Protein: DESI2
Deubiquitinase DESI2 (EC 3.4.19.12) (Desumoylating isopeptidase 2) (DeSI-2) (PPPDE peptidase domain-containing protein 1) (Palmitoyl protein thioesterase DESI2) (EC 3.1.2.22) (Protein FAM152A) (S-depalmitoylase DESI2)

Gene: DESI2
Organism: Homo sapiens
Interactions: 15
UniProt ID: Q9BSY9

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005737 - cytoplasm
GO:0006508 - proteolysis
GO:0008474 - palmitoyl-(protein) hydrolase activity
GO:0052816 - long-chain fatty acyl-CoA hydrolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1092032

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

2

0

High-throughput

0.580

High

1322306

SPART
Spartin

2

0

High-throughput

0.580

High

1412960

SHLB1
Endophilin-B1

2

0

High-throughput

0.580

High

1412959

NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

2

1

High-throughput

0.553

High

1315837

AN13A
Ankyrin repeat domain-containing protein 13A

1

1

High-throughput

0.536

High

1412957

MYG1
MYG1 exonuclease

1

0

High-throughput

0.493

High

1383345

Q96AL5
PBX3 protein

1

1

High-throughput

0.470

High

823978

PBX3
Pre-B-cell leukemia transcription factor 3

1

1

High-throughput

0.439

High

920649

ARFP1
Arfaptin-1

2

0

High-throughput

0.316

High

1341307

COQ8A
Atypical kinase COQ8A, mitochondrial

2

0

High-throughput

0.316

High

1405113

PLIN2
Perilipin-2

2

0

High-throughput

0.316

High

1412956

THAP7
THAP domain-containing protein 7

2

0

High-throughput

0.316

High

1412958

SEM3G
Semaphorin-3G

2

0

High-throughput

0.316

High

787241

BMR1A
Bone morphogenetic protein receptor type-1A

1

0

High-throughput

0.279

Low

516929

CB27B
Putative uncharacterized protein CDRT15P3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025