Protein: RFXK
DNA-binding protein RFXANK (Ankyrin repeat family A protein 1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein)

Gene: RFXK, RFXANK
Organism: Homo sapiens
Interactions: 150
UniProt ID: O14593

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

149816

RAF1
RAF proto-oncogene serine/threonine-protein kinase

3

14

Small-scale

0.847

High

149835

RFX5
DNA-binding protein RFX5

8

3

Small-scale

0.753

High

124318

RFXAP
Regulatory factor X-associated protein

5

1

Small-scale

0.729

High

149805

KS6A4
Ribosomal protein S6 kinase alpha-4

1

3

High-throughput

0.691

High

149807

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.691

High

149813

OXSR1
Serine/threonine-protein kinase OSR1

1

9

High-throughput

0.691

High

149820

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

15

High-throughput

0.691

High

149821

CD11B
Cyclin-dependent kinase 11B

1

4

High-throughput

0.691

High

149833

MK08
Mitogen-activated protein kinase 8

1

7

High-throughput

0.691

High

149849

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

19

High-throughput

0.691

High

149874

FIGL1
Fidgetin-like protein 1

1

17

High-throughput

0.691

High

149893

SSH3
Protein phosphatase Slingshot homolog 3

1

9

High-throughput

0.691

High

149896

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

16

High-throughput

0.691

High

149905

TONSL
Tonsoku-like protein

1

17

High-throughput

0.691

High

149907

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

17

High-throughput

0.691

High

149831

CASP2
Caspase-2

1

0

Small-scale

0.676

High

149866

RFX7
DNA-binding protein RFX7

3

11

Small-scale

0.670

High

149933

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.669

High

149853

BPTF
Nucleosome-remodeling factor subunit BPTF

2

20

High-throughput

0.628

High

149899

N42L2
NEDD4-binding protein 2-like 2

2

3

High-throughput

0.628

High

149826

C2TA
MHC class II transactivator

2

4

Small-scale

0.624

High

149888

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

17

High-throughput

0.618

High

149895

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

14

High-throughput

0.618

High

149796

RFXK
DNA-binding protein RFXANK

1

18

Small-scale

0.618

High

149799

AURKA
Aurora kinase A

1

4

High-throughput

0.618

High

149844

H4
Histone H4

1

4

High-throughput

0.618

High

149843

HDAC4
Histone deacetylase 4

2

20

Small-scale

0.613

High

149809

HAUS5
HAUS augmin-like complex subunit 5

2

0

High-throughput

0.602

High

149883

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.578

High

149935

HDAC9
Histone deacetylase 9

1

20

Small-scale

0.561

High

149938

HDAC5
Histone deacetylase 5

1

20

Small-scale

0.561

High

149797

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

20

High-throughput

0.536

High

149798

APAF
Apoptotic protease-activating factor 1

1

7

High-throughput

0.536

High

149800

ARHGA
Rho guanine nucleotide exchange factor 10

1

18

High-throughput

0.536

High

149801

ARHGB
Rho guanine nucleotide exchange factor 11

1

15

Small-scale

0.536

High

149803

PER1
Period circadian protein homolog 1

1

2

High-throughput

0.536

High

149804

SNX3
Sorting nexin-3

1

3

High-throughput

0.536

High

149806

RAD17
Cell cycle checkpoint protein RAD17

1

5

High-throughput

0.536

High

149808

PRP6
Pre-mRNA-processing factor 6

1

3

High-throughput

0.536

High

149811

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

6

High-throughput

0.536

High

149812

SMC2
Structural maintenance of chromosomes protein 2

1

11

High-throughput

0.536

High

149815

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

5

Small-scale

0.536

High

149819

UBL4A
Ubiquitin-like protein 4A

1

6

Small-scale

0.536

High

149822

DPOD1
DNA polymerase delta catalytic subunit

1

3

High-throughput

0.536

High

149823

SMCA1
Probable global transcription activator SNF2L1

1

7

High-throughput

0.536

High

149824

KPYR
Pyruvate kinase PKLR

1

2

High-throughput

0.536

High

149829

RFC3
Replication factor C subunit 3

1

3

High-throughput

0.536

High

149834

BAG6
