Protein: KLF12
Krueppel-like factor 12 (Transcriptional repressor AP-2rep)

Gene: KLF12
Organism: Homo sapiens
Interactions: 189
UniProt ID: Q9Y4X4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1032712

CTBP1
C-terminal-binding protein 1

4

12

High-throughput

0.709

High

1296448

EHMT2
Histone-lysine N-methyltransferase EHMT2

4

20

High-throughput

0.694

High

1050852

FHL2
Four and a half LIM domains protein 2

3

20

High-throughput

0.665

High

167179

ZN536
Zinc finger protein 536

1

19

High-throughput

0.618

High

215941

ZBT14
Zinc finger and BTB domain-containing protein 14

1

20

High-throughput

0.618

High

231263

ZEB2
Zinc finger E-box-binding homeobox 2

1

20

High-throughput

0.618

High

260406

ZN217
Zinc finger protein 217

1

20

High-throughput

0.618

High

550449

ZEP1
Zinc finger protein 40

1

20

High-throughput

0.618

High

632964

TYY1
Transcriptional repressor protein YY1

1

19

High-throughput

0.618

High

741108

ZEB1
Zinc finger E-box-binding homeobox 1

1

20

High-throughput

0.618

High

831095

CTCF
Transcriptional repressor CTCF

1

20

High-throughput

0.618

High

855964

ZN131
Zinc finger protein 131

1

20

High-throughput

0.618

High

974714

MECOM
Histone-lysine N-methyltransferase MECOM

1

20

High-throughput

0.618

High

1022809

PRDM2
PR domain zinc finger protein 2

1

18

High-throughput

0.618

High

1268314

ZN516
Zinc finger protein 516

1

20

High-throughput

0.618

High

1270343

RREB1
Ras-responsive element-binding protein 1

1

20

High-throughput

0.618

High

1281590

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

1

20

High-throughput

0.618

High

1296276

Z512B
Zinc finger protein 512B

1

18

High-throughput

0.618

High

1297819

ZN512
Zinc finger protein 512

1

20

High-throughput

0.618

High

1331909

ZN644
Zinc finger protein 644

1

19

High-throughput

0.618

High

1335053

PRD16
Histone-lysine N-methyltransferase PRDM16

1

20

High-throughput

0.618

High

1357927

ZN148
Zinc finger protein 148

1

20

High-throughput

0.618

High

1377474

ZN281
Zinc finger protein 281

1

20

High-throughput

0.618

High

1044744

FHL3
Four and a half LIM domains protein 3

2

16

High-throughput

0.606

High

396118

A4
Amyloid-beta precursor protein

2

18

High-throughput

0.602

High

1169855

I23O2
Indoleamine 2,3-dioxygenase 2

2

0

High-throughput

0.602

High

1346934

THAP1
THAP domain-containing protein 1

1

5

High-throughput

0.573

High

323366

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

17

High-throughput

0.536

High

846282

RT29
Small ribosomal subunit protein mS29

1

3

High-throughput

0.536

High

948142

RT15
Small ribosomal subunit protein uS15m

1

3

High-throughput

0.536

High

1184110

DHX30
ATP-dependent RNA helicase DHX30

1

5

High-throughput

0.536

High

1290681

PTCD3
Small ribosomal subunit protein mS39

1

3

High-throughput

0.536

High

1377658

RT16
Small ribosomal subunit protein bS16m

1

2

High-throughput

0.536

High

1317193

RT26
Small ribosomal subunit protein mS26

1

3

High-throughput

0.515

High

614464

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.515

High

792129

HD
Huntingtin

1

11

High-throughput

0.515

High

905307

1433G
14-3-3 protein gamma

1

5

High-throughput

0.515

High

1065764

SETB1
Histone-lysine N-methyltransferase SETDB1

1

20

High-throughput

0.515

High

1251497

LMO3
LIM domain only protein 3

1

14

High-throughput

0.515

High

1273546

KAT5
Histone acetyltransferase KAT5

1

6

High-throughput

0.515

High

1273990

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

12

High-throughput

0.501

High

133750

NOP56
Nucleolar protein 56

1

5

High-throughput

0.500

High

403380

LA
Lupus La protein

1

11

High-throughput

0.500

High

518805

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.500

High

932076

TPM4
Tropomyosin alpha-4 chain

1

11

High-throughput

0.500

High

1057748

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

12

High-throughput

0.500

High

1131435

HP1B3
