Protein: ODP1
Pyruvate dehydrogenase E1 component (PDH E1 component) (EC 1.2.4.1)

Gene: ODP1, aceE
Organism: Escherichia coli K-12
Interactions: 106
UniProt ID: P0AFG8

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004739 - pyruvate dehydrogenase (acetyl-transferring) activity
GO:0005829 - cytosol
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

500779

ODP1
Pyruvate dehydrogenase E1 component

2

0

Small-scale

0.716

High

500831

DXS
1-deoxy-D-xylulose-5-phosphate synthase

1

0

High-throughput

0.656

High

500796

FDNG
Formate dehydrogenase, nitrate-inducible, major subunit

2

1

High-throughput

0.628

High

489624

CH60
Chaperonin GroEL

2

0

High-throughput

0.595

High

449848

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

2

0

High-throughput

0.585

High

497014

DLDH
Dihydrolipoyl dehydrogenase

2

0

High-throughput

0.585

High

500833

YAJL
Protein/nucleic acid deglycase 3

2

0

Small-scale

0.547

High

395157

UVRD
DNA helicase II

1

1

High-throughput

0.536

High

469923

RECB
RecBCD enzyme subunit RecB

1

1

High-throughput

0.536

High

495680

EPMA
Elongation factor P--(R)-beta-lysine ligase

1

1

High-throughput

0.536

High

497620

RLUC
Ribosomal large subunit pseudouridine synthase C

1

1

High-throughput

0.536

High

500806

NAPA
Periplasmic nitrate reductase

1

1

High-throughput

0.536

High

500808

CSPB
Cold shock-like protein CspB

1

1

High-throughput

0.536

High

500811

RLUB
Ribosomal large subunit pseudouridine synthase B

1

1

High-throughput

0.536

High

437530

TSAD
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.513

High

450073

PROA
Gamma-glutamyl phosphate reductase

1

0

High-throughput

0.513

High

466614

ILVB
Acetolactate synthase isozyme 1 large subunit

1

0

High-throughput

0.513

High

467679

ARAA
L-arabinose isomerase

1

0

High-throughput

0.513

High

473282

DNAJ
Chaperone protein DnaJ

1

0

High-throughput

0.513

High

478372

EX3
Exodeoxyribonuclease III

1

0

High-throughput

0.513

High

494719

RUVB
Holliday junction branch migration complex subunit RuvB

1

0

High-throughput

0.513

High

494945

TIG
Trigger factor

1

0

High-throughput

0.513

High

498169

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.513

High

498946

DNAB
Replicative DNA helicase DnaB

1

0

High-throughput

0.513

High

500066

CHEY
Chemotaxis protein CheY

1

0

High-throughput

0.513

High

500676

NUDB
Dihydroneopterin triphosphate diphosphatase

1

0

High-throughput

0.513

High

500783

SUBI
Sulfate-binding protein

1

0

High-throughput

0.513

High

500784

THIO2
Thioredoxin 2

1

0

High-throughput

0.513

High

500785

DPO3A
DNA polymerase III subunit alpha

1

0

High-throughput

0.513

High

500786

SYR
Arginine--tRNA ligase

1

0

High-throughput

0.513

High

500788

TOP3
DNA topoisomerase 3

1

0

High-throughput

0.513

High

500789

FUMB
Fumarate hydratase class I, anaerobic

1

0

High-throughput

0.513

High

500791

DNLJ
DNA ligase

1

0

High-throughput

0.513

High

500793

SYP
Proline--tRNA ligase

1

0

High-throughput

0.513

High

500795

TRMA
tRNA/tmRNA

1

0

High-throughput

0.513

High

500797

LPXM
Lipid A biosynthesis myristoyltransferase

1

0

High-throughput

0.513

High

500798

MNME
tRNA modification GTPase MnmE

1

0

High-throughput

0.513

High

500799

UBIC
Chorismate pyruvate-lyase

1

0

High-throughput

0.513

High

500802

FDHD
Sulfur carrier protein FdhD

1

0

High-throughput

0.513

High

500804

NIKD
Nickel import ATP-binding protein NikD

1

0

High-throughput

0.513

High

500807

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.513

High

500809

NUDK
GDP-mannose pyrophosphatase

1

0

High-throughput

0.513

High

500810

RLMJ
Ribosomal RNA large subunit methyltransferase J

1

0

High-throughput

0.513

High

500813

CAS3
CRISPR-associated endonuclease/helicase Cas3

1

0

High-throughput

0.513

High

500814

RSGA
Small ribosomal subunit biogenesis GTPase RsgA

1

0

High-throughput

0.513

High

500819

FTSK
DNA translocase FtsK

1

0

High-throughput

0.513

High

500830

PTFX1
Multiphosphoryl transfer protein 1

1

0

High-throughput

0.513

High

500792

RECQ
ATP-dependent DNA helicase RecQ

1

1

High-throughput

0.489

High

495482

RHLB
ATP-dependent RNA helicase RhlB

1

1

High-throughput

0.484

High

495659

SYK2
Lysine--tRNA ligase, heat inducible

1

1

High-throughput

0.484

High

496258

CSPD
Cold shock-like protein CspD

1

1

High-throughput

