Protein: EI2BE
Translation initiation factor eIF2B subunit epsilon (eIF2B GDP-GTP exchange factor subunit epsilon)

Gene: EI2BE, EIF2B5
Organism: Homo sapiens
Interactions: 153
UniProt ID: Q13144

Gene Ontology (top 5):
GO:0001541 - ovarian follicle development
GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1025629

EI2BA
Translation initiation factor eIF2B subunit alpha

5

18

Small-scale

0.716

High

834408

EI2BB
Translation initiation factor eIF2B subunit beta

4

18

Small-scale

0.696

High

1025688

OPN3
Opsin-3

3

7

High-throughput

0.667

High

1025701

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

1

High-throughput

0.667

High

1025703

EI2BD
Translation initiation factor eIF2B subunit delta

3

15

Small-scale

0.660

High

599568

SYT1
Synaptotagmin-1

2

3

High-throughput

0.628

High

1025658

UXS1
UDP-glucuronic acid decarboxylase 1

2

1

High-throughput

0.628

High

1025706

FZD10
Frizzled-10

2

1

High-throughput

0.628

High

1025697

EI2BG
Translation initiation factor eIF2B subunit gamma

2

17

Small-scale

0.619

High

686799

GP183
G-protein coupled receptor 183

3

10

High-throughput

0.609

High

793097

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

6

High-throughput

0.609

High

1025650

STX12
Syntaxin-12

3

2

High-throughput

0.609

High

1025683

P2RX4
P2X purinoceptor 4

3

1

High-throughput

0.609

High

1025707

CAH14
Carbonic anhydrase 14

3

1

High-throughput

0.609

High

269413

STX11
Syntaxin-11

3

3

High-throughput

0.607

High

835714

GSK3B
Glycogen synthase kinase-3 beta

2

5

Small-scale

0.602

High

227333

PRKN
E3 ubiquitin-protein ligase parkin

2

10

High-throughput

0.584

High

338359

EGFR
Epidermal growth factor receptor

2

4

High-throughput

0.584

High

50137

HACL2
2-hydroxyacyl-CoA lyase 2

2

5

High-throughput

0.574

High

409772

GLPB
Glycophorin-B

2

4

High-throughput

0.574

High

600565

EPHA1
Ephrin type-A receptor 1

2

2

High-throughput

0.574

High

1025656

SIGL1
SIGLEC family-like protein 1

2

2

High-throughput

0.574

High

1025691

PACC1
Proton-activated chloride channel

2

3

High-throughput

0.574

High

556504

LEUK
Leukosialin

2

1

High-throughput

0.558

High

713387

CD68
Macrosialin

2

1

High-throughput

0.558

High

1025648

CMTD1
Catechol O-methyltransferase domain-containing protein 1

2

3

High-throughput

0.558

High

207234

TNF14
Tumor necrosis factor ligand superfamily member 14

1

1

High-throughput

0.536

High

308670

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.536

High

328325

S1PR4
Sphingosine 1-phosphate receptor 4

1

1

High-throughput

0.536

High

380286

HG2A
HLA class II histocompatibility antigen gamma chain

1

2

High-throughput

0.536

High

428578

INVO
Involucrin

1

1

High-throughput

0.536

High

454696

TACD2
Tumor-associated calcium signal transducer 2

1

1

High-throughput

0.536

High

780692

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

11

High-throughput

0.536

High

865037

TTC3
E3 ubiquitin-protein ligase TTC3

1

9

High-throughput

0.536

High

907879

RS16
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

949009

HTRA4
Serine protease HTRA4

1

2

High-throughput

0.536

High

957829

EFNB1
Ephrin-B1

1

5

High-throughput

0.536

High

997147

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

3

High-throughput

0.536

High

1025625

MYO9B
Unconventional myosin-IXb

1

4

High-throughput

0.536

High

1025633

MA7D1
MAP7 domain-containing protein 1

1

1

High-throughput

0.536

High

1025634

CEP78
Centrosomal protein of 78 kDa

1

1

High-throughput

0.536

High

1025640

S27A4
Long-chain fatty acid transport protein 4

1

2

High-throughput

0.536

High

1025643

BTNL9
Butyrophilin-like protein 9

1

3

High-throughput

0.536

High

1025653

ASPM
Abnormal spindle-like microcephaly-associated protein

1

4

High-throughput

0.536

High

1025666

FGF14
Fibroblast growth factor 14

1

1

High-throughput

0.536

High

1025673

GMPPA
Mannose-1-phosphate guanyltransferase alpha

1

16

High-throughput

0.536

High

1025676

F210A
Protein FAM210A

1

1

High-throughput

0.536