Heterochromatin protein 1-binding protein 3

1

2

High-throughput

0.500

High

1254856

DDX54
ATP-dependent RNA helicase DDX54

1

12

High-throughput

0.500

High

1312975

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

11

High-throughput

0.500

High

1377908

RT18B
Small ribosomal subunit protein mS40

1

5

High-throughput

0.500

High

241123

RT14
Small ribosomal subunit protein uS14m

1

4

High-throughput

0.489

High

947018

RT22
Small ribosomal subunit protein mS22

1

3

High-throughput

0.489

High

947195

RT25
Small ribosomal subunit protein mS25

1

2

High-throughput

0.489

High

947531

RT35
Small ribosomal subunit protein mS35

1

4

High-throughput

0.489

High

947705

RT05
Small ribosomal subunit protein uS5m

1

6

High-throughput

0.489

High

948047

RT11
Small ribosomal subunit protein uS11m

1

3

High-throughput

0.489

High

948410

RT34
Small ribosomal subunit protein mS34

1

4

High-throughput

0.489

High

948770

RT09
Small ribosomal subunit protein uS9m

1

10

High-throughput

0.489

High

1267014

RT27
Small ribosomal subunit protein mS27

1

3

High-throughput

0.489

High

1268836

RT31
Small ribosomal subunit protein mS31

1

3

High-throughput

0.489

High

1289933

RT24
Small ribosomal subunit protein uS3m

1

2

High-throughput

0.489

High

1326389

DDX24
ATP-dependent RNA helicase DDX24

1

15

High-throughput

0.489

High

1330074

CPVL
Probable serine carboxypeptidase CPVL

1

4

High-throughput

0.489

High

1377380

RT07
Small ribosomal subunit protein uS7m

1

10

High-throughput

0.489

High

1377570

RT02
Small ribosomal subunit protein uS2m

1

5

High-throughput

0.489

High

1377612

RM11
Large ribosomal subunit protein uL11m

1

2

High-throughput

0.489

High

1377676

RT23
Small ribosomal subunit protein mS23

1

4

High-throughput

0.489

High

1356097

DNM3L
DNA

1

0

Small-scale

0.480

High

1133991

RM02
Large ribosomal subunit protein uL2m

1

0

High-throughput

0.479

High

1235054

RM50
Large ribosomal subunit protein mL50

1

0

High-throughput

0.479

High

128352

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

11

High-throughput

0.479

High

135179

NFIB
Nuclear factor 1 B-type

1

14

High-throughput

0.479

High

165744

SET1A
Histone-lysine N-methyltransferase SETD1A

1

20

High-throughput

0.479

High

265738

E2F6
Transcription factor E2F6

1

13

High-throughput

0.479

High

266460

TAD2A
Transcriptional adapter 2-alpha

1

16

High-throughput

0.479

High

267723

TADA3
Transcriptional adapter 3

1

5

High-throughput

0.479

High

321859

WIZ
Protein Wiz

1

20

High-throughput

0.479

High

525337

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

20

High-throughput

0.479

High

585680

TFE3
Transcription factor E3

1

12

High-throughput

0.479

High

610194

RFX1
MHC class II regulatory factor RFX1

1

13

High-throughput

0.479

High

666554

KDM5A
Lysine-specific demethylase 5A

1

7

High-throughput

0.479

High

773650

RL13A
Large ribosomal subunit protein uL13

1

5

High-throughput

0.479

High

806747

RL28
Large ribosomal subunit protein eL28

1

6

High-throughput

0.479

High

824584

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

20

High-throughput

0.479

High

836274

TAF6
Transcription initiation factor TFIID subunit 6

1

4

High-throughput

0.479

High

839252

EMD
Emerin

1

10

High-throughput

0.479

High

867674

BLM
RecQ-like DNA helicase BLM

1

9

High-throughput

0.479

High

868824

ATX1
Ataxin-1

1

8

High-throughput

0.479

High

881352

CTBP2
C-terminal-binding protein 2

1

12

High-throughput

0.479

High

898807

RL26
Large ribosomal subunit protein uL24

1

11

High-throughput

0.479

High

903644

WDR5
WD repeat-containing protein 5

1

16

High-throughput

0.479

High

920412

RS24
Small ribosomal subunit protein eS24

1

2

High-throughput

0.479

High

922097

RL39
Large ribosomal subunit protein eL39

1

4

High-throughput

0.479

High

952903

FOXK1
Forkhead box protein K1

1

16

High-throughput

0.479

High

959108

TFAM
