Protein: SPEA
Biosynthetic arginine decarboxylase (ADC) (EC 4.1.1.19)

Gene: SPEA
Organism: Escherichia coli K-12
Interactions: 20
UniProt ID: P21170

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0006527 - L-arginine catabolic process
GO:0008295 - spermidine biosynthetic process
GO:0008792 - arginine decarboxylase activity
GO:0009446 - putrescine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636363

SPEA
Biosynthetic arginine decarboxylase

1

6

High-throughput

0.698

High

495836

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.513

High

616840

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

490485

HSCB
Co-chaperone protein HscB

1

0

High-throughput

0.282

High

497881

HYDN
Electron transport protein HydN

1

0

High-throughput

0.282

High

636366

YDFU
Uncharacterized protein YdfU

1

0

High-throughput

0.282

High

382708

RS7
Small ribosomal subunit protein uS7

1

0

High-throughput

0.279

Low

480636

RHAS
HTH-type transcriptional activator RhaS

1

0

High-throughput

0.279

Low

493777

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.279

Low

493931

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.279

Low

494118

RS4
Small ribosomal subunit protein uS4

1

0

High-throughput

0.279

Low

495685

LFTR
Leucyl/phenylalanyl-tRNA--protein transferase

1

0

High-throughput

0.279

Low

497947

IPRA
Inhibitor of hydrogen peroxide resistance

1

0

High-throughput

0.279

Low

501168

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.279

Low

636364

PRIC
Replication restart protein PriC

1

0

High-throughput

0.279

Low

636365

RL2
Large ribosomal subunit protein uL2

1

0

High-throughput

0.279

Low

636367

YDEP
Protein YdeP

1

0

High-throughput

0.279

Low

493118

RL34
Large ribosomal subunit protein bL34

1

0

Small-scale

0.249

Low

498915

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025