High

1025686

OSBL8
Oxysterol-binding protein-related protein 8

1

1

High-throughput

0.536

High

1025695

MYO5C
Unconventional myosin-Vc

1

3

High-throughput

0.536

High

1025696

ASH1L
Histone-lysine N-methyltransferase ASH1L

1

2

High-throughput

0.536

High

1025711

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

2

High-throughput

0.536

High

1025712

EXOG
Nuclease EXOG, mitochondrial

1

2

High-throughput

0.536

High

1025713

MYO5A
Unconventional myosin-Va

1

3

High-throughput

0.536

High

1025715

GMPPB
Mannose-1-phosphate guanyltransferase beta

1

17

High-throughput

0.536

High

779338

CCNF
Cyclin-F

1

5

High-throughput

0.515

High

1025628

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

1

High-throughput

0.515

High

1025664

KLK6
Kallikrein-6

1

1

High-throughput

0.515

High

183370

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

High-throughput

0.513

High

416416

S10A9
Protein S100-A9

1

0

High-throughput

0.513

High

477762

ZN865
Zinc finger protein 865

1

0

High-throughput

0.513

High

814940

LEG7
Galectin-7

1

0

High-throughput

0.513

High

887232

ZN445
Zinc finger protein 445

1

0

High-throughput

0.513

High

1025630

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

1025641

LTMD1
LETM1 domain-containing protein 1

1

0

High-throughput

0.513

High

1025645

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.513

High

1025694

INCE
Inner centromere protein

1

0

High-throughput

0.513

High

1025710

PIN4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

1

0

High-throughput

0.513

High

208831

CHM2A
Charged multivesicular body protein 2a

1

1

High-throughput

0.508

High

1025627

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

Small-scale

0.501

High

1025663

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

6

Small-scale

0.501

High

129389

GOLI4
Golgi integral membrane protein 4

1

2

High-throughput

0.489

High

156825

FFAR1
Free fatty acid receptor 1

1

10

High-throughput

0.489

High

238608

PEX10
Peroxisome biogenesis factor 10

1

1

High-throughput

0.489

High

238862

TPST2
Protein-tyrosine sulfotransferase 2

1

1

High-throughput

0.489

High

314984

SGPL1
Sphingosine-1-phosphate lyase 1

1

1

High-throughput

0.489

High

626780

PTAFR
Platelet-activating factor receptor

1

9

High-throughput

0.489

High

666309

NK3R
Neuromedin-K receptor

1

3

High-throughput

0.489

High

702219

CD70
CD70 antigen

1

1

High-throughput

0.489

High

714914

BTC
Probetacellulin [Cleaved into: Betacellulin

1

2

High-throughput

0.489

High

1025623

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

12

High-throughput

0.489

High

1025624

PLD1
Phospholipase D1

1

1

High-throughput

0.489

High

1025631

P2RY6
P2Y purinoceptor 6

1

10

High-throughput

0.489

High

1025632

CD226
CD226 antigen

1

4

High-throughput

0.489

High

1025636

ATD3B
ATPase family AAA domain-containing protein 3B

1

4

High-throughput

0.489

High

1025638

PHLB3
Pleckstrin homology-like domain family B member 3

1

2

High-throughput

0.489

High

1025647

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

3

High-throughput

0.489

High

1025649

CHSS1
Chondroitin sulfate synthase 1

1

1

High-throughput

0.489

High

1025655

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

3

High-throughput

0.489

High

1025657

SYT2
Synaptotagmin-2

1

3

High-throughput

0.489

High

1025662

CLC2B
C-type lectin domain family 2 member B

1

2

High-throughput

0.489

High

1025671

TV23C
Golgi apparatus membrane protein TVP23 homolog C

1

1

High-throughput

0.489

High

1025674

F210B
Protein FAM210B, mitochondrial

1

1

High-throughput

0.489

High

1025675

B3GT6
Beta-1,3-galactosyltransferase 6

1

1

High-throughput

0.489

High

1025677

NECT4
Nectin-4

1

2

High-throughput

0.489

High

1025678

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

2

High-throughput

0.489

High

1025680

MA7D2
MAP7 domain-containing protein 2

1

4

High-throughput

0.489

High

1025682

SEC62
Translocation protein SEC62

1

1

High-throughput

0.489

High