Transcription factor A, mitochondrial

1

18

High-throughput

0.479

High

975354

KMT2A
Histone-lysine N-methyltransferase 2A

1

20

High-throughput

0.479

High

980959

TLE4
Transducin-like enhancer protein 4

1

20

High-throughput

0.479

High

987811

GABPA
GA-binding protein alpha chain

1

20

High-throughput

0.479

High

1016461

TF3C1
General transcription factor 3C polypeptide 1

1

2

High-throughput

0.479

High

1018285

NFIA
Nuclear factor 1 A-type

1

17

High-throughput

0.479

High

1018773

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

17

High-throughput

0.479

High

1040743

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.479

High

1050551

TFDP1
Transcription factor Dp-1

1

3

High-throughput

0.479

High

1051272

ZMYM3
Zinc finger MYM-type protein 3

1

17

High-throughput

0.479

High

1057439

SMC1A
Structural maintenance of chromosomes protein 1A

1

7

High-throughput

0.479

High

1058079

RRP5
Protein RRP5 homolog

1

8

High-throughput

0.479

High

1077627

ELF2
ETS-related transcription factor Elf-2

1

20

High-throughput

0.479

High

1079919

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

5

High-throughput

0.479

High

1117722

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

1129674

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

12

High-throughput

0.479

High

1154435

LIN54
Protein lin-54 homolog

1

4

High-throughput

0.479

High

1167140

MCAF1
Activating transcription factor 7-interacting protein 1

1

19

High-throughput

0.479

High

1167350

BCOR
BCL-6 corepressor

1

18

High-throughput

0.479

High

1190890

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

20

High-throughput

0.479

High

1199221

PB1
Protein polybromo-1

1

20

High-throughput

0.479

High

1205841

P66A
Transcriptional repressor p66-alpha

1

2

High-throughput

0.479

High

1218114

ARI3B
AT-rich interactive domain-containing protein 3B

1

20

High-throughput

0.479

High

1218740

MGAP
MAX gene-associated protein

1

11

High-throughput

0.479

High

1223218

ZZZ3
ZZ-type zinc finger-containing protein 3

1

2

High-throughput

0.479

High

1233287

RYBP
RING1 and YY1-binding protein

1

4

High-throughput

0.479

High

1245611

KDM2B
Lysine-specific demethylase 2B

1

11

High-throughput

0.479

High

1254448

CHD6
Chromodomain-helicase-DNA-binding protein 6

1

17

High-throughput

0.479

High

1255863

MORC4
MORC family CW-type zinc finger protein 4

1

2

High-throughput

0.479

High

1260566

GATD1
GATA zinc finger domain-containing protein 1

1

5

High-throughput

0.479

High

1271475

KAT2A
Histone acetyltransferase KAT2A

1

20

High-throughput

0.479

High

1271520

KAT2B
Histone acetyltransferase KAT2B

1

20

High-throughput

0.479

High

1282181

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

13

High-throughput

0.479

High

1286170

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

20

High-throughput

0.479

High

1295456

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

17

High-throughput

0.479

High

1296862

EP400
E1A-binding protein p400

1

20

High-throughput

0.479

High

1300628

PHF12
PHD finger protein 12

1

20

High-throughput

0.479

High

1301020

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1304215

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1306906

ARI3A
AT-rich interactive domain-containing protein 3A

1

20

High-throughput

0.479

High

1311564

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.479

High

1312050

MTA3
Metastasis-associated protein MTA3

1

18

High-throughput

0.479

High

1316719

PCGF6
Polycomb group RING finger protein 6

1

20

High-throughput

0.479

High

1317942

GTPB4
GTP-binding protein 4

1

7

High-throughput

0.479

High

1326291

REXO4
RNA exonuclease 4

1

4

High-throughput

0.479

High

1327816

RGAP1
Rac GTPase-activating protein 1

1

18

High-throughput

0.479

High

1329359

EPC1
Enhancer of polycomb homolog 1

1

10

High-throughput

0.479

High

1331089

ZHX3
Zinc fingers and homeoboxes protein 3

1

20

High-throughput

