Protein: TOR1
Serine/threonine-protein kinase TOR1 (EC 2.7.11.1) (Dominant rapamycin resistance protein 1) (Phosphatidylinositol kinase homolog TOR1) (Target of rapamycin kinase 1)

Gene: TOR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 148
UniProt ID: P35169

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000329 - fungal-type vacuole membrane
GO:0001558 - regulation of cell growth
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

762832

LST8
Target of rapamycin complex subunit LST8

7

15

Small-scale

0.965

High

762861

RAGAB
GTP-binding protein GTR1

3

7

Small-scale

0.854

High

628058

FKBP
FK506-binding protein 1

2

8

Small-scale

0.838

High

376288

YPT1
GTP-binding protein YPT1

2

5

Small-scale

0.806

High

762817

KOG1
Target of rapamycin complex 1 subunit KOG1

18

14

Small-scale

0.763

High

762877

TCO89
Target of rapamycin complex 1 subunit TCO89

6

1

Small-scale

0.733

High

548896

SCH9
Serine/threonine-protein kinase SCH9

6

20

Small-scale

0.729

High

743376

TOR2
Serine/threonine-protein kinase TOR2

2

17

Small-scale

0.712

High

615011

GLN3
Nitrogen regulatory protein GLN3

5

6

Small-scale

0.710

High

762850

PIB2
Glutamine sensor PIB2

4

1

Small-scale

0.703

High

762860

2ABA
Protein phosphatase PP2A regulatory subunit B

1

4

High-throughput

0.691

High

762870

TAP42
Type 2A phosphatase-associated protein 42

3

1

Small-scale

0.656

High

762835

RGD2
Rho-GTPase-activating protein RGD2

1

1

High-throughput

0.621

High

762853

RAGCD
GTP-binding protein GTR2

1

7

High-throughput

0.621

High

654777

URE2
Transcriptional regulator URE2

2

1

Small-scale

0.619

High

762811

RTG3
Retrograde regulation protein 3

2

1

High-throughput

0.614

High

762827

SERA
D-3-phosphoglycerate dehydrogenase 1

2

1

Small-scale

0.594

High

479675

F16P
Fructose-1,6-bisphosphatase

2

2

Small-scale

0.584

High

762830

DSN1
Kinetochore-associated protein DSN1

2

3

High-throughput

0.584

High

762874

RTC1
Restriction of telomere capping protein 1

1

11

High-throughput

0.578

High

726917

HS104
Heat shock protein 104

2

6

High-throughput

0.576

High

737398

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

8

High-throughput

0.575

High

762804

TOR1
Serine/threonine-protein kinase TOR1

1

17

High-throughput

0.575

High

762809

SWD3
COMPASS component SWD3

1

10

High-throughput

0.575

High

752093

HSP78
Heat shock protein 78, mitochondrial

2

6

High-throughput

0.571

High

762858

APJ1
J domain-containing protein APJ1

2

8

High-throughput

0.571

High

548195

BIK1
Nuclear fusion protein BIK1

2

3

Small-scale

0.566

High

762808

YPK3
Serine/threonine-protein kinase YPK3

1

20

Small-scale

0.561

High

645359

XRN1
5'-3' exoribonuclease 1

1

2

High-throughput

0.552

High

762865

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.547

High

646122

NPR1
Nitrogen permease reactivator protein

1

11

High-throughput

0.536

High

756601

MKS1
Negative regulator of RAS-cAMP pathway

1

1

High-throughput

0.536

High

762805

NNK1
Nitrogen network kinase 1

1

6

High-throughput

0.536

High

762806

KDX1
Serine/threonine-protein kinase KDX1

1

5

High-throughput

0.536

High

762814

KSP1
Serine/threonine-protein kinase KSP1

1

19

High-throughput

0.536

High

762831

SA185
SIT4-associating protein SAP185

1

5

High-throughput

0.536

High

762848

SAP4
SIT4-associating protein SAP4

1

5

High-throughput

0.536

High

762852

FMP48
Probable serine/threonine-protein kinase FMP48

1

9

High-throughput

0.536

High

762862

CDC14
Tyrosine-protein phosphatase CDC14

1

8

High-throughput

0.536

High

762866

SKY1
Serine/threonine-protein kinase SKY1

1

17

High-throughput

0.536

High

762826

VHR2
Transcription factor VHR2

1

1

Small-scale

0.527

High

762841

TRM61
tRNA

1

1

High-throughput

0.515

High

762882

PKH2
Serine/threonine-protein kinase PKH2

1

19

High-throughput

0.515

High

762844

TAX4
Protein TAX4

1

0

