Protein: HPRT
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8) (Bypass of repression by adenine protein 6)

Gene: HPRT, HPT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 13
UniProt ID: Q04178

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0004422 - hypoxanthine phosphoribosyltransferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006166 - purine ribonucleoside salvage

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1045142

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

3

3

Small-scale

0.828

High

866190

XPT1
Xanthine phosphoribosyltransferase 1

1

3

High-throughput

0.590

High

708093

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

735147

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

525056

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.458

High

844439

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.458

High

1045143

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

819713

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

924723

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

795199

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

528867

RLA3
Large ribosomal subunit protein P1B

1

0

High-throughput

0.238

Low

1045144

VPS5
Vacuolar protein sorting-associated protein 5

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025