Large proline-rich protein BAG6

1

4

Small-scale

0.536

High

149838

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

3

High-throughput

0.536

High

149846

GTF2I
General transcription factor II-I

1

2

High-throughput

0.536

High

149847

FOXK1
Forkhead box protein K1

1

7

High-throughput

0.536

High

149848

VIGLN
Vigilin

1

9

High-throughput

0.536

High

149850

FOXK2
Forkhead box protein K2

1

7

High-throughput

0.536

High

149852

DPOE1
DNA polymerase epsilon catalytic subunit A

1

3

High-throughput

0.536

High

149856

TIF1B
Transcription intermediary factor 1-beta

1

11

Small-scale

0.536

High

149857

RIN1
Ras and Rab interactor 1

1

2

High-throughput

0.536

High

149860

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

13

High-throughput

0.536

High

149862

CND1
Condensin complex subunit 1

1

3

High-throughput

0.536

High

149864

NAB2
NGFI-A-binding protein 2

1

1

High-throughput

0.536

High

149867

QRIC1
Transcriptional regulator QRICH1

1

8

High-throughput

0.536

High

149868

RGL3
Ral guanine nucleotide dissociation stimulator-like 3

1

3

High-throughput

0.536

High

149873

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

1

High-throughput

0.536

High

149876

SAMD1
Sterile alpha motif domain-containing protein 1

1

9

High-throughput

0.536

High

149880

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

10

Small-scale

0.536

High

149882

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

12

High-throughput

0.536

High

149885

I2BP1
Interferon regulatory factor 2-binding protein 1

1

1

High-throughput

0.536

High

149886

FOXP4
Forkhead box protein P4

1

7

High-throughput

0.536

High

149887

CEP97
Centrosomal protein of 97 kDa

1

4

High-throughput

0.536

High

149889

SMC5
Structural maintenance of chromosomes protein 5

1

8

High-throughput

0.536

High

149894

CTF18
Chromosome transmission fidelity protein 18 homolog

1

9

High-throughput

0.536

High

149900

RAD50
DNA repair protein RAD50

1

7

High-throughput

0.536

High

149901

ARHG1
Rho guanine nucleotide exchange factor 1

1

11

High-throughput

0.536

High

149902

NACC2
Nucleus accumbens-associated protein 2

1

11

High-throughput

0.536

High

149909

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

1

High-throughput

0.536

High

149910

PHB2
Prohibitin-2

1

2

Small-scale

0.536

High

149912

NPAS1
Neuronal PAS domain-containing protein 1

1

4

High-throughput

0.536

High

149913

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

2

High-throughput

0.536

High

149916

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.536

High

149918

NUF2
Kinetochore protein Nuf2

1

6

High-throughput

0.536

High

149922

FA83D
Protein FAM83D

1

1

High-throughput

0.536

High

149923

ESRP2
Epithelial splicing regulatory protein 2

1

7

High-throughput

0.536

High

149924

TF7L2
Transcription factor 7-like 2

1

8

High-throughput

0.536

High

149925

SMC4
Structural maintenance of chromosomes protein 4

1

12

High-throughput

0.536

High

149927

RNF12
E3 ubiquitin-protein ligase RLIM

1

3

High-throughput

0.536

High

149929

NALP2
NACHT, LRR and PYD domains-containing protein 2

1

4

High-throughput

0.536

High

149930

RTEL1
Regulator of telomere elongation helicase 1

1

2

High-throughput

0.536

High

149931

POGK
Pogo transposable element with KRAB domain

1

12

High-throughput

0.536

High

149936

TTF2
Transcription termination factor 2

1

7

High-throughput

0.536

High

149937

TBD2B
TBC1 domain family member 2B

1

5

High-throughput

0.536

High

149841

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

5

High-throughput

0.515

High

149859

DCTN1
Dynactin subunit 1

1

6

High-throughput

0.515

High

149802

FANCA
Fanconi anemia group A protein

1

0

High-throughput

0.513

High

149814

DYR
Dihydrofolate reductase

1

0

High-throughput

0.513

High

149836

PRI1
DNA primase small subunit

1

0

High-throughput

0.513

High

149837

PRI2
DNA primase large subunit

1

0

High-throughput

0.513

High

149839

KNTC1
Kinetochore-associated protein 1

1

0

High-throughput

0.513

