Protein: LON
Lon protease (EC 3.4.21.53) (ATP-dependent protease La)

Gene: LON
Organism: Escherichia coli K-12
Interactions: 81
UniProt ID: P0A9M0

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0004176 - ATP-dependent peptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

464953

EFTU1
Elongation factor Tu 1

2

2

High-throughput

0.759

High

416840

DPO3X
DNA polymerase III subunit tau

1

5

High-throughput

0.691

High

464935

LON
Lon protease

1

15

Small-scale

0.647

High

458381

HSLU
ATP-dependent protease ATPase subunit HslU

1

2

High-throughput

0.625

High

464940

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

1

8

High-throughput

0.618

High

461919

RS3
Small ribosomal subunit protein uS3

2

2

High-throughput

0.588

High

464936

RL13
Large ribosomal subunit protein uL13

2

1

High-throughput

0.588

High

464952

RLME
Ribosomal RNA large subunit methyltransferase E

2

1

High-throughput

0.588

High

460174

HSLV
ATP-dependent protease subunit HslV

1

0

High-throughput

0.586

High

464949

SECB
Protein-export protein SecB

2

0

High-throughput

0.585

High

464951

SSB
Single-stranded DNA-binding protein

2

2

High-throughput

0.571

High

457426

END4
Endonuclease 4

2

0

High-throughput

0.563

High

458918

HFQ
RNA-binding protein Hfq

2

0

High-throughput

0.563

High

461187

RL9
Large ribosomal subunit protein bL9

2

0

High-throughput

0.563

High

464947

RL21
Large ribosomal subunit protein bL21

2

0

High-throughput

0.563

High

464950

SRP54
Signal recognition particle protein

2

0

High-throughput

0.563

High

464963

CBPA
Curved DNA-binding protein

1

2

High-throughput

0.536

High

464965

ZNTA
Zinc/cadmium/lead-transporting P-type ATPase

1

2

High-throughput

0.536

High

464984

SUFS
Cysteine desulfurase

1

1

High-throughput

0.536

High

368566

DNAA
Chromosomal replication initiator protein DnaA

1

0

High-throughput

0.513

High

449035

GRPE
Protein GrpE

1

0

High-throughput

0.513

High

463757

CLPS
ATP-dependent Clp protease adapter protein ClpS

1

0

High-throughput

0.513

High

463847

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.513

High

464937

SAPF
Putrescine export system ATP-binding protein SapF

1

0

High-throughput

0.513

High

464944

ENTB
Enterobactin synthase component B

1

0

High-throughput

0.513

High

464946

SSPB
Stringent starvation protein B

1

0

High-throughput

0.513

High

464954

YBHB
UPF0098 protein YbhB

1

0

High-throughput

0.513

High

464955

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.513

High

464956

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

464958

WAAY
Lipopolysaccharide core heptose(II) kinase WaaY

1

0

High-throughput

0.513

High

464960

MOAD
Molybdopterin synthase sulfur carrier subunit

1

0

High-throughput

0.513

High

464977

YBJD
Uncharacterized protein YbjD

1

0

High-throughput

0.513

High

464979

YCJX
Ras-like GTPase YcjX

1

0

High-throughput

0.513

High

464980

PBPC
Penicillin-binding protein 1C

1

0

High-throughput

0.513

High

464982

CITC
[Citrate [pro-3S]-lyase] ligase

1

0

High-throughput

0.513

High

464983

LSRK
Autoinducer-2 kinase

1

0

High-throughput

0.513

High

464986

YDJF
Uncharacterized HTH-type transcriptional regulator YdjF

1

0

High-throughput

0.513

High

464987

YAJO
1-deoxyxylulose-5-phosphate synthase YajO

1

0

High-throughput

0.513

High

464939

YBDG
Miniconductance mechanosensitive channel YbdG

1

1

High-throughput

0.489

High

464941

CYOA
Cytochrome bo(3) ubiquinol oxidase subunit 2

1

2

High-throughput

0.489

High

464957

NARY
Respiratory nitrate reductase 2 beta chain

1

1

High-throughput

0.489

High

464966

MSCM
Miniconductance mechanosensitive channel MscM

1

3

High-throughput

0.489

High

357040

RS7
Small ribosomal subunit protein uS7

1

1

High-throughput

0.484

High

415808

ERA
GTPase Era

1

4

High-throughput

0.484

High

457576

CH60
Chaperonin GroEL

1

5

High-throughput

0.484

High

458298

CLPP
ATP-dependent Clp protease proteolytic subunit

1

3

High-throughput

0.484

High

459077

DNAK
Chaperone protein DnaK

1

7

High-throughput

0.484

High

460869

RL20
Large ribosomal subunit protein bL20

1

1

High-throughput

0.484

High

461753

RS2
Small ribosomal subunit protein uS2

1

2

High-throughput

0.484

High

462417

RS8
Small ribosomal subunit protein uS8

1

3

High-throughput

0.484

High

464970

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.484

High

464988

FSAA
Fructose-6-phosphate aldolase 1

1

1

High-throughput

0.484

High

458182

CH10
Co-chaperonin GroES

1

1

High-throughput

0.479

High

368603

DPO3E
DNA polymerase III subunit epsilon

1

0

High-throughput

0.464

High

458716

FABZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

1

0

High-throughput

0.464

High

464942

DPS
DNA protection during starvation protein

1

0

High-throughput

0.464

High

464959

HOLC
DNA polymerase III subunit chi

1

0

High-throughput

0.464

High

464964

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.464

High

464971

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.464

High

464974

FLAV
Flavodoxin 1

1

0

High-throughput

0.464

High

464985

DXS
1-deoxy-D-xylulose-5-phosphate synthase

1

0

High-throughput

0.464

High

464989

UACR
Putative uric acid sigma-54-dependent transcriptional regulator UacR

1

0

High-throughput

0.464

High

460746

RL1
Large ribosomal subunit protein uL1

1

0

High-throughput

0.458

High

463603

YEEX
UPF0265 protein YeeX

1

0

High-throughput

0.458

High

464945

GCH1L
GTP cyclohydrolase 1 type 2 homolog

1

0

High-throughput

0.458

High

464967

YJGL
Uncharacterized protein YjgL

3

0

High-throughput

0.335

High

464969

UBIU
Ubiquinone biosynthesis protein UbiU

2

0

High-throughput

0.307

High

464961

TORA
Trimethylamine-N-oxide reductase 1

1

0

Small-scale

0.297

High

464976

PGAD
Biofilm PGA synthesis protein PgaD

1

0

High-throughput

0.282

High

462824

SMG
Protein Smg

1

0

High-throughput

0.279

Low

464938

YLBF
Uncharacterized protein YlbF

1

0

High-throughput

0.279

Low

464943

FLGG
Flagellar basal-body rod protein FlgG

1

0

High-throughput

0.279

Low

464948

SUBI
Sulfate-binding protein

1

0

High-throughput

0.279

Low

464978

BLUF
Blue light- and temperature-regulated antirepressor BluF

1

0

High-throughput

0.279

Low

464981

DJLC
Uncharacterized J domain-containing protein DjlC

1

0

High-throughput

0.279

Low

464975

YODC
Uncharacterized protein YodC

1

0

High-throughput

0.261

Low

464972

LOLA
Outer-membrane lipoprotein carrier protein

1

0

High-throughput

0.253

Low

464968

YJJU
Uncharacterized protein YjjU

1

0

High-throughput

0.249

Low

464973

LOLB
Outer-membrane lipoprotein LolB

1

0

High-throughput

0.249

Low

464962

YDBA
Exported protein YdbA

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024