0.479

High

1333510

CSR2B
Cysteine-rich protein 2-binding protein

1

1

High-throughput

0.479

High

1334147

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

20

High-throughput

0.479

High

1334271

ARP5
Actin-related protein 5

1

10

High-throughput

0.479

High

1342754

DMAP1
DNA methyltransferase 1-associated protein 1

1

2

High-throughput

0.479

High

1345386

MBIP1
MAP3K12-binding inhibitory protein 1

1

1

High-throughput

0.479

High

1348286

DDX56
Probable ATP-dependent RNA helicase DDX56

1

16

High-throughput

0.479

High

1350247

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

18

High-throughput

0.479

High

1350413

RCOR3
REST corepressor 3

1

17

High-throughput

0.479

High

1354420

ZMYM2
Zinc finger MYM-type protein 2

1

17

High-throughput

0.479

High

1355451

TRPS1
Zinc finger transcription factor Trps1

1

20

High-throughput

0.479

High

1356300

ING1
Inhibitor of growth protein 1

1

20

High-throughput

0.479

High

1356396

GMEB2
Glucocorticoid modulatory element-binding protein 2

1

11

High-throughput

0.479

High

1356504

RCOR1
REST corepressor 1

1

18

High-throughput

0.479

High

1356668

ZHX1
Zinc fingers and homeoboxes protein 1

1

20

High-throughput

0.479

High

1357297

KMT2B
Histone-lysine N-methyltransferase 2B

1

20

High-throughput

0.479

High

1357888

SMC3
Structural maintenance of chromosomes protein 3

1

6

High-throughput

0.479

High

1377629

NOP16
Nucleolar protein 16

1

6

High-throughput

0.479

High

1377807

TRRAP
Transformation/transcription domain-associated protein

1

4

High-throughput

0.479

High

1377909

ZHX2
Zinc fingers and homeoboxes protein 2

1

19

High-throughput

0.479

High

47332

A0A6Q8PF08
Peripheral myelin protein 22

1

3

High-throughput

0.470

High

574490

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.458

High

281479

RL1D1
Ribosomal L1 domain-containing protein 1

1

8

High-throughput

0.457

High

1314120

GNL3
Guanine nucleotide-binding protein-like 3

1

5

High-throughput

0.457

High

1317874

RM37
Large ribosomal subunit protein mL37

1

1

High-throughput

0.457

High

649853

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.445

High

296835

NOL4
Nucleolar protein 4

1

4

High-throughput

0.437

High

948540

RT06
Small ribosomal subunit protein bS6m

1

1

High-throughput

0.437

High

981503

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

5

High-throughput

0.437

High

1040857

PWP1
Periodic tryptophan protein 1 homolog

1

20

High-throughput

0.437

High

1150390

RL7L
Ribosomal protein uL30-like

1

3

High-throughput

0.437

High

1292696

DDX27
Probable ATP-dependent RNA helicase DDX27

1

12

High-throughput

0.437

High

1306856

EBP2
Probable rRNA-processing protein EBP2

1

3

High-throughput

0.437

High

1310069

CG050
Uncharacterized protein C7orf50

1

5

High-throughput

0.437

High

1310620

LLPH
Protein LLP homolog

1

1

High-throughput

0.437

High

1333569

DDX31
ATP-dependent DNA helicase DDX31

1

12

High-throughput

0.437

High

1336662

RM47
Large ribosomal subunit protein uL29m

1

1

High-throughput

0.437

High

1346789

DDX18
ATP-dependent RNA helicase DDX18

1

19

High-throughput

0.437

High

1357598

RL26L
Ribosomal protein uL24-like

1

11

High-throughput

0.437

High

1377353

RT28
Small ribosomal subunit protein bS1m

1

2

High-throughput

0.437

High

1377369

RT17
Small ribosomal subunit protein uS17m

1

1

High-throughput

0.437

High

1377663

RT18C
Small ribosomal subunit protein bS18m

1

8

High-throughput

0.437

High

1241860

B3GL2
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.279

Low

947342

RT10
Small ribosomal subunit protein uS10m

1

0

High-throughput

0.261

Low

1033259

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.261

Low

1377128

RT33
Small ribosomal subunit protein mS33

1

0

High-throughput

0.261

Low

928720

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.249

Low

1377620

RRP15
RRP15-like protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024