Protein: PTPRC
Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (Lymphocyte antigen 5) (Ly-5) (T200) (CD antigen CD45)

Gene: PTPRC
Organism: Mus musculus
Interactions: 13
UniProt ID: P06800

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0001779 - natural killer cell differentiation
GO:0001915 - negative regulation of T cell mediated cytotoxicity
GO:0001916 - positive regulation of T cell mediated cytotoxicity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

440267

LCK
Proto-oncogene tyrosine-protein kinase LCK

2

20

Small-scale

0.712

High

449213

VAV
Proto-oncogene vav

1

13

Small-scale

0.575

High

449217

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.575

High

449222

Q91YX7
Ras GTPase-activating protein 1

1

11

Small-scale

0.575

High

449215

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

1

High-throughput

0.479

High

449218

MRC1
Macrophage mannose receptor 1

1

4

Small-scale

0.479

High

449211

CD44
CD44 antigen

1

2

Small-scale

0.445

High

449212

CBL
E3 ubiquitin-protein ligase CBL

1

9

High-throughput

0.445

High

449216

CARL2
Capping protein, Arp2/3 and myosin-I linker protein 2

1

2

Small-scale

0.445

High

449220

SOS1
Son of sevenless homolog 1

1

4

Small-scale

0.445

High

449221

PTCA
Protein tyrosine phosphatase receptor type C-associated protein

1

1

Small-scale

0.445

High

449219

JAK2
Tyrosine-protein kinase JAK2

1

20

Small-scale

0.436

High

449214

JAK1
Tyrosine-protein kinase JAK1

1

20

Small-scale

0.390

High


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Last updated: 11Aug2025