Protein: PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta) (Serine/threonine protein kinase PIK3CB) (EC 2.7.11.1)

Gene: PK3CB, Pik3cb
Organism: Mus musculus
Interactions: 19
UniProt ID: Q8BTI9

Gene Ontology (top 5):
GO:0001935 - endothelial cell proliferation
GO:0001952 - regulation of cell-matrix adhesion
GO:0002931 - response to ischemia
GO:0003376 - sphingosine-1-phosphate receptor signaling pathway
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

686981

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

3

20

Small-scale

0.821

High

1225134

CRK
Adapter molecule crk

1

18

High-throughput

0.691

High

953809

CDC42
Cell division control protein 42 homolog

1

20

Small-scale

0.665

High

988901

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.665

High

1222729

RASH
GTPase HRas

1

20

Small-scale

0.618

High

1225324

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

20

High-throughput

0.590

High

609544

PCNA
Proliferating cell nuclear antigen

1

1

Small-scale

0.578

High

1015959

RHOG
Rho-related GTP-binding protein RhoG

1

20

Small-scale

0.553

High

1208536

DIRA2
GTP-binding protein Di-Ras2

1

13

Small-scale

0.553

High

1297338

DIRA1
GTP-binding protein Di-Ras1

1

12

Small-scale

0.553

High

1239604

RAD17
Cell cycle checkpoint protein RAD17

1

2

Small-scale

0.515

High

1297342

NBN
Nibrin

1

5

Small-scale

0.515

High

1297343

GAB2
GRB2-associated-binding protein 2

1

7

Small-scale

0.500

High

644376

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

1

High-throughput

0.479

High

1297340

FAK2
Protein-tyrosine kinase 2-beta

1

18

Small-scale

0.479

High

945506

ERP29
Endoplasmic reticulum resident protein 29

1

1

High-throughput

0.457

High

1297341

YLPM1
YLP motif-containing protein 1

1

2

High-throughput

0.457

High

651555

CBL
E3 ubiquitin-protein ligase CBL

1

8

High-throughput

0.445

High

1297339

EXOS5
Exosome complex component RRP46

1

0

High-throughput

0.438

High


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Last updated: 11Aug2025