Protein: HOLE
DNA polymerase III subunit theta (EC 2.7.7.7)

Gene: HOLE
Organism: Escherichia coli K-12
Interactions: 28
UniProt ID: P0ABS8

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005829 - cytosol
GO:0006261 - DNA-templated DNA replication
GO:0006272 - leading strand elongation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

395114

DPO3E
DNA polymerase III subunit epsilon

6

0

Small-scale

0.896

High

491055

DNAK
Chaperone protein DnaK

2

0

High-throughput

0.585

High

498558

DPO3A
DNA polymerase III subunit alpha

2

0

Small-scale

0.563

High

498566

CNOX
Chaperedoxin

2

0

High-throughput

0.563

High

498560

PEPD
Cytosol non-specific dipeptidase

1

0

High-throughput

0.513

High

498561

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

498563

HOLB
DNA polymerase III subunit delta'

1

1

High-throughput

0.484

High

382567

RS6
Small ribosomal subunit protein bS6

1

0

High-throughput

0.464

High

444293

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.464

High

445403

DPO3X
DNA polymerase III subunit tau

1

0

High-throughput

0.464

High

492485

RL7
Large ribosomal subunit protein bL12

1

0

High-throughput

0.464

High

492709

RL1
Large ribosomal subunit protein uL1

1

0

High-throughput

0.464

High

493231

RS10
Small ribosomal subunit protein uS10

1

0

High-throughput

0.464

High

498550

HNS
DNA-binding protein H-NS

1

0

High-throughput

0.464

High

498556

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

0

High-throughput

0.464

High

498559

KATG
Catalase-peroxidase

1

0

High-throughput

0.464

High

498562

HOLA
DNA polymerase III subunit delta

1

0

High-throughput

0.464

High

498564

HOLD
DNA polymerase III subunit psi

1

0

High-throughput

0.464

High

498565

HOLC
DNA polymerase III subunit chi

1

0

High-throughput

0.464

High

498555

SSB
Single-stranded DNA-binding protein

1

0

High-throughput

0.426

High

498551

YECF
Uncharacterized protein YecF

1

0

High-throughput

0.279

Low

498553

RS1
Small ribosomal subunit protein bS1

1

0

High-throughput

0.279

Low

493477

RS16
Small ribosomal subunit protein bS16

1

0

High-throughput

0.253

Low

493723

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.253

Low

498552

RL23
Large ribosomal subunit protein uL23

1

0

High-throughput

0.253

Low

498554

UGPB
sn-glycerol-3-phosphate-binding periplasmic protein UgpB

1

0

High-throughput

0.253

Low

498557

EFTU1
Elongation factor Tu 1

1

0

High-throughput

0.253

Low

489248

UBIB
Probable protein kinase UbiB

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025