High-throughput

0.513

High

762883

YL108
BTB/POZ domain-containing protein YLR108C

1

0

High-throughput

0.513

High

639525

DAL81
Transcriptional activator protein DAL81

1

1

Small-scale

0.508

High

684906

DAL80
Nitrogen regulatory protein DAL80

1

6

Small-scale

0.508

High

762834

GZF3
Protein GZF3

1

6

Small-scale

0.508

High

762836

GAT1
Transcriptional regulatory protein GAT1

1

6

Small-scale

0.508

High

762880

BBP
Branchpoint-bridging protein

1

1

High-throughput

0.508

High

453927

IF4E
Eukaryotic translation initiation factor 4E

1

2

Small-scale

0.501

High

554682

YPK1
Serine/threonine-protein kinase YPK1

1

20

Small-scale

0.501

High

664271

SSD1
Protein SSD1

1

3

High-throughput

0.501

High

760524

FAB1
1-phosphatidylinositol 3-phosphate 5-kinase FAB1

1

3

Small-scale

0.501

High

760647

WHI3
Protein WHI3

1

2

High-throughput

0.501

High

762829

VPS27
Vacuolar protein sorting-associated protein 27

1

6

Small-scale

0.501

High

762833

MAF1
Repressor of RNA polymerase III transcription MAF1

1

1

Small-scale

0.501

High

762839

SCD6
Protein SCD6

1

2

High-throughput

0.501

High

762871

ATG13
Autophagy-related protein 13

1

1

Small-scale

0.501

High

762879

VPS54
Vacuolar protein sorting-associated protein 54

1

0

High-throughput

0.493

High

639893

DAL82
Protein DAL82

1

0

Small-scale

0.486

High

590597

HSP26
Heat shock protein 26

1

2

High-throughput

0.481

High

607747

HXKG
Glucokinase-1

1

1

High-throughput

0.481

High

677267

MET14
Karyogamy protein KAR4

1

3

High-throughput

0.481

High

721599

RENT1
ATP-dependent helicase NAM7

1

8

High-throughput

0.481

High

738579

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

3

High-throughput

0.481

High

762837

WWM1
WW domain-containing protein WWM1

1

1

High-throughput

0.481

High

762843

LSM1
LSM1-LSM7 complex subunit LSM1

1

2

High-throughput

0.481

High

762846

PSP2
Protein PSP2

1

1

High-throughput

0.481

High

762855

DCP2
m7GpppN-mRNA hydrolase

1

3

High-throughput

0.481

High

762856

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.481

High

762869

ICY1
Interacting with cytoskeleton protein 1

1

1

High-throughput

0.481

High

762886

DCP1
mRNA-decapping enzyme subunit 1

1

1

High-throughput

0.481

High

558669

CAF20
Cap-associated protein CAF20

1

0

Small-scale

0.480

High

758176

LST4
Protein LST4

1

0

Small-scale

0.480

High

382011

H4
Histone H4

1

6

High-throughput

0.479

High

403441

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

Small-scale

0.479

High

579155

HSC82
ATP-dependent molecular chaperone HSC82

1

13

High-throughput

0.479

High

584359

GCN2
eIF-2-alpha kinase GCN2

1

10

Small-scale

0.479

High

644617

MDHC
Malate dehydrogenase, cytoplasmic

1

2

Small-scale

0.479

High

678647

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

3

High-throughput

0.479

High

706719

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

736510

SFP1
Transcription factor SFP1

1

3

Small-scale

0.479

High

760567

TSA1
Peroxiredoxin TSA1

1

1

Small-scale

0.479

High

762807

TTI1
TEL2-interacting protein 1

1

16

High-throughput

0.479

High

762812

NU170
Nucleoporin NUP170

1

3

High-throughput

0.479

High

762813

RCK1
Serine/threonine-protein kinase RCK1

1

18

High-throughput

0.479

High

762820

DHH1
ATP-dependent RNA helicase DHH1

1

6

High-throughput

0.479

High

762823

VAC8
Vacuolar protein 8

1

9

High-throughput

0.479

High

762859

H3
Histone H3

1

10

High-throughput

0.479

High

762868

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

762876

NCBP2
Nuclear cap-binding protein subunit 2

1

3

High-throughput

0.479

High

762884

LAS17
Proline-rich protein LAS17

1

4

Small-scale

0.479

High

762838

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

12

High-throughput

0.470

High

361430

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.460

High

427981

HEM2
