Protein: BPH1
Beige protein homolog 1

Gene: BPH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 153
UniProt ID: P25356

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0005739 - mitochondrion
GO:0005770 - late endosome
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

672624

BPH1
Beige protein homolog 1

1

15

High-throughput

0.618

High

509417

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

9

High-throughput

0.501

High

672642

YPT52
GTP-binding protein YPT52

1

12

High-throughput

0.501

High

448885

TYSY
Thymidylate synthase

1

1

High-throughput

0.479

High

575570

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

5

High-throughput

0.479

High

635022

VPS33
Vacuolar protein sorting-associated protein 33

1

3

High-throughput

0.479

High

652852

TRX2
Thioredoxin-2

1

10

High-throughput

0.479

High

661374

PSA3
Proteasome subunit alpha type-3

1

5

High-throughput

0.479

High

672626

AP2B
AP-2 complex subunit beta

1

8

High-throughput

0.479

High

672627

PEP3
Vacuolar membrane protein PEP3

1

2

High-throughput

0.479

High

672631

MDHP
Malate dehydrogenase, peroxisomal

1

2

High-throughput

0.479

High

672634

HBS1
Elongation factor 1 alpha-like protein

1

3

High-throughput

0.479

High

672635

PEP12
Syntaxin PEP12

1

3

High-throughput

0.479

High

672638

VPS35
Vacuolar protein sorting-associated protein 35

1

1

High-throughput

0.479

High

672639

FAB1
1-phosphatidylinositol 3-phosphate 5-kinase FAB1

1

20

High-throughput

0.479

High

672643

SN114
Pre-mRNA-splicing factor SNU114

1

2

High-throughput

0.479

High

672647

AP2A
AP-2 complex subunit alpha

1

7

High-throughput

0.479

High

672650

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

5

High-throughput

0.479

High

672651

FES1
Hsp70 nucleotide exchange factor FES1

1

2

High-throughput

0.479

High

672661

VPS45
Vacuolar protein sorting-associated protein 45

1

3

High-throughput

0.479

High

672663

CAJ1
Protein CAJ1

1

12

High-throughput

0.479

High

672664

YCFI
Metal resistance protein YCF1

1

2

High-throughput

0.479

High

672667

KC13
Casein kinase I homolog 3

1

13

High-throughput

0.479

High

672680

LSB6
Phosphatidylinositol 4-kinase LSB6

1

1

High-throughput

0.479

High

672684

VTC2
Vacuolar transporter chaperone complex subunit 2

1

2

High-throughput

0.479

High

672685

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

6

High-throughput

0.479

High

672690

GYP7
GTPase-activating protein GYP7

1

2

High-throughput

0.479

High

672691

BRO1
Vacuolar-sorting protein BRO1

1

1

High-throughput

0.479

High

672698

COPZ
Coatomer subunit zeta

1

1

High-throughput

0.479

High

672709

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

2

High-throughput

0.479

High

672714

GYL1
Probable GTPase-activating protein GYL1

1

4

High-throughput

0.479

High

672718

VBA4
Vacuolar basic amino acid transporter 4

1

1

High-throughput

0.479

High

672720

PAL1
Protein PAL1

1

1

High-throughput

0.479

High

672723

TUS1
Rho1 guanine nucleotide exchange factor TUS1

1

7

High-throughput

0.479

High

672725

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

9

High-throughput

0.479

High

672728

YL419
Putative ATP-dependent RNA helicase YLR419W

1

6

High-throughput

0.479

High

672729

VAC14
Vacuole morphology and inheritance protein 14

1

1

High-throughput

0.479

High

672731

ATG20
Autophagy-related protein 20

1

1

High-throughput

0.479

High

672732

VPS13
Intermembrane lipid transfer protein VPS13

1

3

High-throughput

0.479

High

672737

AP3D
AP-3 complex subunit delta

1

7

High-throughput

0.479

High

672742

NYV1
Vacuolar v-SNARE NYV1

1

1

High-throughput

0.479

High

672745

YD199
Putative metabolite transport protein YDL199C

1

1

High-throughput

0.479

High

672741

RPN5
26S proteasome regulatory subunit RPN5

1

5

High-throughput

0.470

High

399300

PYRF
Orotidine 5'-phosphate decarboxylase

1

0

High-throughput

0.458

High

556590

PEP5
E3 ubiquitin-protein ligase PEP5

1

0

High-throughput

0.458

High

668243

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

672629

STX8
Syntaxin-8

1

0

High-throughput

