Protein: IRS2
Insulin receptor substrate 2 (IRS-2) (4PS)

Gene: IRS2
Organism: Mus musculus
Interactions: 11
UniProt ID: P81122

Gene Ontology (top 5):
GO:0002053 - positive regulation of mesenchymal cell proliferation
GO:0002903 - negative regulation of B cell apoptotic process
GO:0005068 - transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005158 - insulin receptor binding
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

686950

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

3

20

Small-scale

0.640

High

772547

IRS1
Insulin receptor substrate 1

1

13

Small-scale

0.618

High

1010411

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.618

High

1010412

GRB10
Growth factor receptor-bound protein 10

1

20

Small-scale

0.618

High

1010415

PHIP
PH-interacting protein

1

14

Small-scale

0.618

High

1010414

LONM
Lon protease homolog, mitochondrial

1

6

Small-scale

0.506

High

594824

IL4RA
Interleukin-4 receptor subunit alpha

1

3

Small-scale

0.479

High

1010416

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

11

Small-scale

0.479

High

480968

NUCL
Nucleolin

1

10

Small-scale

0.462

High

1010413

ZN592
Zinc finger protein 592

1

3

Small-scale

0.462

High

683092

LYN
Tyrosine-protein kinase Lyn

1

19

Small-scale

0.436

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025