Protein: TIAM2
Rho guanine nucleotide exchange factor TIAM2 (SIF and TIAM1-like exchange factor) (T-lymphoma invasion and metastasis-inducing protein 2) (TIAM-2)

Gene: TIAM2
Organism: Homo sapiens
Interactions: 14
UniProt ID: Q8IVF5

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0007264 - small GTPase-mediated signal transduction
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1308683

TNIK
TRAF2 and NCK-interacting protein kinase

2

13

High-throughput

0.743

High

627989

ANXA7
Annexin A7

1

2

High-throughput

0.656

High

896819

DYN2
Dynamin-2

1

10

High-throughput

0.656

High

1308681

SH3G2
Endophilin-A1

1

20

High-throughput

0.656

High

978138

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

1308682

DISC1
Disrupted in schizophrenia 1 protein

2

8

High-throughput

0.576

High

1008222

PRKDC
DNA-dependent protein kinase catalytic subunit

1

6

High-throughput

0.515

High

405501

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.508

High

591722

H2AX
Histone H2AX

1

0

High-throughput

0.486

High

1308679

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.486

High

358888

AL1A1
Aldehyde dehydrogenase 1A1

1

1

High-throughput

0.479

High

1308678

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

14

High-throughput

0.445

High

1308680

RING2
E3 ubiquitin-protein ligase RING2

1

4

High-throughput

0.437

High

1308684

TRRAP
Transformation/transcription domain-associated protein

1

6

High-throughput

0.437

High


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Last updated: 11Aug2025