Protein: FBX8
F-box only protein 8 (F-box/SEC7 protein FBS)

Gene: FBX8, FBXO8
Organism: Homo sapiens
Interactions: 14
UniProt ID: Q9NRD0

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0032012 - regulation of ARF protein signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992347

SKP1
S-phase kinase-associated protein 1

2

0

Small-scale

0.642

High

373246

MYC
Myc proto-oncogene protein

2

1

Small-scale

0.590

High

975269

ARF6
ADP-ribosylation factor 6

1

12

Small-scale

0.579

High

1112730

CUL1
Cullin-1

1

4

Small-scale

0.553

High

549243

CDK4
Cyclin-dependent kinase 4

1

2

Small-scale

0.512

High

839381

MTOR
Serine/threonine-protein kinase mTOR

1

1

Small-scale

0.512

High

1161410

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

Small-scale

0.512

High

1447624

BIN3
Bridging integrator 3

1

2

High-throughput

0.489

High

1151087

PCH2
Pachytene checkpoint protein 2 homolog

1

6

High-throughput

0.439

High

1025597

CDK16
Cyclin-dependent kinase 16

1

1

Small-scale

0.417

High

1447949

SHLB2
Endophilin-B2

1

4

High-throughput

0.417

High

479877

GSTP1
Glutathione S-transferase P

1

0

Small-scale

0.301

High

1092251

NFX1
Transcriptional repressor NF-X1

1

0

Small-scale

0.249

Low

1448273

GGT7
Glutathione hydrolase 7

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025