Protein: DOK4
Docking protein 4 (Downstream of tyrosine kinase 4) (Insulin receptor substrate 5) (IRS-5) (IRS5)

Gene: DOK4
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q8TEW6

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0007265 - Ras protein signal transduction
GO:0007399 - nervous system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1184730

DOK3
Docking protein 3

2

11

High-throughput

0.819

High

549911

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

3

0

High-throughput

0.816

High

983640

FAK1
Focal adhesion kinase 1

2

20

High-throughput

0.767

High

1256938

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

3

0

High-throughput

0.720

High

1256954

STK24
Serine/threonine-protein kinase 24

1

2

High-throughput

0.691

High

216557

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

3

1

High-throughput

0.667

High

801522

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

3

1

High-throughput

0.667

High

1201283

KBTB6
Kelch repeat and BTB domain-containing protein 6

3

5

High-throughput

0.667

High

1256931

KBTB7
Kelch repeat and BTB domain-containing protein 7

3

4

High-throughput

0.667

High

1256932

KPBB
Phosphorylase b kinase regulatory subunit beta

3

1

High-throughput

0.667

High

1256936

SAHH3
Adenosylhomocysteinase 3

3

1

High-throughput

0.667

High

1256950

RCOR3
REST corepressor 3

3

3

High-throughput

0.667

High

338739

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

383894

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

1183476

RHOU
Rho-related GTP-binding protein RhoU

1

19

High-throughput

0.647

High

1021436

ANK3
Ankyrin-3

3

0

High-throughput

0.638

High

1256948

CWC22
Pre-mRNA-splicing factor CWC22 homolog

3

0

High-throughput

0.638

High

434248

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

Small-scale

0.618

High

1229944

MIER1
Mesoderm induction early response protein 1

2

3

High-throughput

0.611

High

1256949

HM20A
High mobility group protein 20A

3

3

High-throughput

0.609

High

1256951

RCOR1
REST corepressor 1

3

3

High-throughput

0.609

High

1256945

CCM2
Cerebral cavernous malformations 2 protein

2

0

High-throughput

0.607

High

1012284

INCA1
Protein INCA1

2

1

High-throughput

0.606

High

1256942

PFD5
Prefoldin subunit 5

2

1

High-throughput

0.606

High

855309

STAT2
Signal transducer and activator of transcription 2

2

2

High-throughput

0.594

High

1050724

FHL2
Four and a half LIM domains protein 2

2

1

High-throughput

0.574

High

657845

ELK4
ETS domain-containing protein Elk-4

1

2

Small-scale

0.561

High

232371

KDM1A
Lysine-specific histone demethylase 1A

2

2

High-throughput

0.558

High

1233089

LIX1
Protein limb expression 1 homolog

2

0

High-throughput

0.551

High

1256941

RET7
Retinoid-binding protein 7

2

0

High-throughput

0.551

High

1256952

MARE3
Microtubule-associated protein RP/EB family member 3

2

0

High-throughput

0.551

High

983194

UBE3A
Ubiquitin-protein ligase E3A

1

3

High-throughput

0.536

High

1232117

RHG18
Rho GTPase-activating protein 18

1

4

High-throughput

0.536

High

1256953

KLH20
Kelch-like protein 20

1

2

High-throughput

0.536

High

723077

OPRM
Mu-type opioid receptor

1

3

Small-scale

0.535

High

1251351

OLIG1
Oligodendrocyte transcription factor 1

2

1

High-throughput

0.526

High

49036

SHOT1
Shootin-1

1

0

High-throughput

0.513

High

175536

RPC7
DNA-directed RNA polymerase III subunit RPC7

1

0

High-throughput

0.513

High

314666

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.513

High

447975

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

1036447

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

0

High-throughput

0.513

High

1256934

APC16
Anaphase-promoting complex subunit 16

1

0

High-throughput

0.513

High

1256939

CCD43
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.513

High

1256933

DDT4L
DNA damage-inducible transcript 4-like protein

1

0

High-throughput

0.493

High

1032525

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.489

High

1256930

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

1

1

High-throughput

0.489

High

1256935

KBP
KIF-binding protein

1

1

High-throughput

0.489

High

781043

OPRK
Kappa-type opioid receptor

1

3

Small-scale

0.479

High

324522

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

584265

ELK1
ETS domain-containing protein Elk-1

1

2

Small-scale

0.437

High

781026

OPRD
Delta-type opioid receptor

1

3

Small-scale

0.437

High

241228

PRA10
PRAME family member 10

1

0

High-throughput

0.426

High

124024

SPT5H
Transcription elongation factor SPT5

3

0

High-throughput

0.347

High

1057837

GSE1
Genetic suppressor element 1

3

0

High-throughput

0.347

High

1256947

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

3

0

High-throughput

0.347

High

988787

PAX8
Paired box protein Pax-8

2

0

High-throughput

0.316

High

269256

WBP4
WW domain-binding protein 4

1

0

High-throughput

0.279

Low

930116

SPT4H
Transcription elongation factor SPT4

1

0

High-throughput

0.279

Low

1256937

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.279

Low

1256940

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.279

Low

1256943

CMS1
Protein CMSS1

1

0

High-throughput

0.279

Low

1256944

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

0

High-throughput

0.279

Low

1256946

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024