0.458

High

672630

FUN26
Nucleoside transporter FUN26

1

0

High-throughput

0.458

High

672641

KES1
Oxysterol-binding protein homolog 4

1

0

High-throughput

0.458

High

672645

RQT4
RQC trigger complex subunit RQT4

1

0

High-throughput

0.458

High

672649

AP3M
AP-3 complex subunit mu

1

0

High-throughput

0.458

High

672652

FTH1
Iron transporter FTH1

1

0

High-throughput

0.458

High

672653

VHC1
Vacuolar cation-chloride cotransporter 1

1

0

High-throughput

0.458

High

672657

TDA3
Putative oxidoreductase TDA3

1

0

High-throughput

0.458

High

672662

VTC5
Vacuole transporter chaperone complex subunit 5

1

0

High-throughput

0.458

High

672671

YNU8
Uncharacterized protein YNL208W

1

0

High-throughput

0.458

High

672686

FAR7
Factor arrest protein 7

1

0

High-throughput

0.458

High

672687

MHP1
MAP-homologous protein 1

1

0

High-throughput

0.458

High

672688

MTC1
Maintenance of telomere capping protein 1

1

0

High-throughput

0.458

High

672695

YIP5
Protein YIP5

1

0

High-throughput

0.458

High

672696

PIB2
Glutamine sensor PIB2

1

0

High-throughput

0.458

High

672702

VAC7
Vacuolar segregation protein 7

1

0

High-throughput

0.458

High

672703

UBX4
UBX domain-containing protein 4

1

0

High-throughput

0.458

High

672704

VPS9
Vacuolar protein sorting-associated protein 9

1

0

High-throughput

0.458

High

672705

ORN
Oligoribonuclease, mitochondrial

1

0

High-throughput

0.458

High

672708

MEH1
Protein MEH1

1

0

High-throughput

0.458

High

672711

EFR3
Protein EFR3

1

0

High-throughput

0.458

High

672713

NHX1
Endosomal/prevacuolar sodium/hydrogen exchanger

1

0

High-throughput

0.458

High

672715

VTI1
t-SNARE VTI1

1

0

High-throughput

0.458

High

672721

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.458

High

672726

YL413
Cell membrane protein YLR413W

1

0

High-throughput

0.458

High

672730

MRX9
MIOREX complex component 9

1

0

High-throughput

0.458

High

672735

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

672743

MAM3
Protein MAM3

1

0

High-throughput

0.458

High

672747

FRE6
Ferric reductase transmembrane component 6

1

0

High-throughput

0.458

High

672749

ENT1
Epsin-1

1

0

High-throughput

0.458

High

672752

VPS5
Vacuolar protein sorting-associated protein 5

1

0

High-throughput

0.458

High

392288

HSP82
ATP-dependent molecular chaperone HSP82

1

10

High-throughput

0.445

High

523159

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.445

High

526008

HSP72
Heat shock protein SSA2

1

15

High-throughput

0.445

High

543930

SSB1
Ribosome-associated molecular chaperone SSB1

1

13

High-throughput

0.445

High

672625

MAS5
Mitochondrial protein import protein MAS5

1

10

High-throughput

0.445

High

672632

HSP7F
Heat shock protein homolog SSE1

1

16

High-throughput

0.445

High

672670

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

672676

DJP1
DnaJ-like protein 1

1

12

High-throughput

0.445

High

453334

CARA
Carbamoyl phosphate synthase arginine-specific small chain

1

1

High-throughput

0.437

High

484267

KEX1
Pheromone-processing carboxypeptidase KEX1

1

1

High-throughput

0.437

High

577268

NSP1
Nucleoporin NSP1

1

7

High-throughput

0.437

High

642008

DPOE
DNA polymerase epsilon catalytic subunit A

1

1

High-throughput

0.437

High

645879

DBF2
Cell cycle protein kinase DBF2

1

8

High-throughput

0.437

High

646286

SLY41
Uncharacterized transporter SLY41

1

1

High-throughput

0.437

High

654700

SPA2
Protein SPA2

1

4

High-throughput

0.437

High

665780

KPC1
Protein kinase C-like 1

1

3

High-throughput

0.437

High

672640

PP2C1
Protein phosphatase 2C homolog 1

1

1

High-throughput

0.437

High

672648

PP2C4
Protein phosphatase 2C homolog 4

1

3

High-throughput

0.437

High

672654

KDSR
3-ketodihydrosphingosine reductase TSC10

1

3

High-throughput

0.437

High

672658

YHP7
Uncharacterized protein YHR097C

1

1

High-throughput

0.437

High

672660

SPC97
Spindle pole body component SPC97

1

11

High-throughput

0.437

High

672673

VPS27
Vacuolar protein sorting-associated protein 27

1

4

High-throughput

0.437

High

672675

