Protein: SHR3
Secretory component protein SHR3

Gene: SHR3
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: Q02774

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006457 - protein folding
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

877848

GNP1
High-affinity glutamine permease

4

11

Small-scale

0.690

High

448263

HIP1
Histidine permease

3

11

High-throughput

0.668

High

793252

BAP2
Leu/Val/Ile amino-acid permease

3

11

Small-scale

0.668

High

618887

GAP1
General amino-acid permease GAP1

3

11

Small-scale

0.658

High

673441

AGP1
General amino acid permease AGP1

3

11

Small-scale

0.658

High

763810

CSG2
Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2

3

0

High-throughput

0.640

High

836164

BAP3
Valine amino-acid permease

2

11

High-throughput

0.614

High

416722

CAN1
Arginine permease CAN1

2

11

Small-scale

0.613

High

1038519

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

2

0

High-throughput

0.605

High

797032

PHO88
SRP-independent targeting protein 3

2

0

High-throughput

0.588

High

1038518

SHR3
Secretory component protein SHR3

2

0

High-throughput

0.588

High

803040

YHE2
Putative uncharacterized protein YHL042W

1

3

High-throughput

0.541

High

808365

TAT2
Tryptophan permease

1

11

High-throughput

0.541

High

808694

SUR2
Sphingolipid C4-hydroxylase SUR2

1

1

High-throughput

0.541

High

916772

ERG25
C-4 methylsterol oxidase ERG25

1

1

High-throughput

0.541

High

919627

TNA1
High-affinity nicotinic acid transporter

1

1

High-throughput

0.541

High

932621

TMEDA
Endoplasmic reticulum vesicle protein 25

1

1

High-throughput

0.541

High

1038531

SAM3
S-adenosylmethionine permease SAM3

1

11

High-throughput

0.541

High

1038532

MMP1
S-methylmethionine permease 1

1

11

High-throughput

0.541

High

439539

PIS
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.518

High

528627

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

High-throughput

0.518

High

735858

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.518

High

745383

EMP24
Endosomal protein P24B

1

0

High-throughput

0.518

High

754652

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

1

0

High-throughput

0.518

High

797612

YPC1
Alkaline ceramidase YPC1

1

0

High-throughput

0.518

High

798722

BSD2
Metal homeostatis protein BSD2

1

0

High-throughput

0.518

High

805904

YHU0
UPF0641 membrane protein YHR140W

1

0

High-throughput

0.518

High

805930

CHS7
Chitin synthase export chaperone

1

0

High-throughput

0.518

High

808717

FET3
Iron transport multicopper oxidase FET3

1

0

High-throughput

0.518

High

812898

SOP4
Protein SOP4

1

0

High-throughput

0.518

High

826145

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.518

High

863220

PHO86
Inorganic phosphate transporter PHO86

1

0

High-throughput

0.518

High

863277

GPI2
Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit

1

0

High-throughput

0.518

High

863336

SPC1
Signal peptidase complex subunit 1

1

0

High-throughput

0.518

High

865253

YJY5
Uncharacterized endoplasmic reticulum membrane protein YJR015W

1

0

High-throughput

0.518

High

1038524

ORM2
Protein ORM2

1

0

High-throughput

0.518

High

1038527

PMT7
Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7

1

0

High-throughput

0.518

High

745966

UGA4
GABA-specific permease

1

11

High-throughput

0.494

High

747200

PMP1
Plasma membrane ATPase proteolipid 1

1

1

High-throughput

0.494

High

794382

MAL31
Maltose permease MAL31

1

1

High-throughput

0.494

High

803008

COS8
Protein COS8

1

3

High-throughput

0.494

High

830042

PMP2
Plasma membrane ATPase proteolipid 2

1

1

High-throughput

0.494

High

919814

COS6
Protein COS6

1

3

High-throughput

0.494

High

920730

DIP5
Dicarboxylic amino acid permease

1

11

High-throughput

0.494

High

1038525

TPO3
Polyamine transporter 3

1

2

High-throughput

0.494

High

1038530

TPO1
Polyamine transporter 1

1

2

High-throughput

0.494

High

641390

SEC62
Translocation protein SEC62

1

0

High-throughput

0.486

High

1038522

SSY1
SPS-sensor component SSY1

1

11

Small-scale

0.481

High

524912

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.479

High

527486

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.479

High

582509

SEC23
Protein transport protein SEC23

1

1

Small-scale

0.479

High

825241

SEC24
Protein transport protein SEC24

1

1

Small-scale

0.479

High

1038528

YFT2
Acyl-coenzyme A diphosphatase YFT2

1

0

Small-scale

0.460

High

545981

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.458

High

670326

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.458

High

748512

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.458

High

795505

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

808389

SEC31
Protein transport protein SEC31

1

0

Small-scale

0.458

High

1038523

SEC13
Protein transport protein SEC13

1

0

Small-scale

0.458

High

1038526

LOA1
Lysophosphatidic acid:oleoyl-CoA acyltransferase 1

1

0

High-throughput

0.458

High

511079

COS3
Protein COS3

1

3

High-throughput

0.439

High

609286

CPT1
Cholinephosphotransferase 1

1

0

High-throughput

0.438

High

1035041

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.438

High

689619

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

870675

RS7B
Small ribosomal subunit protein eS7B

1

1

High-throughput

0.437

High

1038521

YMD8
Putative nucleotide-sugar transporter YMD8

2

0

High-throughput

0.329

High

560287

KEX2
Kexin

1

0

High-throughput

0.282

High

663616

VATO
V-type proton ATPase subunit c''

1

0

High-throughput

0.282

High

687076

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

0

High-throughput

0.282

High

737243

HXT1
Low-affinity glucose transporter HXT1

1

0

High-throughput

0.282

High

898923

AVT4
Vacuolar amino acid transporter 4

1

0

High-throughput

0.282

High

1018192

PMP3
Plasma membrane proteolipid 3

1

0

High-throughput

0.282

High

1038520

GAS3
Probable 1,3-beta-glucanosyltransferase GAS3

1

0

High-throughput

0.282

High

1038529

MCH1
Probable transporter MCH1

1

0

High-throughput

0.282

High

1038533

POM34
Nucleoporin POM34

1

0

High-throughput

0.282

High

808417

HAL5
Serine/threonine-protein kinase HAL5

1

0

High-throughput

0.261

Low

432677

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.249

Low

512605

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

513753

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

531858

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.249

Low

570297

RS17B
Small ribosomal subunit protein eS17B

1

0

High-throughput

0.249

Low

601114

RL8A
Large ribosomal subunit protein eL8A

1

0

High-throughput

0.249

Low

1038534

RL13A
Large ribosomal subunit protein eL13A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025