0.484

High

489305

ACP
Acyl carrier protein

1

0

High-throughput

0.464

High

490256

CLPP
ATP-dependent Clp protease proteolytic subunit

1

0

High-throughput

0.464

High

490776

RSMG
Ribosomal RNA small subunit methyltransferase G

1

0

High-throughput

0.464

High

490815

GREA
Transcription elongation factor GreA

1

0

High-throughput

0.464

High

494545

RNH
Ribonuclease HI

1

0

High-throughput

0.464

High

494618

RPOA
DNA-directed RNA polymerase subunit alpha

1

0

High-throughput

0.464

High

494886

TGT
Queuine tRNA-ribosyltransferase

1

0

High-throughput

0.464

High

495133

TUSA
Sulfur carrier protein TusA

1

0

High-throughput

0.464

High

495193

PSRP
Phosphoenolpyruvate synthase regulatory protein

1

0

High-throughput

0.464

High

496722

PHOL
PhoH-like protein

1

0

High-throughput

0.464

High

497092

DEAD
ATP-dependent RNA helicase DeaD

1

0

High-throughput

0.464

High

497306

ZNUC
Zinc import ATP-binding protein ZnuC

1

0

High-throughput

0.464

High

498337

FTSA
Cell division protein FtsA

1

0

High-throughput

0.464

High

499150

HNS
DNA-binding protein H-NS

1

0

High-throughput

0.464

High

500701

NUSA
Transcription termination/antitermination protein NusA

1

0

High-throughput

0.464

High

367444

TRPE
Anthranilate synthase component 1

1

0

High-throughput

0.279

Low

420204

RECD
RecBCD enzyme subunit RecD

1

0

High-throughput

0.279

Low

423988

3MG1
DNA-3-methyladenine glycosylase 1

1

0

High-throughput

0.279

Low

495358

UVRC
UvrABC system protein C

1

0

High-throughput

0.279

Low

495510

YCIU
Putative double-stranded DNA mimic protein YciU

1

0

High-throughput

0.279

Low

497246

YBHF
Probable multidrug ABC transporter ATP-binding protein YbhF

1

0

High-throughput

0.279

Low

498166

END3
Endonuclease III

1

0

High-throughput

0.279

Low

499336

PDHR
Pyruvate dehydrogenase complex repressor

1

0

High-throughput

0.279

Low

500504

HYCI
Hydrogenase 3 maturation protease

1

0

High-throughput

0.279

Low

500781

RELA
GTP pyrophosphokinase

1

0

High-throughput

0.279

Low

500782

RIBF
Bifunctional riboflavin kinase/FMN adenylyltransferase

1

0

High-throughput

0.279

Low

500787

SELB
Selenocysteine-specific elongation factor

1

0

High-throughput

0.279

Low

500790

RECE
Exodeoxyribonuclease 8

1

0

High-throughput

0.279

Low

500794

RECJ
Single-stranded-DNA-specific exonuclease RecJ

1

0

High-throughput

0.279

Low

500800

HOLB
DNA polymerase III subunit delta'

1

0

High-throughput

0.279

Low

500801

3PASE
Inorganic triphosphatase

1

0

High-throughput

0.279

Low

500803

DUSC
tRNA-dihydrouridine(16) synthase

1

0

High-throughput

0.279

Low

500812

PUUB
Gamma-glutamylputrescine oxidoreductase

1

0

High-throughput

0.279

Low

500815

HRPA
ATP-dependent RNA helicase HrpA

1

0

High-throughput

0.279

Low

500816

YRAN
UPF0102 protein YraN

1

0

High-throughput

0.279

Low

500817

UBIU
Ubiquinone biosynthesis protein UbiU

1

0

High-throughput

0.279

Low

500818

AMO
Primary amine oxidase

1

0

High-throughput

0.279

Low

500820

ABPB
Anti-bacteriophage protein B

1

0

High-throughput

0.279

Low

500822

GNGF
Putative gluconeogenesis factor

1

0

High-throughput

0.279

Low

500823

BLUF
Blue light- and temperature-regulated antirepressor BluF

1

0

High-throughput

0.279

Low

500824

YCJY
Uncharacterized protein YcjY

1

0

High-throughput

0.279

Low

500825

STFR
Prophage side tail fiber protein homolog StfR

1

0

High-throughput

0.279

Low

500826

YNFB
UPF0482 protein YnfB

1

0

High-throughput

0.279

Low

500827

YOAA
ATP-dependent DNA helicase YoaA

1

0

High-throughput

0.279

Low

500828

CMOB
tRNA U34 carboxymethyltransferase

1

0

High-throughput

0.279

Low

500829

DGCM
Diguanylate cyclase DgcM

1

0

High-throughput

0.279

Low

500832

YDHW
Uncharacterized protein YdhW

1

0

High-throughput

0.279

Low

495436

TRMB
tRNA

1

0

High-throughput

0.253

Low

496628

LDCI
Inducible lysine decarboxylase

1

0

High-throughput

0.253

Low

500056

CEDA
Cell division activator CedA

1

0

High-throughput

0.253

Low

500186

DMA
DNA adenine methylase

1

0

High-throughput

0.253

Low

500780

OGT
Methylated-DNA--protein-cysteine methyltransferase

1

0

High-throughput

0.253

Low

500821

LOLA
Outer-membrane lipoprotein carrier protein

1

0

High-throughput

0.253

Low

500805

YDBA
Exported protein YdbA

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025