation factor TFIID subunit 10

1

0

High-throughput

0.458

High

988703

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

988704

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

366961

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.445

High

450202

HSP73
Heat shock protein SSA3

1

4

High-throughput

0.445

High

695616

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

754741

SSZ1
Ribosome-associated complex subunit SSZ1

1

3

High-throughput

0.445

High

761326

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

854683

PFD6
Prefoldin subunit 6

1

1

High-throughput

0.445

High

532832

MSI1
Chromatin assembly factor 1 subunit p50

1

0

High-throughput

0.438

High

988701

RBX1
RING-box protein HRT1

1

0

High-throughput

0.438

High

979040

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.437

High

960016

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

969217

UBC7
Ubiquitin-conjugating enzyme E2 7

1

3

High-throughput

0.417

High

361043

TBB
Tubulin beta chain

1

1

High-throughput

0.407

High

424735

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.407

High

478554

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.407

High

520000

TCPA
T-complex protein 1 subunit alpha

1

4

High-throughput

0.407

High

760825

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.407

High

766231

HSP7E
Heat shock protein SSC3, mitochondrial

1

5

High-throughput

0.407

High

865499

JJJ1
J protein JJJ1

1

1

High-throughput

0.407

High

872875

ZDS2
Protein ZDS2

1

1

High-throughput

0.407

High

988585

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

1

High-throughput

0.407

High

561838

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.269

Low

752028

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.269

Low

988708

FOLD
Dihydrofolate synthetase

1

0

High-throughput

0.269

Low

634788

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

701107

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

741404

GLY1
Low specificity L-threonine aldolase

1

0

High-throughput

0.249

Low

784264

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

0

High-throughput

0.249

Low

792597

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

988700

CRT10
Protein CRT10

1

0

Small-scale

0.249

Low

541800

SEC63
Protein translocation protein SEC63

1

0

High-throughput

0.232

Low

766553

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

785234

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

988706

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low

988707

JID1
J domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024