Protein: IL1B
Interleukin-1 beta (IL-1 beta)

Gene: IL1B
Organism: Mus musculus
Interactions: 16
UniProt ID: P10749

Gene Ontology (top 5):
GO:0001660 - fever generation
GO:0005125 - cytokine activity
GO:0005149 - interleukin-1 receptor binding
GO:0005178 - integrin binding
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

532185

CASP1
Caspase-1

2

7

Small-scale

0.737

High

313441

CASP8
Caspase-8

2

7

Small-scale

0.659

High

532182

ILRL1
Interleukin-1 receptor-like 1

1

11

Small-scale

0.618

High

432054

JUN
Transcription factor Jun

2

3

Small-scale

0.584

High

532188

TF65
Transcription factor p65

2

7

Small-scale

0.584

High

532181

IL1R1
Interleukin-1 receptor type 1

1

12

Small-scale

0.575

High

532187

CASP3
Caspase-3

1

7

Small-scale

0.575

High

532183

SPI1
Transcription factor PU.1

1

3

Small-scale

0.479

High

532184

CEBPB
CCAAT/enhancer-binding protein beta

1

4

Small-scale

0.479

High

532186

IRF5
Interferon regulatory factor 5

1

2

Small-scale

0.479

High

532190

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

4

Small-scale

0.479

High

532193

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

1

Small-scale

0.479

High

532189

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

0

Small-scale

0.458

High

532191

NRIP1
Nuclear receptor-interacting protein 1

1

0

Small-scale

0.458

High

532194

NCOR2
Nuclear receptor corepressor 2

1

3

Small-scale

0.437

High

532192

SENP3
Sentrin-specific protease 3

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025