Delta-aminolevulinic acid dehydratase

1

0

High-throughput

0.460

High

740250

SMI1
Cell wall assembly regulator SMI1

1

0

High-throughput

0.460

High

762816

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.460

High

762822

SLN1
Osmosensing histidine protein kinase SLN1

1

0

High-throughput

0.460

High

762863

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

0

High-throughput

0.460

High

762867

MIX17
Mitochondrial intermembrane space cysteine motif-containing protein MIX17

1

0

High-throughput

0.460

High

762875

MCA1
Metacaspase-1

1

0

High-throughput

0.460

High

534179

PCKA
Phosphoenolpyruvate carboxykinase

1

0

Small-scale

0.458

High

553911

WHI2
Growth regulation protein

1

0

Small-scale

0.458

High

701481

ACEA
Isocitrate lyase

1

0

Small-scale

0.458

High

762854

PBP1
PAB1-binding protein 1

1

0

Small-scale

0.458

High

762878

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

392521

HSP82
ATP-dependent molecular chaperone HSP82

1

13

High-throughput

0.445

High

481580

HSP73
Heat shock protein SSA3

1

12

High-throughput

0.445

High

523546

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

526343

HSP72
Heat shock protein SSA2

1

12

High-throughput

0.445

High

544385

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

575921

CYPH
Peptidyl-prolyl cis-trans isomerase

1

3

High-throughput

0.445

High

670244

NAP1
Nucleosome assembly protein

1

1

High-throughput

0.445

High

670556

SIS1
Protein SIS1

1

7

High-throughput

0.445

High

675888

MAS5
Mitochondrial protein import protein MAS5

1

8

High-throughput

0.445

High

694519

SPT5
Transcription elongation factor SPT5

1

2

High-throughput

0.445

High

736628

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.445

High

741304

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

762815

SSZ1
Ribosome-associated complex subunit SSZ1

1

6

High-throughput

0.445

High

762818

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.445

High

762819

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.445

High

762824

HSP7E
Heat shock protein SSC3, mitochondrial

1

6

High-throughput

0.445

High

762828

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

762842

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.445

High

762845

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.445

High

762864

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

9

High-throughput

0.445

High

762873

BRE1
E3 ubiquitin-protein ligase BRE1

1

12

High-throughput

0.445

High

762881

RIO1
Serine/threonine-protein kinase RIO1

1

6

High-throughput

0.445

High

762885

RUVB2
RuvB-like protein 2

1

19

High-throughput

0.445

High

484751

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.439

High

668897

ERG6
Sterol 24-C-methyltransferase ERG6

1

3

High-throughput

0.439

High

762872

PEX19
Peroxisomal membrane protein import receptor PEX19

1

1

High-throughput

0.439

High

748324

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

427030

FUR4
Uracil permease

1

0

High-throughput

0.426

High

762810

SEA4
SEH-associated protein 4

1

0

High-throughput

0.426

High

762821

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

762847

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

762857

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

577091

SEC63
Protein translocation protein SEC63

1

1

High-throughput

0.407

High

577370

MTF1
Mitochondrial transcription factor 1

1

0

High-throughput

0.269

Low

736542

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.251

Low

743860

YEF3
Uncharacterized protein YEL043W

1

0

High-throughput

0.251

Low

762849

YGY5
Uncharacterized protein YGL235W

1

0

High-throughput

0.251

Low

762851

IMO32
Probable alcohol acetyltransferase

1

0

High-throughput

0.251

Low

762825

BIM1
Protein BIM1

1

0

Small-scale

0.249

Low

762840

STU2
Protein STU2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025