Protein: RLGPB
Ral GTPase-activating protein subunit beta (p170)

Gene: RLGPB, RALGAPB
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q86X10

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0032484 - Ral protein signal transduction
GO:0046982 - protein heterodimerization activity
GO:0051056 - regulation of small GTPase mediated signal transduction
GO:0090630 - activation of GTPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1293046

KBRS2
NF-kappa-B inhibitor-interacting Ras-like protein 2

3

8

High-throughput

0.662

High

1293045

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

4

2

High-throughput

0.630

High

1293039

DPH7
Diphthine methyltransferase

2

2

High-throughput

0.574

High

1293049

FBW1A
F-box/WD repeat-containing protein 1A

2

1

High-throughput

0.574

High

989035

AP2B1
AP-2 complex subunit beta

2

1

High-throughput

0.558

High

1293044

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

2

3

High-throughput

0.553

High

971736

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.536

High

540539

LAMP1
Lysosome-associated membrane glycoprotein 1

2

8

High-throughput

0.533

High

976381

RB11A
Ras-related protein Rab-11A

2

3

High-throughput

0.533

High

978129

RHOB
Rho-related GTP-binding protein RhoB

2

18

High-throughput

0.533

High

396443

ESR1
Estrogen receptor

2

2

High-throughput

0.521

High

990447

1433Z
14-3-3 protein zeta/delta

1

11

High-throughput

0.489

High

1159937

MEA1
Male-enhanced antigen 1

1

1

High-throughput

0.489

High

1293032

DLG3
Disks large homolog 3

1

2

High-throughput

0.489

High

1293038

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

1

High-throughput

0.489

High

1293050

PARP3
Protein mono-ADP-ribosyltransferase PARP3

1

1

High-throughput

0.489

High

126677

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

710341

EPHA2
Ephrin type-A receptor 2

1

2

High-throughput

0.479

High

1015570

RHOG
Rho-related GTP-binding protein RhoG

1

13

High-throughput

0.479

High

1049513

1433F
14-3-3 protein eta

1

11

High-throughput

0.479

High

1270884

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1293043

RHOF
Rho-related GTP-binding protein RhoF

1

19

High-throughput

0.479

High

1179626

RGPA2
Ral GTPase-activating protein subunit alpha-2

1

1

Small-scale

0.445

High

1233129

RGPA1
Ral GTPase-activating protein subunit alpha-1

1

1

Small-scale

0.445

High

1259318

TBA1A
Tubulin alpha-1A chain

1

1

Small-scale

0.445

High

189673

STX7
Syntaxin-7

1

1

High-throughput

0.437

High

226105

STX6
Syntaxin-6

1

1

High-throughput

0.437

High

412202

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

562186

LAMP2
Lysosome-associated membrane glycoprotein 2

1

8

High-throughput

0.437

High

601355

RHOQ
Rho-related GTP-binding protein RhoQ

1

19

High-throughput

0.437

High

630865

RAB4A
Ras-related protein Rab-4A

1

6

High-throughput

0.437

High

730021

1433B
14-3-3 protein beta/alpha

1

11

High-throughput

0.437

High

901912

RAB9A
Ras-related protein Rab-9A

1

7

High-throughput

0.437

High

910117

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.437

High

953541

RAC3
Ras-related C3 botulinum toxin substrate 3

1

16

High-throughput

0.437

High

955342

CDC42
Cell division control protein 42 homolog

1

18

High-throughput

0.437

High

962230

RHOA
Transforming protein RhoA

1

15

High-throughput

0.437

High

966565

1433G
14-3-3 protein gamma

1

11

High-throughput

0.437

High

988497

RAC1
Ras-related C3 botulinum toxin substrate 1

1

16

High-throughput

0.437

High

1135353

SLMAP
Sarcolemmal membrane-associated protein

1

3

High-throughput

0.437

High

1151758

RHOH
Rho-related GTP-binding protein RhoH

1

18

High-throughput

0.437

High

1254482

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1293031

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

1293033

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.437

High

1293035

RHOV
Rho-related GTP-binding protein RhoV

1

19

High-throughput

0.437

High

1293040

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.437

High

1293041

RHOJ
Rho-related GTP-binding protein RhoJ

1

19

High-throughput

0.437

High

1293048

LAMP3
Lysosome-associated membrane glycoprotein 3

1

8

High-throughput

0.437

High

1293034

NEUL4
Neuralized-like protein 4

1

1

High-throughput

0.407

High

1293030

DND1
Dead end protein homolog 1

3

0

High-throughput

0.347

High

424521

PAI2
Plasminogen activator inhibitor 2

2

0

High-throughput

0.328

High

1293037

CD006
Uncharacterized protein encoded by LINC01587

2

0

High-throughput

0.318

High

1253625

PKHG7
Pleckstrin homology domain-containing family G member 7

2

0

High-throughput

0.288

High

49994

IRGM
Immunity-related GTPase family M protein

1

0

High-throughput

0.279

Low

1103097

MFAP5
Microfibrillar-associated protein 5

1

0

High-throughput

0.279

Low

1293036

TMM74
Transmembrane protein 74

1

0

High-throughput

0.279

Low

1293047

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

0

High-throughput

0.279

Low

218407

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

459661

PROF1
Profilin-1

1

0

High-throughput

0.249

Low

557367

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.249

Low

1252726

GBP6
Guanylate-binding protein 6

1

0

High-throughput

0.249

Low

1276437

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1293042

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

207577

DHX15
ATP-dependent RNA helicase DHX15

1

0

Small-scale

0.232

Low

457533

TBB5
Tubulin beta chain

1

0

Small-scale

0.232

Low

996226

EF1A1
Elongation factor 1-alpha 1

1

0

Small-scale

0.232

Low

1155001

ADIPO
Adiponectin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025