Protein: PSF2
DNA replication complex GINS protein PSF2 (Partner of Sld five 2)

Gene: PSF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 65
UniProt ID: P40359

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0000811 - GINS complex
GO:0005634 - nucleus
GO:0006261 - DNA-templated DNA replication
GO:0031261 - DNA replication preinitiation complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

823317

SLD5
DNA replication complex GINS protein SLD5

18

6

Small-scale

0.986

High

721379

MCM4
DNA replication licensing factor MCM4

10

11

Small-scale

0.972

High

823316

CTF4
DNA polymerase alpha-binding protein

8

1

Small-scale

0.971

High

823323

PSF1
DNA replication complex GINS protein PSF1

7

5

Small-scale

0.961

High

823320

CDC45
Cell division control protein 45

8

3

Small-scale

0.959

High

712995

MCM2
DNA replication licensing factor MCM2

7

8

Small-scale

0.954

High

664439

MCM3
DNA replication licensing factor MCM3

6

10

Small-scale

0.939

High

823322

PSF3
DNA replication complex GINS protein PSF3

5

3

Small-scale

0.925

High

794079

MCM7
DNA replication licensing factor MCM7

5

9

Small-scale

0.912

High

713270

MCM5
Minichromosome maintenance protein 5

4

12

Small-scale

0.878

High

823314

MCM6
DNA replication licensing factor MCM6

2

11

Small-scale

0.778

High

823310

DPB11
DNA replication regulator DPB11

1

1

Small-scale

0.740

High

665185

DPB2
DNA polymerase epsilon subunit B

4

1

Small-scale

0.680

High

823309

PSF2
DNA replication complex GINS protein PSF2

1

0

Small-scale

0.676

High

735384

MCM10
Minichromosome maintenance protein 10

3

1

Small-scale

0.660

High

392830

HSP82
ATP-dependent molecular chaperone HSP82

2

1

High-throughput

0.552

High

642052

DPOE
DNA polymerase epsilon catalytic subunit A

1

1

Small-scale

0.501

High

646427

RAD53
Serine/threonine-protein kinase RAD53

1

2

High-throughput

0.479

High

647779

RFA1
Replication factor A protein 1

1

0

Small-scale

0.458

High

677683

MRC1
Mediator of replication checkpoint protein 1

1

0

Small-scale

0.458

High

737879

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.458

High

776474

MPE1
Protein MPE1

1

0

Small-scale

0.458

High

823313

UFD1
Ubiquitin fusion degradation protein 1

1

0

Small-scale

0.458

High

823315

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

0

Small-scale

0.458

High

823318

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

823321

DIA2
Protein DIA2

1

0

Small-scale

0.458

High

545100

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

709798

BMH1
Protein BMH1

1

1

High-throughput

0.445

High

760272

BMH2
Protein BMH2

1

1

High-throughput

0.445

High

804204

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

561316

DPOLA
DNA polymerase alpha catalytic subunit A

1

1

Small-scale

0.437

High

366809

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.426

High

454111

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.426

High

575953

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

578238

TAL1
Transaldolase

1

0

High-throughput

0.426

High

597158

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

645740

HSP74
Heat shock protein SSA4

1

0

High-throughput

0.426

High

684533

PDC6
Pyruvate decarboxylase isozyme 3

1

0

High-throughput

0.426

High

743394

TOR2
Serine/threonine-protein kinase TOR2

1

0

High-throughput

0.426

High

816508

SNU13
13 kDa ribonucleoprotein-associated protein

1

0

High-throughput

0.426

High

579509

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.407

High

802087

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.407

High

812976

IMDH1
Putative inosine-5'-monophosphate dehydrogenase 1

1

2

High-throughput

0.407

High

823311

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

2

High-throughput

0.407

High

358238

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

367762

ENO1
Enolase 1

1

0

High-throughput

0.232

Low

368450

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.232

Low

368686

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.232

Low

383136

RLA4
Large ribosomal subunit protein P2B

1

0

High-throughput

0.232

Low

510546

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low

518307

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.232

Low

555093

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.232

Low

572597

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.232

Low

597475

EF3A
Elongation factor 3A

1

0

High-throughput

0.232

Low

598872

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

0

High-throughput

0.232

Low

610157

PDI
Protein disulfide-isomerase

1

0

High-throughput

0.232

Low

631939

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.232

Low

734114

EF2
Elongation factor 2

1

0

High-throughput

0.232

Low

737375

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.232

Low

746035

YME2
Mitochondrial escape protein 2

1

0

High-throughput

0.232

Low

791966

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.232

Low

802946

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

High-throughput

0.232

Low

823312

KPYK2
Pyruvate kinase 2

1

0

High-throughput

0.232

Low

823319

YL001
FAS1 domain-containing protein YLR001C

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025