Protein: KPYK2
Pyruvate kinase 2 (PK 2) (EC 2.7.1.40)

Gene: KPYK2, PYK2
Organism: Saccharomyces cerevisiae S288C
Interactions: 31
UniProt ID: P52489

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004743 - pyruvate kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

365114

KPYK1
Pyruvate kinase 1

2

14

High-throughput

0.737

High

441192

KAPA
cAMP-dependent protein kinase type 1

2

5

Small-scale

0.619

High

510655

HSP77
Import motor subunit, mitochondrial

2

6

High-throughput

0.571

High

524556

HSP71
Heat shock protein SSA1

2

5

High-throughput

0.552

High

393036

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.541

High

441383

KAPB
cAMP-dependent protein kinase type 2

1

4

Small-scale

0.536

High

746369

RAEP
Rab proteins geranylgeranyltransferase component A

1

1

High-throughput

0.536

High

644638

MDHC
Malate dehydrogenase, cytoplasmic

1

1

High-throughput

0.508

High

607772

HXKG
Glucokinase-1

1

2

High-throughput

0.479

High

386786

TBB
Tubulin beta chain

1

1

High-throughput

0.445

High

394718

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

453688

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

527173

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

545555

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

577178

SEC63
Protein translocation protein SEC63

1

2

High-throughput

0.445

High

676167

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

741974

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

816310

HSP7E
Heat shock protein SSC3, mitochondrial

1

6

High-throughput

0.445

High

819257

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

826455

DJP1
DnaJ-like protein 1

1

3

High-throughput

0.445

High

836784

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.445

High

574904

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.438

High

707639

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

812486

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

486252

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

592367

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

810987

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.426

High

670927

SIS1
Protein SIS1

1

3

High-throughput

0.407

High

811355

CAJ1
Protein CAJ1

1

3

High-throughput

0.407

High

795101

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

823312

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025