Protein: PKHG3
Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3)

Gene: PKHG3, PLEKHG3
Organism: Homo sapiens
Interactions: 99
UniProt ID: A1L390

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0030334 - regulation of cell migration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

50620

ANLN
Anillin

3

4

High-throughput

0.847

High

50572

CDC42
Cell division control protein 42 homolog

2

20

High-throughput

0.768

High

50579

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

50610

AURKB
Aurora kinase B

2

6

High-throughput

0.737

High

50588

SRC8
Src substrate cortactin

1

14

High-throughput

0.691

High

50603

KC1AL
Casein kinase I isoform alpha-like

1

6

High-throughput

0.691

High

50574

1433G
14-3-3 protein gamma

3

20

High-throughput

0.650

High

50584

1433F
14-3-3 protein eta

3

20

High-throughput

0.650

High

50631

AKT3
RAC-gamma serine/threonine-protein kinase

1

8

High-throughput

0.618

High

50535

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

50546

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

50554

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

50571

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

50573

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

50580

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

50582

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

50590

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.618

High

50597

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.618

High

50618

ECT2
Protein ECT2

1

18

High-throughput

0.618

High

50567

CAZA2
F-actin-capping protein subunit alpha-2

2

3

High-throughput

0.611

High

50562

LSP1
Lymphocyte-specific protein 1

2

0

High-throughput

0.602

High

50598

PKHA7
Pleckstrin homology domain-containing family A member 7

1

12

High-throughput

0.575

High

50543

ESR1
Estrogen receptor

2

19

High-throughput

0.571

High

50560

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.571

High

50577

RS29
Small ribosomal subunit protein uS14

2

4

High-throughput

0.571

High

50596

SYDE2
Rho GTPase-activating protein SYDE2

2

10

High-throughput

0.571

High

50622

TMOD2
Tropomodulin-2

2

12

High-throughput

0.571

High

50630

CHM2B
Charged multivesicular body protein 2b

2

2

High-throughput

0.571

High

50555

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.553

High

50617

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.553

High

50624

ZMYM2
Zinc finger MYM-type protein 2

2

0

High-throughput

0.547

High

50534

MYO1C
Unconventional myosin-Ic

1

14

High-throughput

0.536

High

50544

S100B
Protein S100-B

1

7

High-throughput

0.536

High

50556

FLNA
Filamin-A

1

14

High-throughput

0.536

High

50564

MYH9
Myosin-9

1

7

High-throughput

0.536

High

50566

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

7

High-throughput

0.536

High

50575

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

8

High-throughput

0.536

High

50578

ACTA
Actin, aortic smooth muscle

1

6

High-throughput

0.536

High

50585

AHNK
Neuroblast differentiation-associated protein AHNAK

1

5

High-throughput

0.536

High

50593

DREB
Drebrin

1

3

High-throughput

0.536

High

50611

MYO19
Unconventional myosin-XIX

1

10

High-throughput

0.536

High

50625

LIMA1
LIM domain and actin-binding protein 1

1

13

High-throughput

0.536

High

50626

KLH21
Kelch-like protein 21

1

4

High-throughput

0.536

High

50627

NXT1
NTF2-related export protein 1

1

2

High-throughput

0.536

High

50541

MYC
Myc proto-oncogene protein

2

11

High-throughput

0.533

High

50537

KDM1A
Lysine-specific histone demethylase 1A

2

1

High-throughput

0.521

High

50599

POTEE
POTE ankyrin domain family member E

2

15

High-throughput

0.521

High

50540

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.513

High

50602

ABRA
Actin-binding Rho-activating protein

1

0

High-throughput

0.513

High

50619

PNRC2
Proline-rich nuclear receptor coactivator 2

1

0

High-throughput

0.513

High

50621

MTMRA
Myotubularin-related protein 10

1

0

High-throughput

0.513

High

50628

PLAT4
Phospholipase A and acyltransferase 4

1

0

High-throughput

0.513

High

50539

MYO1D
Unconventional myosin-Id

1

15

High-throughput

0.489

High

50548

POTEI
POTE ankyrin domain family member I

1

15

High-throughput

0.489

High

50557

S100P
Protein S100-P

1

7

High-throughput

0.489

High

50559

S10A2
Protein S100-A2

1

7

High-throughput

0.489

High

50594

ACTBL
Beta-actin-like protein 2

1

14

High-throughput

0.489

High

50607

MY18A
Unconventional myosin-XVIIIa

1

13

High-throughput

0.489

High

50542

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

12

High-throughput

0.479

High

50545

GELS
Gelsolin

1

6

High-throughput

0.479

High

50552

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

50558

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

50561

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

50568

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

50570

ACTB
Actin, cytoplasmic 1

1

15

High-throughput

0.479

High

50576

1433E
14-3-3 protein epsilon

1

6

High-throughput

0.479

High

50581

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

50589

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

50591

HMGN3
High mobility group nucleosome-binding domain-containing protein 3

1

1

High-throughput

0.479

High

50615

CCDC8
Coiled-coil domain-containing protein 8

1

5

High-throughput

0.479

High

50623

ANFY1
Rabankyrin-5

1

7

High-throughput

0.479

High

50595

SPIN3
Spindlin-3

1

0

High-throughput

0.458

High

50604

MTMRE
Myotubularin-related protein 14

1

0

High-throughput

0.458

High

50616

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

50553

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.445

High

50565

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

4

High-throughput

0.445

High

50592

NF2L2
Nuclear factor erythroid 2-related factor 2

1

1

High-throughput

0.445

High

50547

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

12

High-throughput

0.437

High

50569

FOXA1
Hepatocyte nuclear factor 3-alpha

1

3

High-throughput

0.437

High

50583

LMNB2
Lamin-B2

1

11

High-throughput

0.437

High

50586

CIRBP
Cold-inducible RNA-binding protein

1

11

High-throughput

0.437

High

50605

TM263
Transmembrane protein 263

1

4

High-throughput

0.437

High

50608

ESR2
Estrogen receptor beta

1

19

High-throughput

0.437

High

50632

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

1

High-throughput

0.437

High

50549

ST3L3
STAG3-like protein 3

1

1

High-throughput

0.407

High

50551

CALM3
Calmodulin-3

1

1

High-throughput

0.407

High

50550

SAA1
Serum amyloid A-1 protein

1

0

High-throughput

0.279

Low

50563

IL13
Interleukin-13

1

0

High-throughput

0.279

Low

50587

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.279

Low

50601

MGDP1
Magnesium-dependent phosphatase 1

1

0

High-throughput

0.279

Low

50606

JPH3
Junctophilin-3

1

0

High-throughput

0.279

Low

50609

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.279

Low

50612

CGRE1
Cell growth regulator with EF hand domain protein 1

1

0

High-throughput

0.279

Low

50613

S39A3
Zinc transporter ZIP3

1

0

High-throughput

0.279

Low

50614

TM147
BOS complex subunit TMEM147

1

0

High-throughput

0.279

Low

50629

MUCEN
Endomucin

1

0

High-throughput

0.279

Low

50536

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.249

Low

50538

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.249

Low

50600

DET1
DET1 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024