High

149840

BRCA2
Breast cancer type 2 susceptibility protein

1

0

High-throughput

0.513

High

149842

PMS1
PMS1 protein homolog 1

1

0

High-throughput

0.513

High

149875

BRAT1
BRCA1-associated ATM activator 1

1

0

High-throughput

0.513

High

149878

SETX
Probable helicase senataxin

1

0

High-throughput

0.513

High

149890

BANP
Protein BANP

1

0

High-throughput

0.513

High

149891

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.513

High

149892

KNL1
Kinetochore scaffold 1

1

0

High-throughput

0.513

High

149898

SYMPK
Symplekin

1

0

High-throughput

0.513

High

149906

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.513

High

149915

DCC1
Sister chromatid cohesion protein DCC1

1

0

High-throughput

0.513

High

149917

PAPOG
Poly(A) polymerase gamma

1

0

High-throughput

0.513

High

149928

UCKL1
Uridine-cytidine kinase-like 1

1

0

High-throughput

0.513

High

149932

NCDN
Neurochondrin

1

0

High-throughput

0.513

High

149939

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.513

High

149940

MTO1
Protein MTO1 homolog, mitochondrial

1

0

High-throughput

0.513

High

149941

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

149904

PTCD3
Small ribosomal subunit protein mS39

1

0

High-throughput

0.493

High

149810

MTCL2
Microtubule cross-linking factor 2

1

9

Small-scale

0.489

High

149817

TSP1
Thrombospondin-1

1

12

High-throughput

0.489

High

149851

LMNB2
Lamin-B2

1

6

Small-scale

0.489

High

149863

MARE2
Microtubule-associated protein RP/EB family member 2

1

4

High-throughput

0.489

High

149869

ODAD2
Outer dynein arm-docking complex subunit 2

1

12

High-throughput

0.489

High

149870

PR14L
Protein PRR14L

1

3

High-throughput

0.489

High

149877

STXB4
Syntaxin-binding protein 4

1

10

High-throughput

0.489

High

149881

PKHH3
Pleckstrin homology domain-containing family H member 3

1

1

High-throughput

0.489

High

149911

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

6

High-throughput

0.489

High

149926

ABCF3
ATP-binding cassette sub-family F member 3

1

3

High-throughput

0.489

High

149934

HOOK1
Protein Hook homolog 1

1

6

High-throughput

0.489

High

149830

HNF4A
Hepatocyte nuclear factor 4-alpha

1

14

High-throughput

0.479

High

149832

HD
Huntingtin

1

3

Small-scale

0.479

High

149845

H31
Histone H3.1

1

12

High-throughput

0.479

High

149861

NFIX
Nuclear factor 1 X-type

1

9

High-throughput

0.479

High

149865

TBR1
T-box brain protein 1

1

1

High-throughput

0.479

High

149871

BLT3A
Bridge-like lipid transfer protein family member 3A

1

1

Small-scale

0.479

High

149897

HDAC2
Histone deacetylase 2

1

12

Small-scale

0.479

High

149919

ARP6
Actin-related protein 6

1

6

High-throughput

0.479

High

149818

CO1A2
Collagen alpha-2(I) chain

1

1

Small-scale

0.470

High

149827

BASI
Basigin

1

5

High-throughput

0.470

High

149828

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

2

High-throughput

0.470

High

149858

NFYC
Nuclear transcription factor Y subunit gamma

1

0

High-throughput

0.458

High

48774

BLT3B
Bridge-like lipid transfer protein family member 3B

1

1

Small-scale

0.445

High

149920

CCDC8
Coiled-coil domain-containing protein 8

1

2

Small-scale

0.445

High

149854

NPRL3
GATOR1 complex protein NPRL3

1

0

High-throughput

0.279

Low

149855

COASY
Bifunctional coenzyme A synthase

1

0

High-throughput

0.279

Low

149872

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.279

Low

149879

BTLA
B- and T-lymphocyte attenuator

1

0

High-throughput

0.279

Low

149884

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.279

Low

149903

KBP
KIF-binding protein

1

0

High-throughput

0.279

Low

149908

CE034
Uncharacterized protein C5orf34

1

0

High-throughput

0.279

Low

149921

KLK15
Kallikrein-15

1

0

High-throughput

0.279

Low

149914

RCAF1
GEL complex subunit OPTI

1

0

High-throughput

0.269

Low

149942

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.249

Low

149825

SC6A4
Sodium-dependent serotonin transporter

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024