1025687

UN93B
Protein unc-93 homolog B1

1

2

High-throughput

0.489

High

1025692

PCDH9
Protocadherin-9

1

1

High-throughput

0.489

High

1025698

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

1

1

High-throughput

0.489

High

1025700

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

1

High-throughput

0.489

High

1025704

CC018
Uncharacterized protein C3orf18

1

2

High-throughput

0.489

High

1025714

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

1

High-throughput

0.489

High

1025716

GPR45
Probable G-protein coupled receptor 45

1

2

High-throughput

0.489

High

394641

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

162689

XPO1
Exportin-1

1

8

High-throughput

0.479

High

322555

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

346676

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

552619

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

651092

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

874496

XPO2
Exportin-2

1

7

High-throughput

0.479

High

882275

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.479

High

903187

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.479

High

1025626

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1025637

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.479

High

1025644

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

1025646

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1025654

PNKD
Probable hydrolase PNKD

1

2

High-throughput

0.479

High

1025667

FBXW7
F-box/WD repeat-containing protein 7

1

4

High-throughput

0.479

High

1025669

LRC59
Leucine-rich repeat-containing protein 59

1

2

High-throughput

0.479

High

1025672

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.479

High

1025690

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.479

High

1025699

TLS1
Splicing factor C9orf78

1

4

High-throughput

0.479

High

1025702

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1025670

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

401929

JUN
Transcription factor Jun

1

6

High-throughput

0.445

High

496947

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High

1025635

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

1025679

CK5P2
CDK5 regulatory subunit-associated protein 2

1

3

High-throughput

0.445

High

384758

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.437

High

720357

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

856530

EFNB2
Ephrin-B2

1

5

High-throughput

0.437

High

1025642

LMBRL
Protein LMBR1L

1

5

High-throughput

0.437

High

1025651

S15A3
Solute carrier family 15 member 3

1

3

High-throughput

0.437

High

1025689

EMRE
Essential MCU regulator, mitochondrial

1

2

High-throughput

0.437

High

1025705

HECD1
E3 ubiquitin-protein ligase HECTD1

1

7

High-throughput

0.437

High

99593

F5H1C8
Solute carrier family 15 member 3

1

3

High-throughput

0.407

High

1025668

IGSF8
Immunoglobulin superfamily member 8

2

0

High-throughput

0.318

High

639579

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.279

Low

872910

ARSF
Arylsulfatase F

1

0

High-throughput

0.279

Low

1025639

M18BP
Mis18-binding protein 1

1

0

High-throughput

0.279

Low

1025652

TM192
Transmembrane protein 192

1

0

High-throughput

0.279

Low

1025660

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1025661

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

1025665

GSLG1
Golgi apparatus protein 1

1

0

High-throughput

0.279

Low

1025681

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

High-throughput

0.279

Low

1025684

MICU1
Calcium uptake protein 1, mitochondrial

1

0

High-throughput

0.279

Low

1025685

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.279

Low

1025693

JPH1
Junctophilin-1

1

0

High-throughput

0.279

Low

1025708

CLC4A
C-type lectin domain family 4 member A

1

0

High-throughput

0.279

Low

1025709

STX8
Syntaxin-8

1

0

High-throughput

0.279

Low

100723

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1025659

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024