AIM21
Altered inheritance of mitochondria protein 21

1

3

High-throughput

0.437

High

672677

AXL1
Putative protease AXL1

1

4

High-throughput

0.437

High

672681

GCN20
Protein GCN20

1

1

High-throughput

0.437

High

672682

OTU1
Ubiquitin thioesterase OTU1

1

1

High-throughput

0.437

High

672689

NOL10
Ribosome biogenesis protein ENP2

1

2

High-throughput

0.437

High

672692

CCH1
Calcium-channel protein CCH1

1

1

High-throughput

0.437

High

672697

SPC98
Spindle pole body component SPC98

1

11

High-throughput

0.437

High

672706

H3
Histone H3

1

6

High-throughput

0.437

High

672736

WDR6
tRNA

1

16

High-throughput

0.437

High

672739

PLP2
Phosducin-like protein 2

1

4

High-throughput

0.437

High

672744

NAA25
N-terminal acetyltransferase B complex subunit MDM20

1

2

High-throughput

0.437

High

672746

CEX1
Cytoplasmic export protein 1

1

1

High-throughput

0.437

High

672750

ATC8
Probable phospholipid-transporting ATPase DNF3

1

1

High-throughput

0.437

High

672733

DPP3
Probable dipeptidyl peptidase 3

1

0

High-throughput

0.269

Low

550570

SST2
Protein SST2

1

0

High-throughput

0.249

Low

672603

NPP1
Ectonucleotide pyrophosphatase/phosphodiesterase 1

1

0

High-throughput

0.249

Low

672628

PYRD
Dihydroorotate dehydrogenase

1

0

High-throughput

0.249

Low

672633

KA122
Importin beta-like protein KAP122

1

0

High-throughput

0.249

Low

672636

SKG6
Protein SKG6

1

0

High-throughput

0.249

Low

672637

SPT4
Transcription elongation factor SPT4

1

0

High-throughput

0.249

Low

672644

NNRD
ATP-dependent

1

0

High-throughput

0.249

Low

672646

JNM1
Nuclear migration protein JNM1

1

0

High-throughput

0.249

Low

672655

INM1
Inositol monophosphatase 1

1

0

High-throughput

0.249

Low

672656

YAP3
AP-1-like transcription factor YAP3

1

0

High-throughput

0.249

Low

672659

TDA11
Topoisomerase I damage affected protein 11

1

0

High-throughput

0.249

Low

672665

PHO90
Low-affinity phosphate transporter PHO90

1

0

High-throughput

0.249

Low

672666

FLC2
Flavin carrier protein 2

1

0

High-throughput

0.249

Low

672668

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.249

Low

672669

YND1
Golgi apyrase

1

0

High-throughput

0.249

Low

672672

LDO45
Lipid droplet organization protein LDO45

1

0

High-throughput

0.249

Low

672674

PRM5
Pheromone-regulated membrane protein 5

1

0

High-throughput

0.249

Low

672678

SKP2
F-box protein SKP2

1

0

High-throughput

0.249

Low

672679

SERB
Phosphoserine phosphatase

1

0

High-throughput

0.249

Low

672683

BUD27
Bud site selection protein 27

1

0

High-throughput

0.249

Low

672693

RIB4
6,7-dimethyl-8-ribityllumazine synthase

1

0

High-throughput

0.249

Low

672694

PSD2
Phosphatidylserine decarboxylase proenzyme 2

1

0

High-throughput

0.249

Low

672699

MDG1
Signal transduction protein MDG1

1

0

High-throughput

0.249

Low

672700

BNI5
Bud neck protein 5

1

0

High-throughput

0.249

Low

672701

AQR1
Probable transporter AQR1

1

0

High-throughput

0.249

Low

672707

MCE1
mRNA-capping enzyme subunit alpha

1

0

High-throughput

0.249

Low

672710

YMY9
Glucose-6-phosphate 1-epimerase

1

0

High-throughput

0.249

Low

672712

YMC0
Uncharacterized protein YML020W

1

0

High-throughput

0.249

Low

672716

CSI1
Cop9 signalosome-interactor 1

1

0

High-throughput

0.249

Low

672719

TVP18
Golgi apparatus membrane protein TVP18

1

0

High-throughput

0.249

Low

672722

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.249

Low

672724

BSP1
F-actin capping regulator BSP1

1

0

High-throughput

0.249

Low

672727

VPS36
Vacuolar protein-sorting-associated protein 36

1

0

High-throughput

0.249

Low

672734

CUE5
Ubiquitin-binding protein CUE5

1

0

High-throughput

0.249

Low

672738

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

0

High-throughput

0.249

Low

672740

RCN2
Regulator of calcineurin 2

1

0

High-throughput

0.249

Low

672748

AVL9
Late secretory pathway protein AVL9

1

0

High-throughput

0.249

Low

672751

YCB2
UPF0357 protein YCL012C

1

0

High-throughput

0.249

Low

672717

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025