Protein: RIB4
6,7-dimethyl-8-ribityllumazine synthase (DMRL synthase) (LS) (Lumazine synthase) (EC 2.5.1.78)

Gene: RIB4
Organism: Saccharomyces cerevisiae S288C
Interactions: 23
UniProt ID: P50861

Gene Ontology (top 5):
GO:0000906 - 6,7-dimethyl-8-ribityllumazine synthase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005758 - mitochondrial intermembrane space
GO:0009231 - riboflavin biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

898158

RIB4
6,7-dimethyl-8-ribityllumazine synthase

1

4

High-throughput

0.656

High

460992

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.513

High

574594

YAK1
Dual specificity protein kinase YAK1

1

0

High-throughput

0.513

High

645953

DBF2
Cell cycle protein kinase DBF2

1

0

High-throughput

0.513

High

898160

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

798450

NTM1
Alpha N-terminal protein methyltransferase 1

1

0

High-throughput

0.486

High

898163

MHT1
Homocysteine S-methyltransferase 1

1

0

High-throughput

0.486

High

393026

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

579730

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

510649

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.458

High

707625

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

752499

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

898159

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

898162

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

819245

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

898161

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.426

High

825747

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.269

Low

738672

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.265

Low

506398

YK104
Putative uncharacterized protein YKR104W

1

0

High-throughput

0.251

Low

672693

BPH1
Beige protein homolog 1

1

0

High-throughput

0.249

Low

812480

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

877856

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025