Protein: DXS
1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS)

Gene: DXS
Organism: Escherichia coli K-12
Interactions: 20
UniProt ID: P77488

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0005829 - cytosol
GO:0006744 - ubiquinone biosynthetic process
GO:0008299 - isoprenoid biosynthetic process
GO:0008615 - pyridoxine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

500831

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.656

High

506313

EFTU1
Elongation factor Tu 1

2

3

High-throughput

0.611

High

498409

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

2

5

High-throughput

0.588

High

501149

RHO
Transcription termination factor Rho

2

3

High-throughput

0.588

High

497395

CSPA
Cold shock protein CspA

1

3

High-throughput

0.536

High

366002

BGAL
Beta-galactosidase

1

0

High-throughput

0.513

High

486842

GLTB
Glutamate synthase [NADPH] large chain

1

0

High-throughput

0.513

High

496937

LON
Lon protease

1

1

High-throughput

0.484

High

497184

ADHE
Bifunctional aldehyde-alcohol dehydrogenase AdhE

1

1

High-throughput

0.484

High

494756

METK
S-adenosylmethionine synthase

1

0

High-throughput

0.458

High

506356

EFTU2
Elongation factor Tu 2

1

3

High-throughput

0.457

High

497371

MREB
Cell shape-determining protein MreB

1

7

High-throughput

0.442

High

1003951

YQEI
Uncharacterized protein YqeI

2

0

High-throughput

0.318

High

492306

RECA
Protein RecA

2

0

High-throughput

0.307

High

497801

PSTB
Phosphate import ATP-binding protein PstB

2

0

High-throughput

0.307

High

421086

APPY
HTH-type transcriptional regulator AppY

1

0

High-throughput

0.279

Low

494878

TATE
Sec-independent protein translocase protein TatE

1

0

High-throughput

0.279

Low

664142

FDNG
Formate dehydrogenase, nitrate-inducible, major subunit

1

0

High-throughput

0.279

Low

811788

YJGL
Uncharacterized protein YjgL

1

0

High-throughput

0.279

Low

495736

CLPS
ATP-dependent Clp protease adapter protein ClpS

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025