Interactor 1: IRS1 (P35569)
Insulin receptor substrate 1 (IRS-1)
Gene: IRS1
Interactor 2: IRS2 (P81122)
Insulin receptor substrate 2 (IRS-2) (4PS)
Gene: IRS2
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9729467 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IRS~IRS, IRS~PH, PH~PH |
| Common GO terms | GO:0002053 - positive regulation of mesenchymal cell proliferation GO:0005068 - transmembrane receptor protein tyrosine kinase adaptor activity GO:0005158 - insulin receptor binding GO:0005829 - cytosol GO:0005886 - plasma membrane and 12 others more... |
| Homologous interactions | 13 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
