Protein: AP2A
AP-2 complex subunit alpha (Alpha-adaptin) (Clathrin assembly protein complex 2 alpha large chain) (Clathrin assembly protein large alpha chain)

Gene: AP2A, APL3
Organism: Saccharomyces cerevisiae S288C
Interactions: 62
UniProt ID: P38065

Gene Ontology (top 5):
GO:0005935 - cellular bud neck
GO:0006886 - intracellular protein transport
GO:0030122 - AP-2 adaptor complex
GO:0035615 - clathrin adaptor activity
GO:0072583 - clathrin-dependent endocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743417

AP2M
AP-2 complex subunit mu

5

20

High-throughput

0.916

High

743403

AP2S
AP-2 complex subunit sigma

4

20

High-throughput

0.891

High

647443

AP2B
AP-2 complex subunit beta

4

16

Small-scale

0.881

High

743389

AP2A
AP-2 complex subunit alpha

1

15

High-throughput

0.618

High

743400

COPA
Coatomer subunit alpha

1

6

High-throughput

0.618

High

490957

HSP71
Heat shock protein SSA1

3

11

High-throughput

0.578

High

697909

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

7

High-throughput

0.541

High

623463

KPC1
Protein kinase C-like 1

1

3

High-throughput

0.536

High

743393

SSB2
Ribosome-associated molecular chaperone SSB2

2

11

High-throughput

0.504

High

675978

XPO1
Exportin-1

1

15

High-throughput

0.489

High

629959

BPH1
Beige protein homolog 1

1

12

High-throughput

0.479

High

710371

EDE1
EH domain-containing and endocytosis protein 1

1

20

Small-scale

0.479

High

743405

SIZ1
E3 SUMO-protein ligase SIZ1

1

3

High-throughput

0.479

High

743411

VAM6
Vacuolar morphogenesis protein 6

1

7

High-throughput

0.479

High

743416

ENT1
Epsin-1

1

20

Small-scale

0.479

High

743396

ALY2
Arrestin-related trafficking adapter 3

1

6

High-throughput

0.470

High

743395

IRC6
Increased recombination centers protein 6

1

1

High-throughput

0.464

High

602661

MCK1
Protein kinase MCK1

1

5

High-throughput

0.457

High

678174

ZIP1
Synaptonemal complex protein ZIP1

1

2

High-throughput

0.439

High

705984

NIP80
Protein NIP100

1

16

High-throughput

0.439

High

710751

CASP
Protein CASP

1

10

High-throughput

0.439

High

661986

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

664781

BMH1
Protein BMH1

1

3

High-throughput

0.437

High

743390

NU170
Nucleoporin NUP170

1

3

High-throughput

0.437

High

743394

ULP2
Ubiquitin-like-specific protease 2

1

3

High-throughput

0.437

High

743402

H3
Histone H3

1

2

High-throughput

0.437

High

743404

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

743408

RSE1
Pre-mRNA-splicing factor RSE1

1

1

High-throughput

0.437

High

743412

RIO1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.437

High

743415

CMR1
DNA damage-binding protein CMR1

1

3

High-throughput

0.437

High

358021

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.407

High

367972

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.407

High

399426

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.407

High

405173

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.407

High

406987

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.407

High

493738

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.407

High

498889

RL4A
Large ribosomal subunit protein uL4A

1

4

High-throughput

0.407

High

511000

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.407

High

534742

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.407

High

555985

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.407

High

633150

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.407

High

645008

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.407

High

667158

RL8B
Large ribosomal subunit protein eL8B

1

3

High-throughput

0.407

High

694527

HSP7F
Heat shock protein homolog SSE1

1

15

High-throughput

0.407

High

695946

HSP79
Heat shock protein homolog SSE2

1

15

High-throughput

0.407

High

706223

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.407

High

743392

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.407

High

743398

RL4B
Large ribosomal subunit protein uL4B

1

4

High-throughput

0.407

High

743413

RL7B
Large ribosomal subunit protein uL30B

1

2

High-throughput

0.407

High

743414

HSP42
Heat shock protein 42

1

1

High-throughput

0.407

High

539974

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.269

Low

743401

IST1
Vacuolar protein sorting-associated protein IST1

1

0

High-throughput

0.269

Low

541543

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.265

Low

743399

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.265

Low

702655

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

743409

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.251

Low

743410

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.251

Low

743391

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

743406

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

743397

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low

743407

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024